Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T cell-mediated autoimmune colitis
Chae W, Hao L, Henegariu O, Yilmaz S, Bothwell A. Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T cell-mediated autoimmune colitis. The Journal Of Immunology 2017, 198: 156.8-156.8. DOI: 10.4049/jimmunol.198.supp.156.8.Peer-Reviewed Original ResearchDKK-1 expressionDickkopf-1T cellsImmunological toleranceT cell-mediated toleranceEffector CD4 T cellsT cell-mediated colitisRegulatory T cellsCD4 T cellsT cell receptor stimulationCell receptor stimulationActivated TregsAutoimmune colitisTreg markersColitis modelReceptor stimulationTregsCanonical Wnt pathwayDe novo protein synthesisCell proliferationColitisWnt pathwayNovo protein synthesisMAPK pathwayWnt ligands