2022
What’s new in the management of neonatal early-onset sepsis?
Fleiss N, Schwabenbauer K, Randis TM, Polin RA. What’s new in the management of neonatal early-onset sepsis? Archives Of Disease In Childhood - Fetal And Neonatal Edition 2022, 108: 10-14. PMID: 35618407, DOI: 10.1136/archdischild-2021-323532.Peer-Reviewed Original ResearchInfection prevention for extremely low birth weight infants in the NICU
Fleiss N, Tarun S, Polin RA. Infection prevention for extremely low birth weight infants in the NICU. Seminars In Fetal And Neonatal Medicine 2022, 27: 101345. PMID: 35550785, PMCID: PMC9006400, DOI: 10.1016/j.siny.2022.101345.Peer-Reviewed Original ResearchConceptsInfection preventionLow birth weight infantsEarly antibiotic exposureBirth weight infantsHuman milk feedingPreterm newborn infantsSARS-CoV-2 global pandemicUse of probioticsAntifungal prophylaxisEnteral feedingWeight infantsPreterm infantsProlonged hospitalizationEvidence-based practiceMilk feedingNewborn infantsAntibiotic exposureInvasive interventionsSystemic infectionImmune defenseInfantsInfectionPreventionSuch interventionsNICU
2021
Can we back off using antibiotics in the NICU?
Fleiss N, Hooven TA, Polin RA. Can we back off using antibiotics in the NICU? Seminars In Fetal And Neonatal Medicine 2021, 26: 101217. PMID: 33678550, DOI: 10.1016/j.siny.2021.101217.Peer-Reviewed Original ResearchConceptsMulti-drug resistant organismsLong-term adverse effectsCulture-positive sepsisAntibiotic prescribing practicesDelaying antibioticsNeonatal sepsisPositive sepsisPrescribing practicesAntibiotic utilizationNeonatal ICUAntibiotic stewardshipAntibiotic useAntibiotic overuseResistant organismsAdverse effectsAntibioticsSepsisNICUInfantsLaboratory testingICUNeonatesSpecified intervalsNeonatologistsClinical and vital sign changes associated with late-onset sepsis in very low birth weight infants at 3 NICUs.
Sullivan BA, Nagraj VP, Berry KL, Fleiss N, Rambhia A, Kumar R, Wallman-Stokes A, Vesoulis ZA, Sahni R, Ratcliffe S, Lake DE, Moorman JR, Fairchild KD. Clinical and vital sign changes associated with late-onset sepsis in very low birth weight infants at 3 NICUs. Journal Of Neonatal-Perinatal Medicine 2021, 14: 553-561. PMID: 33523025, PMCID: PMC8316489, DOI: 10.3233/npm-200578.Peer-Reviewed Original ResearchConceptsLate-onset sepsisLow birth weight infantsBirth weight infantsClinical signsWeight infantsHeart rateBaseline risk factorsVital sign changesNon-infectious conditionsAbnormal CBCFirst sepsisAbdominal distensionVLBW infantsCentral cathetersMechanical ventilationPremature infantsPostnatal ageBaseline variablesClinician documentationRisk factorsClinical changesSepsisInfantsVital signsLogistic regression