2022
The first 20 months of the COVID-19 pandemic: Mortality, intubation and ICU rates among 104,590 patients hospitalized at 21 United States health systems
Fiore M, Smith S, Adsit R, Bolt D, Conner K, Bernstein S, Eng O, Lazuk D, Gonzalez A, Jorenby D, D’Angelo H, Kirsch J, Williams B, Nolan M, Hayes-Birchler T, Kent S, Kim H, Piasecki T, Slutske W, Lubanski S, Yu M, Suk Y, Cai Y, Kashyap N, Mathew J, McMahan G, Rolland B, Tindle H, Warren G, An L, Boyd A, Brunzell D, Carrillo V, Chen L, Davis J, Dilip D, Ellerbeck E, Iturrate E, Jose T, Khanna N, King A, Klass E, Newman M, Shoenbill K, Tong E, Tsoh J, Wilson K, Theobald W, Baker T. The first 20 months of the COVID-19 pandemic: Mortality, intubation and ICU rates among 104,590 patients hospitalized at 21 United States health systems. PLOS ONE 2022, 17: e0274571. PMID: 36170336, PMCID: PMC9518859, DOI: 10.1371/journal.pone.0274571.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsICU admission rateUnited States health systemState health systemAdmission ratesPositive COVID-19 PCR testCOVID-19 PCR testHospitalized COVID-19 patientsHealth systemHealth system contactElectronic health record dataICD-10 diagnosisAge 18 yearsCOVID-19 hospitalizationRisk-standardized mortalityHealth record dataHigh mortality rateCOVID-19 pandemicICU admissionHospitalized participantsEndotracheal intubationIntubation rateMean agePatient groupPatient outcomesSmoking Status, Nicotine Medication, Vaccination, and COVID-19 Hospital Outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) Study
Piasecki T, Smith S, Baker T, Slutske W, Adsit R, Bolt D, Conner K, Bernstein S, Eng O, Lazuk D, Gonzalez A, Jorenby D, D’Angelo H, Kirsch J, Williams B, Nolan M, Hayes-Birchler T, Kent S, Kim H, Lubanski S, Yu M, Suk Y, Cai Y, Kashyap N, Mathew J, McMahan G, Rolland B, Tindle H, Warren G, An L, Boyd A, Brunzell D, Carrillo V, Chen L, Davis J, Deshmukh V, Dilip D, Ellerbeck E, Goldstein A, Iturrate E, Jose T, Khanna N, King A, Klass E, Mermelstein R, Tong E, Tsoh J, Wilson K, Theobald W, Fiore M. Smoking Status, Nicotine Medication, Vaccination, and COVID-19 Hospital Outcomes: Findings from the COVID EHR Cohort at the University of Wisconsin (CEC-UW) Study. Nicotine & Tobacco Research 2022, 25: 1184-1193. PMID: 36069915, PMCID: PMC9494410, DOI: 10.1093/ntr/ntac201.Peer-Reviewed Original ResearchConceptsNicotine replacement therapySARS-CoV-2 vaccinationCOVID-19 patientsCurrent smokersFormer smokersSmoking statusCOVID-19 outcomesICU admissionNRT prescriptionHospital outcomesVaccination statusReplacement therapySevere COVID-19 disease outcomesCOVID-19 clinical outcomesCOVID-19 disease outcomesBetter hospital outcomesOdds of deathBody mass indexElectronic health record dataLarge cohort studyCOVID-19 hospitalizationHealth record dataPotential beneficial effectsU.S. health systemEHR cohortRelations of Current and Past Cancer with Severe Outcomes among 104,590 Hospitalized COVID-19 Patients: The COVID EHR Cohort at the University of Wisconsin
Nolan M, Piasecki T, Smith S, Baker T, Fiore M, Adsit R, Bolt D, Conner K, Bernstein S, Eng O, Lazuk D, Gonzalez A, Hayes-Birchler T, Jorenby D, D'Angelo H, Kirsch J, Williams B, Kent S, Kim H, Lubanski S, Yu M, Suk Y, Cai Y, Kashyap N, Mathew J, McMahan G, Rolland B, Tindle H, Warren G, Abu-el-rub N, An L, Boyd A, Brunzell D, Carrillo V, Chen L, Davis J, Deshmukh V, Dilip D, Goldstein A, Ha P, Iturrate E, Jose T, Khanna N, King A, Klass E, Lui M, Mermelstein R, Poon C, Tong E, Wilson K, Theobald W, Slutske W. Relations of Current and Past Cancer with Severe Outcomes among 104,590 Hospitalized COVID-19 Patients: The COVID EHR Cohort at the University of Wisconsin. Cancer Epidemiology Biomarkers & Prevention 2022, 32: 12-21. PMID: 35965473, PMCID: PMC9827105, DOI: 10.1158/1055-9965.epi-22-0500.Peer-Reviewed Original ResearchConceptsSevere COVID-19 outcomesCOVID-19 outcomesCurrent cancerCOVID-19 vaccinationPast cancerICU admissionSevere outcomesCancer typesCancer diagnosisHistory of cancerElectronic health record dataCOVID-19 patientsHealth record dataUnited States health systemCOVID-19State health systemEHR cohortHospital mortalityVaccination statusYounger patientsPatient characteristicsCancer characteristicsMost cancer typesOdds ratioHigh risk
2021
The potential impact of triage protocols on racial disparities in clinical outcomes among COVID-positive patients in a large academic healthcare system
Roy S, Showstark M, Tolchin B, Kashyap N, Bonito J, Salazar MC, Herbst JL, Nash KA, Tiako M, Jubanyik K, Kim N, Galusha D, Wang KH, Oladele C. The potential impact of triage protocols on racial disparities in clinical outcomes among COVID-positive patients in a large academic healthcare system. PLOS ONE 2021, 16: e0256763. PMID: 34529684, PMCID: PMC8445412, DOI: 10.1371/journal.pone.0256763.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlack or African AmericanConnecticutCOVID-19Delivery of Health CareFemaleHealthcare DisparitiesHispanic or LatinoHospital MortalityHospitals, UniversityHumansMaleMiddle AgedOrgan Dysfunction ScoresPandemicsRetrospective StudiesSARS-CoV-2TriageWhite PeopleYoung AdultConceptsCOVID-positive patientsHigher SOFA scoreSOFA scoreClinical outcomesBlack patientsHospital mortalityICU admissionTriage protocolYale New Haven Health SystemSequential Organ Failure Assessment scoreHealthcare systemLarge academic healthcare systemOrgan Failure Assessment scoreRacial disparitiesSimilar clinical outcomesWorse clinical outcomesAcademic healthcare systemChi-square testRace/ethnicityPredictors of interestRetrospective cohortWhite patientsInsurance statusCOVID patientsTriage tool