Thymidylate synthase as a translational regulator of cellular gene expression
Liu J, Schmitz JC, Lin X, Tai N, Yan W, Farrell M, Bailly M, Chen T, Chu E. Thymidylate synthase as a translational regulator of cellular gene expression. Biochimica Et Biophysica Acta 2002, 1587: 174-182. PMID: 12084459, DOI: 10.1016/s0925-4439(02)00080-7.Peer-Reviewed Original ResearchConceptsTranslational regulatorCell cycleRNA binding proteinCellular gene expressionProcess of apoptosisTumor suppressor geneFolate-dependent enzymesTranslational repressionCellular mRNAsCognate mRNATranscription factorsMRNA interactionsMyc familyVivo model systemsGene expressionTS proteinCellular resistanceSuppressor geneBinding proteinMolecular elementsP53 tumor suppressor geneFunctional consequencesAbility of TSAutoregulatory controlProtein