2007
Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women
Stachenfeld NS, Taylor HS. Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women. Clinical Endocrinology 2007, 66: 410-418. PMID: 17302877, DOI: 10.1111/j.1365-2265.2007.02748.x.Peer-Reviewed Original ResearchConceptsExtracellular fluid volumeTranscapillary albumin escape rateGonadotropin-releasing hormone antagonistPmol/Plasma renin activitySerum aldosterone concentrationHealthy young womenAlbumin escape rateRenin activityAldosterone concentrationGnRH antagonistHealthy womenProgesterone administrationExogenous oestradiolIntravascular volumeHormone antagonistProgesterone increaseDay 2Day 5Hormone treatmentOestradiolDay 13Extravascular componentOncotic pressureYoung women
2001
Estrogen and progesterone effects on transcapillary fluid dynamics
Stachenfeld N, Keefe D, Palter S. Estrogen and progesterone effects on transcapillary fluid dynamics. AJP Regulatory Integrative And Comparative Physiology 2001, 281: r1319-r1329. PMID: 11557642, DOI: 10.1152/ajpregu.2001.281.4.r1319.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial Natriuretic FactorBlood PressureBlood VolumeCapillariesCapillary PermeabilityCardiac OutputDrug Administration RoutesEstradiolEstrogensFemaleFertility Agents, FemaleForearmGonadotropin-Releasing HormoneHematocritHot FlashesHumansInfusions, IntravenousLeuprolideProgesteroneStroke VolumeVeinsConceptsCapillary filtration coefficientANP infusionGnRH analoguesPlasma volumeProgesterone effectsTranscapillary fluid dynamicsGonadotropin-releasing hormone analogueLittle systemic effectMin of infusionBaseline plasma volumeHormone administrationPV lossSystemic effectsReproductive functionInfusionAdministrationTreatmentEstrogenPeptide controlFiltration coefficientWeeksWomenANPDaysHematocrit
1997
Transcapillary escape rate of albumin in humans during exercise-induced hypervolemia
Haskell A, Nadel E, Stachenfeld N, Nagashima K, Mack G. Transcapillary escape rate of albumin in humans during exercise-induced hypervolemia. Journal Of Applied Physiology 1997, 83: 407-413. PMID: 9262434, DOI: 10.1152/jappl.1997.83.2.407.Peer-Reviewed Original ResearchConceptsCapillary filtration coefficientTranscapillary escape rateLeg musclesUpright cycle ergometer exerciseVascular spaceTranscapillary forcesInterstitial fluid hydrostatic pressureCycle ergometer exercisePlasma albumin concentrationPlasma colloid osmotic pressureExercise-induced hypervolemiaColloid osmotic pressureErgometer exerciseIntense exerciseTotal protein concentrationFluid hydrostatic pressureAlbumin concentrationTERalbMuscleFiltration coefficientExerciseActive tissuesAlbuminLegProtein concentration