2023
Guidelines on the use of sex and gender in cardiovascular research
Usselman C, Lindsey M, Robinson A, Habecker B, Taylor C, Merryman W, Kimmerly D, Bender J, Regensteiner J, Moreau K, Pilote L, Wenner M, O'Brien M, Yarovinsky T, Stachenfeld N, Charkoudian N, Denfeld Q, Moreira-Bouchard J, Pyle W, DeLeon-Pennell K. Guidelines on the use of sex and gender in cardiovascular research. AJP Heart And Circulatory Physiology 2023, 326: h238-h255. PMID: 37999647, PMCID: PMC11219057, DOI: 10.1152/ajpheart.00535.2023.Peer-Reviewed Original ResearchThe Biological Basis of Sex Differences in Athletic Performance: Consensus Statement for the American College of Sports Medicine
HUNTER S, ANGADI S, BHARGAVA A, HARPER J, HIRSCHBERG A, LEVINE B, MOREAU K, NOKOFF N, STACHENFELD N, BERMON S. The Biological Basis of Sex Differences in Athletic Performance: Consensus Statement for the American College of Sports Medicine. Medicine & Science In Sports & Exercise 2023, 55: 2328-2360. PMID: 37772882, DOI: 10.1249/mss.0000000000003300.Peer-Reviewed Original ResearchMeSH KeywordsAdultAthletic PerformanceFemaleGonadal Steroid HormonesHumansMaleSex CharacteristicsSports MedicineTestosteroneTestosterone CongenersUnited StatesConceptsSex steroid hormonesConsensus statementAthletic performanceEndogenous sex steroid hormonesSex differencesSteroid hormonesOnset of pubertyExercise trainingMuscle strengthAcute boutFundamental sex differencesSex hormonesAmerican CollegeParticular testosteroneAdult menSports medicineTraining statusHigh-impact studiesHormoneSimilar ageNonphysiological factorsPrimary determinantMalesBiological basisWomen
2022
Are there sex differences in risk for exertional heat stroke? A translational approach
Giersch GEW, Garcia CK, Stachenfeld N, Charkoudian N. Are there sex differences in risk for exertional heat stroke? A translational approach. Quarterly Journal Of Experimental Physiology And Cognate Medical Sciences 2022, 107: 1136-1143. PMID: 35598159, DOI: 10.1113/ep090402.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBody Temperature RegulationFemaleGonadal Steroid HormonesHeat Stress DisordersHeat StrokeHumansMaleSex CharacteristicsConceptsExertional heat strokeHeat strokeRisk factorsTranslational approachCentral nervous system dysfunctionNervous system dysfunctionFemale sex hormonesSex differencesHuman researchOrgan damageFatal conditionSystem dysfunctionSex hormonesPhysical activityStrokeTranslational modelOccupational workersRiskMilitary personnelAnimalsTreatmentHuman modelReviewFuture investigationsPhysiological differencesPrecision medicine requires understanding how both sex and gender influence health
Stachenfeld NS, Mazure CM. Precision medicine requires understanding how both sex and gender influence health. Cell 2022, 185: 1619-1622. PMID: 35561661, DOI: 10.1016/j.cell.2022.04.012.Peer-Reviewed Original Research
2014
Reproductive Hormone Influences on Thermoregulation in Women
Charkoudian N, Stachenfeld NS. Reproductive Hormone Influences on Thermoregulation in Women. 2014, 4: 793-804. PMID: 24715568, DOI: 10.1002/cphy.c130029.ChaptersConceptsReproductive hormonesHormone exposurePeripheral thermal informationReproductive hormone effectsMale reproductive hormonesBody temperatureThermoregulatory responsesProgesterone/progestinsPeripheral mechanismsAnterior hypothalamusPreoptic areaHormone influenceHormone effectsLow body temperatureBody heatingYoung womenThermoregulatory controlEnvironmental exposuresWomenHormoneMajor quantitative differencesProgestinsAndrogensEstrogenPhysiological thermoregulatory responses
2001
Selected Contribution: Sex differences in osmotic regulation of AVP and renal sodium handling
Stachenfeld N, Splenser A, Calzone W, Taylor M, Keefe D. Selected Contribution: Sex differences in osmotic regulation of AVP and renal sodium handling. Journal Of Applied Physiology 2001, 91: 1893-1901. PMID: 11568177, DOI: 10.1152/jappl.2001.91.4.1893.Peer-Reviewed Original ResearchConceptsSystolic blood pressureBlood pressureMenstrual phaseBasal plasma AVP concentrationGreater systolic blood pressurePressure-natriuresis curveRenal sodium handlingPlasma osmolalityPlasma AVP concentrationMin of restMidluteal menstrual phasesBasal plasma osmolalitySex differencesSodium handlingPulse pressureBody wtAVP concentrationAVP releaseNaCl infusionHormone responseMenWomenGreater sensitivityBody waterOsmolality
1991
Evaluation of 85% predicted maximal heart rate as an end point for diagnostic exercise testing
Coplan N, Gleim G, Stachenfeld N, Eskenazi M, Morales M, Nicholas J. Evaluation of 85% predicted maximal heart rate as an end point for diagnostic exercise testing. American Heart Journal 1991, 122: 1790-1791. PMID: 1957782, DOI: 10.1016/0002-8703(91)90307-4.Peer-Reviewed Original ResearchGender differences in the systolic blood pressure response to exercise
Gleim G, Stachenfeld N, Coplan N, Nicholas J. Gender differences in the systolic blood pressure response to exercise. American Heart Journal 1991, 121: 524-530. PMID: 1990758, DOI: 10.1016/0002-8703(91)90721-s.Peer-Reviewed Original ResearchMeSH KeywordsBlood PressureBody WeightEpinephrineExerciseFemaleHeart RateHumansMaleNorepinephrineOxygen ConsumptionReference ValuesSex CharacteristicsSystoleConceptsSystolic blood pressure responseBlood pressure responseSystolic blood pressureBody surface areaLean body massBlood pressurePressure responseBody weightHigher systolic blood pressureSympathetic nervous system responsesNormal cardiac responseUrinary norepinephrine excretionPeak heart rateNervous system responsesGender differencesNorepinephrine excretionBody massExercise modalitiesDynamic exerciseHeart rateCardiac responseInfluence of genderMenModalitiesResponse
1990
The influence of flexibility on the economy of walking and jogging
Gleim G, Stachenfeld N, Nicholas J. The influence of flexibility on the economy of walking and jogging. Journal Of Orthopaedic Research® 1990, 8: 814-823. PMID: 2213338, DOI: 10.1002/jor.1100080606.Peer-Reviewed Original Research