2007
Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women
Stachenfeld NS, Taylor HS. Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women. Clinical Endocrinology 2007, 66: 410-418. PMID: 17302877, DOI: 10.1111/j.1365-2265.2007.02748.x.Peer-Reviewed Original ResearchConceptsExtracellular fluid volumeTranscapillary albumin escape rateGonadotropin-releasing hormone antagonistPmol/Plasma renin activitySerum aldosterone concentrationHealthy young womenAlbumin escape rateRenin activityAldosterone concentrationGnRH antagonistHealthy womenProgesterone administrationExogenous oestradiolIntravascular volumeHormone antagonistProgesterone increaseDay 2Day 5Hormone treatmentOestradiolDay 13Extravascular componentOncotic pressureYoung women
2005
Progesterone increases plasma volume independent of estradiol
Stachenfeld NS, Taylor HS. Progesterone increases plasma volume independent of estradiol. Journal Of Applied Physiology 2005, 98: 1991-1997. PMID: 15718411, DOI: 10.1152/japplphysiol.00031.2005.Peer-Reviewed Original ResearchConceptsTranscapillary escape ratePlasma concentrationsPlasma volumeGnRH antagonistECF volumeAdequate plasma volumeAldosterone system stimulationPlasma renin activityGonadotropin-releasing hormoneExtracellular fluid volumeRenin activitySerum aldosteroneAng IIBlood pressureEstrogen administrationSystem stimulationDay 2Day 5Pg/Day 13Fluid regulationPV expansionFluid volumeIndependent effectsProgesterone
2003
Effects of estrogen and progesterone administration on extracellular fluid
Stachenfeld NS, Taylor HS. Effects of estrogen and progesterone administration on extracellular fluid. Journal Of Applied Physiology 2003, 96: 1011-1018. PMID: 14660504, DOI: 10.1152/japplphysiol.01032.2003.Peer-Reviewed Original ResearchMeSH KeywordsAdultEstrogensExtracellular FluidFemaleGonadotropin-Releasing HormoneHumansLuteal PhasePlasma VolumeProgesteroneConceptsGnRH antagonist administrationExtracellular fluid volumeGnRH antagonistEffects of estrogenAntagonist administrationPlasma volumeTranscapillary escape rateGonadotropin-releasing hormoneExtracellular fluidHealthy womenProgesterone administrationECFV expansionGanirelix acetateEndogenous estrogensStrong negative predictorDay 2Day 5Pg/AntagonistEstrogenDay 12Plasma compartmentCapillary endotheliumAdministrationProgesterone
1999
Effects of oral contraceptives on body fluid regulation
Stachenfeld N, Silva C, Keefe D, Kokoszka C, Nadel E. Effects of oral contraceptives on body fluid regulation. Journal Of Applied Physiology 1999, 87: 1016-1025. PMID: 10484572, DOI: 10.1152/jappl.1999.87.3.1016.Peer-Reviewed Original ResearchConceptsBody fluid regulationLuteal phaseHighest plasma estradiol concentrationFluid regulationOral contraceptive administrationBody fluid retentionPlasma estradiol concentrationsMidluteal menstrual phasesBody fluid balanceArginine vasopressin concentrationBasal plasma osmolalityExercise dehydrationOral contraceptivesContraceptive administrationBody water balanceFluid retentionFollicular phaseEstradiol concentrationsAVP releaseMenstrual phaseFluid balanceVasopressin concentrationCrossover designThirst stimulationPlasma osmolality
1997
Transcapillary escape rate of albumin in humans during exercise-induced hypervolemia
Haskell A, Nadel E, Stachenfeld N, Nagashima K, Mack G. Transcapillary escape rate of albumin in humans during exercise-induced hypervolemia. Journal Of Applied Physiology 1997, 83: 407-413. PMID: 9262434, DOI: 10.1152/jappl.1997.83.2.407.Peer-Reviewed Original ResearchConceptsCapillary filtration coefficientTranscapillary escape rateLeg musclesUpright cycle ergometer exerciseVascular spaceTranscapillary forcesInterstitial fluid hydrostatic pressureCycle ergometer exercisePlasma albumin concentrationPlasma colloid osmotic pressureExercise-induced hypervolemiaColloid osmotic pressureErgometer exerciseIntense exerciseTotal protein concentrationFluid hydrostatic pressureAlbumin concentrationTERalbMuscleFiltration coefficientExerciseActive tissuesAlbuminLegProtein concentration