2022
Polycystic ovary syndrome and black race are associated with increased blood pressure
Okifo N, Pal L, Mushi M, Stachenfeld N. Polycystic ovary syndrome and black race are associated with increased blood pressure. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r3724.Peer-Reviewed Original ResearchOlder reproductive age womenReproductive-age womenNon-obese groupPolycystic ovary syndromeMultivariable linear regression modelsBlood pressureAge womenObese groupBlack raceBP indicesOvary syndromeRacial breakdownDiagnosis of PCOSNon-obese womenCardiovascular disease riskMultivariable linear regressionType II diabetesLinear regression modelsGreater systolicTubal infertilityIndependent predictorsCommon endocrinopathyRegression modelsBP measurementsPCOS
2021
Androgen Effects on Baroreflex Sensitivity in Women with AE‐PCOS
Stone T, Chiles M, Leone C, Pal L, Stachenfeld N. Androgen Effects on Baroreflex Sensitivity in Women with AE‐PCOS. The FASEB Journal 2021, 35 DOI: 10.1096/fasebj.2021.35.s1.04149.Peer-Reviewed Original ResearchMuscle sympathetic nerve activityLower body negative pressureSympathetic baroreflex sensitivityPolycystic ovary syndromeBaroreflex sensitivityBR controlDiastolic BPHormone suppressionImpaired blood pressure regulationGonadotropin-releasing hormone antagonistOral glucose tolerance testDays of GnRHSympathetic nerve activityInsulin-resistant womenMean arterial pressureVascular resistance changesReproductive-age womenGlucose tolerance testBody negative pressureBlood pressure regulationSuppression of E2Bursts/100 heartbeatsCardiovascular comorbiditiesPCOS phenotypeResistant women
2020
Autonomic Dysfunction in Women with Androgen Excess PCOS
Stone T, Leone C, Ayers T, Stachenfeld N. Autonomic Dysfunction in Women with Androgen Excess PCOS. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.01846.Peer-Reviewed Original ResearchLower body negative pressurePolycystic ovary syndromeForearm vascular resistanceGnRH-antBlood pressureBaroreflex sensitivityEstrogen suppressionBRS slopeHormone suppressionAutonomic functionElevated blood pressureReproductive-age womenBody negative pressureTestosterone-induced changesAutonomic dysfunctionMild hypertensionVascular resistanceObese womenOvary syndromeGnRH antagonistAge womenBP regulationCardiovascular diseaseReproductive endocrinopathyBiochemical manifestations