2008
Sex Hormone Effects on Body Fluid Regulation
Stachenfeld NS. Sex Hormone Effects on Body Fluid Regulation. Exercise And Sport Sciences Reviews 2008, 36: 152-159. PMID: 18580296, PMCID: PMC2849969, DOI: 10.1097/jes.0b013e31817be928.Peer-Reviewed Original Research
2005
Progesterone increases plasma volume independent of estradiol
Stachenfeld NS, Taylor HS. Progesterone increases plasma volume independent of estradiol. Journal Of Applied Physiology 2005, 98: 1991-1997. PMID: 15718411, DOI: 10.1152/japplphysiol.00031.2005.Peer-Reviewed Original ResearchConceptsTranscapillary escape ratePlasma concentrationsPlasma volumeGnRH antagonistECF volumeAdequate plasma volumeAldosterone system stimulationPlasma renin activityGonadotropin-releasing hormoneExtracellular fluid volumeRenin activitySerum aldosteroneAng IIBlood pressureEstrogen administrationSystem stimulationDay 2Day 5Pg/Day 13Fluid regulationPV expansionFluid volumeIndependent effectsProgesterone
2003
Effects of estrogen and progesterone administration on extracellular fluid
Stachenfeld NS, Taylor HS. Effects of estrogen and progesterone administration on extracellular fluid. Journal Of Applied Physiology 2003, 96: 1011-1018. PMID: 14660504, DOI: 10.1152/japplphysiol.01032.2003.Peer-Reviewed Original ResearchConceptsGnRH antagonist administrationExtracellular fluid volumeGnRH antagonistEffects of estrogenAntagonist administrationPlasma volumeTranscapillary escape rateGonadotropin-releasing hormoneExtracellular fluidHealthy womenProgesterone administrationECFV expansionGanirelix acetateEndogenous estrogensStrong negative predictorDay 2Day 5Pg/AntagonistEstrogenDay 12Plasma compartmentCapillary endotheliumAdministrationProgesterone
2001
Estrogen and progesterone effects on transcapillary fluid dynamics
Stachenfeld N, Keefe D, Palter S. Estrogen and progesterone effects on transcapillary fluid dynamics. AJP Regulatory Integrative And Comparative Physiology 2001, 281: r1319-r1329. PMID: 11557642, DOI: 10.1152/ajpregu.2001.281.4.r1319.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial Natriuretic FactorBlood PressureBlood VolumeCapillariesCapillary PermeabilityCardiac OutputDrug Administration RoutesEstradiolEstrogensFemaleFertility Agents, FemaleForearmGonadotropin-Releasing HormoneHematocritHot FlashesHumansInfusions, IntravenousLeuprolideProgesteroneStroke VolumeVeinsConceptsCapillary filtration coefficientANP infusionGnRH analoguesPlasma volumeProgesterone effectsTranscapillary fluid dynamicsGonadotropin-releasing hormone analogueLittle systemic effectMin of infusionBaseline plasma volumeHormone administrationPV lossSystemic effectsReproductive functionInfusionAdministrationTreatmentEstrogenPeptide controlFiltration coefficientWeeksWomenANPDaysHematocrit
1997
Mechanism of attenuated thirst in aging: role of central volume receptors
Stachenfeld N, DiPietro L, Nadel E, Mack G. Mechanism of attenuated thirst in aging: role of central volume receptors. American Journal Of Physiology 1997, 272: r148-r157. PMID: 9039003, DOI: 10.1152/ajpregu.1997.272.1.r148.Peer-Reviewed Original ResearchConceptsCentral blood volume expansionBlood volume expansionYoung subjectsOlder subjectsPlasma volumePlasma atrial natriuretic peptide concentrationAtrial natriuretic peptide concentrationsThirst ratingsOlder peopleFractional sodium excretionPlasma renin activityArterial blood pressureNatriuretic peptide concentrationsCentral volume expansionMin of headWater perfusion suitAd libitum water intakeAldosterone concentrationRenin activitySodium excretionArterial baroreceptorsArterial pressureBlood pressureRenal responseVolume receptors
1996
Fluid balance and renal response following dehydrating exercise in well-trained men and women
Stachenfeld N, Gleim G, Zabetakis P, Nicholas J. Fluid balance and renal response following dehydrating exercise in well-trained men and women. European Journal Of Applied Physiology 1996, 72: 468-477. PMID: 8925818, DOI: 10.1007/bf00242277.Peer-Reviewed Original ResearchConceptsPlasma renin activityEnd of exerciseSodium handlingMin postexerciseEarly recoveryFluid balanceLow plasma renin activityRenal free water clearancePlasma volumeFractional sodium excretionPlasma osmolalityFree water clearanceOverall fluid balanceMin of recoveryFluid-regulating hormonesRenin activitySodium excretionSerum aldosteroneNorepinephrine concentrationsRenal responseWater clearanceRenal waterAnaerobic thresholdWater reabsorptionWomen