2023
Effects of androgen excess and body mass index on endothelial function in women with polycystic ovary syndrome
Berbrier D, Leone C, Adler T, Bender J, Taylor H, Stachenfeld N, Usselman C. Effects of androgen excess and body mass index on endothelial function in women with polycystic ovary syndrome. Journal Of Applied Physiology 2023, 134: 868-878. PMID: 36861670, DOI: 10.1152/japplphysiol.00583.2022.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeEndothelial dysfunctionEndothelial functionOvary syndromeAndrogen excessLean womenObese womenEstradiol supplementationLow flow-mediated constrictionOW/OB groupOverweight/obese womenMarked endothelial dysfunctionSevere endothelial dysfunctionFree testosterone levelsBody mass indexFlow-mediated dilation (FMD) testFree testosteroneMass indexReactive hyperemiaOB groupTestosterone levelsHealth differEndothelial pathophysiologyDysfunctionAndrogens
2017
Relationship between body mass index and endothelial dysfunction in women with and without polycystic ovary syndrome
Adler T, Usselman C, Anaeto L, Schapiro R, Steele F, Toffoloni N, Takamata A, Taylor H, Stachenfeld N. Relationship between body mass index and endothelial dysfunction in women with and without polycystic ovary syndrome. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.691.8.Peer-Reviewed Original ResearchPolycystic ovary syndromeEndothelial dysfunctionOvary syndromeFlow-mediated dilation responseSympathetic nervous system activationCardiovascular disease riskBody mass indexFlow-mediated dilation (FMD) testAmerican Heart AssociationMinutes of occlusionNervous system activationRotterdam criteriaFMD responseBrachial arteryEndothelial functionEndothelial healthHealthy womenHyperemic responseMass indexSuprasystolic pressureControl womenHeart AssociationInsulin resistanceClinical indicesReproductive age