2013
Mechanisms contributing to low orthostatic tolerance in women: the influence of oestradiol
Wenner MM, Haddadin A, Taylor HS, Stachenfeld NS. Mechanisms contributing to low orthostatic tolerance in women: the influence of oestradiol. The Journal Of Physiology 2013, 591: 2345-2355. PMID: 23401618, PMCID: PMC3650699, DOI: 10.1113/jphysiol.2012.247882.Peer-Reviewed Original ResearchConceptsLow orthostatic toleranceE2 administrationOrthostatic toleranceVascular resistanceBlood pressureStroke volumeHeart rateGonadotrophin-releasing hormone antagonistLevels of LBNPLower central volumeReproductive hormone productionAdministration of E2Peripheral vascular resistanceBeat blood pressureAutonomic cardiovascular regulationLower stroke volumeLower body negative pressure testHeart rate responseInfluence of oestradiolBaroreflex controlTolerant womenHormone antagonistCardiovascular regulationPeripheral vasoconstrictionAutonomic control
2010
Greater orthostatic tolerance in young black compared to white women
Hinds K, Stachenfeld N. Greater orthostatic tolerance in young black compared to white women. The FASEB Journal 2010, 24: 977.9-977.9. DOI: 10.1096/fasebj.24.1_supplement.977.9.Peer-Reviewed Original ResearchLower body negative pressureOrthostatic toleranceWhite womenCumulative stress indexHeart rateLevels of LBNPR intervalPlasma renin activitySympathetic nervous systemSerum aldosterone concentrationBody negative pressureRenin activityAldosterone concentrationBaroreflex functionBlood pressurePlasma catecholaminesOrthostatic stressHealthy blacksBlood samplesNervous systemWomenPresyncopeBaselineYoung blacksBW