2022
Subclinical cardiovascular disease and polycystic ovary syndrome
Gomez JMD, VanHise K, Stachenfeld N, Chan JL, Merz NB, Shufelt C. Subclinical cardiovascular disease and polycystic ovary syndrome. Fertility And Sterility 2022, 117: 912-923. PMID: 35512975, PMCID: PMC10322116, DOI: 10.1016/j.fertnstert.2022.02.028.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeSubclinical cardiovascular diseaseCardiovascular diseaseOvary syndromeCoronary artery calcium scoreCarotid intima-media thicknessOvert cardiovascular diseaseArtery calcium scoreFlow-mediated dilationIntima-media thicknessCalcium scoreDiabetes mellitusMetabolic syndromeArterial stiffnessIrregular mensesInsulin resistanceEpicardial fatMetabolic disordersVascular endotheliumSyndromeHallmark featureDiseaseWomenHyperandrogenismDyslipidemia
2019
Independent Effect of High Aerobic Capacity To Protect Against Diet-Induced Insulin Resistance in Male Rats
Stachenfeld NS. Independent Effect of High Aerobic Capacity To Protect Against Diet-Induced Insulin Resistance in Male Rats. Endocrinology 2019, 160: 1437-1438. PMID: 31046086, DOI: 10.1210/en.2019-00292.Commentaries, Editorials and Letters
2017
Relationship between body mass index and endothelial dysfunction in women with and without polycystic ovary syndrome
Adler T, Usselman C, Anaeto L, Schapiro R, Steele F, Toffoloni N, Takamata A, Taylor H, Stachenfeld N. Relationship between body mass index and endothelial dysfunction in women with and without polycystic ovary syndrome. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.691.8.Peer-Reviewed Original ResearchPolycystic ovary syndromeEndothelial dysfunctionOvary syndromeFlow-mediated dilation responseSympathetic nervous system activationCardiovascular disease riskBody mass indexFlow-mediated dilation (FMD) testAmerican Heart AssociationMinutes of occlusionNervous system activationRotterdam criteriaFMD responseBrachial arteryEndothelial functionEndothelial healthHealthy womenHyperemic responseMass indexSuprasystolic pressureControl womenHeart AssociationInsulin resistanceClinical indicesReproductive age
2015
Peripheral Microvascular Vasodilatory Response to Estradiol and Genistein in Women with Insulin Resistance
Wenner MM, Taylor HS, Stachenfeld NS. Peripheral Microvascular Vasodilatory Response to Estradiol and Genistein in Women with Insulin Resistance. Microcirculation 2015, 22: 391-399. PMID: 25996650, PMCID: PMC4506724, DOI: 10.1111/micc.12208.Peer-Reviewed Original ResearchConceptsL-NMMAMicrovascular vasodilationHealthy womenVasodilatory responsivenessLocal cutaneous heatingMicrovascular vasodilatory functionMicrovascular vasodilatory responsesBeat blood pressureHealthy young womenLaser Doppler flowmetryHeat-induced vasodilationMicrovascular responsivenessVascular effectsVasodilatory responseBlood pressureMicrovascular functionVasodilatory functionCutaneous heatingInsulin resistanceCutaneous circulationDoppler flowmetryGEN exposureInteraction of E2VasodilationMicrodialysis perfusion
2014
Dichotomous estradiol and genistein effects on cutaneous endothelium‐dependent vasodilation in women with and without insulin resistance (678.6)
Wenner M, Taylor H, Stachenfeld N. Dichotomous estradiol and genistein effects on cutaneous endothelium‐dependent vasodilation in women with and without insulin resistance (678.6). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.678.6.Peer-Reviewed Original ResearchEndothelial-dependent dilationInsulin-resistant womenCutaneous vascular conductanceL-NMMAHealthy womenGenistein effectsEndothelium-dependent vasodilationLaser Doppler flowmetryResistant womenVascular conductanceE2 effectsInsulin resistanceMicrodialysis infusionDependent dilationDoppler flowmetryGEN effectsWomenE2National InstituteGrant funding sourcesC heatingCVCmaxVasodilationCardioprotectionFlowmetry