2006
Effects of estradiol and medroxyprogesterone acetate on flow mediated dilation in young women
Meendering J, Torgrimson B, Kaplan P, Stachenfeld N, Minson C. Effects of estradiol and medroxyprogesterone acetate on flow mediated dilation in young women. The FASEB Journal 2006, 20: a301-a301. DOI: 10.1096/fasebj.20.4.a301-c.Peer-Reviewed Original ResearchMedroxyprogesterone acetateDay 5Day 10Gonadotropin-releasing hormone antagonistBaseline brachial artery diameterYoung womenEndothelial-dependent vasodilationBrachial artery diameterPreliminary dataMedical Research FoundationIndependent vasodilationDependent vasodilationBrachial arteryNitroglycerin administrationGnRHa administrationMPA administrationArtery diameterHormone antagonistEndogenous estrogensGnRHaVessel responsivenessDay 4Hormone treatmentAcute affectsE2
2003
Effects of estrogen and progesterone administration on extracellular fluid
Stachenfeld NS, Taylor HS. Effects of estrogen and progesterone administration on extracellular fluid. Journal Of Applied Physiology 2003, 96: 1011-1018. PMID: 14660504, DOI: 10.1152/japplphysiol.01032.2003.Peer-Reviewed Original ResearchConceptsGnRH antagonist administrationExtracellular fluid volumeGnRH antagonistEffects of estrogenAntagonist administrationPlasma volumeTranscapillary escape rateGonadotropin-releasing hormoneExtracellular fluidHealthy womenProgesterone administrationECFV expansionGanirelix acetateEndogenous estrogensStrong negative predictorDay 2Day 5Pg/AntagonistEstrogenDay 12Plasma compartmentCapillary endotheliumAdministrationProgesterone
2002
Estrogen effects on osmotic regulation of AVP and fluid balance
Stachenfeld NS, Keefe DL. Estrogen effects on osmotic regulation of AVP and fluid balance. AJP Endocrinology And Metabolism 2002, 283: e711-e721. PMID: 12217888, DOI: 10.1152/ajpendo.00192.2002.Peer-Reviewed Original ResearchConceptsHormone treatmentEstrogen effectsPlasma renin activityFree water clearanceEnd of recoveryIntrarenal effectsRenal sensitivityRenin activitySodium excretionFractional excretionAVP increaseSodium retentionFluid retentionLeuprolide acetateWater clearanceEndogenous estrogensAldosterone stimulationFluid balanceGnRHaNaCl infusionPg/EstrogenAVPProgesteroneExcretion