2013
ETA subtype receptor sensitivity to testosterone contributes to microvascular dysfunction in PCOS
Stachenfeld N, Wenner M, Taylor H. ETA subtype receptor sensitivity to testosterone contributes to microvascular dysfunction in PCOS. The FASEB Journal 2013, 27: 1133.10-1133.10. DOI: 10.1096/fasebj.27.1_supplement.1133.10.Peer-Reviewed Original ResearchPolycystic ovary syndromeCutaneous vascular conductanceHeat-induced vasodilationEndothelium-mediated vasodilationETB receptor antagonistLaser Doppler flowmetryETA blockadeTestosterone contributesEndothelial dysfunctionOvary syndromeVascular conductanceVasoconstrictor toneETA receptorsHormone antagonistReceptor antagonistMicrodialysis infusionSex hormonesDoppler flowmetryReceptor mechanismsReceptor sensitivityDay 8Day 4VasodilationDysfunctionAntagonist
2011
Sex differences in endothelial function in the microvasculature: effects of PCOS
Stachenfeld N, Wenner M, Taylor H. Sex differences in endothelial function in the microvasculature: effects of PCOS. The FASEB Journal 2011, 25: 837.2-837.2. DOI: 10.1096/fasebj.25.1_supplement.837.2.Peer-Reviewed Original ResearchPolycystic ovary syndromeETB receptorsEffects of PCOSHeart disease riskLaser Doppler flowmetrySkin blood flowNormal reproductive functionDose-response curveEndothelial dysfunctionOvary syndromeVasoconstrictive responseVasodilatory responseEndothelial functionCutaneous microvasculatureETA receptorsHealthy womenAntagonist infusionDoppler flowmetrySmooth muscleBlood flowReceptor AReproductive functionDisease riskWomenReceptors