2010
Greater Exercise Sweating in Obese Women with Polycystic Ovary Syndrome Compared with Obese Controls
STACHENFELD NS, YECKEL CW, TAYLOR HS. Greater Exercise Sweating in Obese Women with Polycystic Ovary Syndrome Compared with Obese Controls. Medicine & Science In Sports & Exercise 2010, 42: 1660-1668. PMID: 20195177, PMCID: PMC3109293, DOI: 10.1249/mss.0b013e3181d8cf68.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromePCOS groupOvary syndromeControl groupGonadotropin-releasing hormone antagonistObese controlsObese womenAge-predicted HRmaxCore temperature thresholdHormone antagonistTestosterone effectsDay 4GnRHantSweat volumeDay 13Total sweat lossHormone conditionsWomenSweatingE2Sweat lossSyndromeEstradiolTestosteroneThermoregulatory responsesPeripheral microvascular responses to norepinephrine in women with orthostatic intolerance
Wenner M, Taylor H, Stachenfeld N. Peripheral microvascular responses to norepinephrine in women with orthostatic intolerance. The FASEB Journal 2010, 24: 991.17-991.17. DOI: 10.1096/fasebj.24.1_supplement.991.17.Peer-Reviewed Original ResearchCumulative stress indexVasoconstrictor responsesAdrenergic responseMaximal lower body negative pressureLower body negative pressurePeripheral microvascular responseEffects of estradiolBody negative pressureFemale sex hormonesSkin blood flowEndogenous E2GnRH antagonistNE infusionDaily administrationMicrovascular responsesCutaneous microvasculatureOrthostatic intoleranceOrthostatic toleranceSex hormonesBlood flowSkin microvasculatureAdrenergic stimulationDay 4Hormone treatmentDay 13
2009
Sex hormone effects on body fluid and sodium regulation in women with and without exercise-associated hyponatremia
Stachenfeld NS, Taylor HS. Sex hormone effects on body fluid and sodium regulation in women with and without exercise-associated hyponatremia. Journal Of Applied Physiology 2009, 107: 864-872. PMID: 19556454, DOI: 10.1152/japplphysiol.91211.2008.Peer-Reviewed Original ResearchConceptsExercise-associated hyponatremiaSodium lossGonadotropin-releasing hormone antagonistPeak oxygen consumptionMin of exerciseHistory of hyponatremiaHigh water intakeGnRH-antFluid retentionHormone antagonistProgesterone exposureEndurance exerciseDay 4Hormone effectsDay 13HyponatremiaSodium regulationHormone conditionsWomenHypoWater intakeOxygen consumptionProgesteroneExerciseLittle fallFEMALE REPRODUCTIVE HORMONE EFFECTS ON SKIN VESSEL ADRENERGIC RESPONSIVENESS IN WOMEN WITH LOW AND HIGH ORTHOSTATIC TOLERANCE.
Stachenfeld N, Hinds K, Taylor H. FEMALE REPRODUCTIVE HORMONE EFFECTS ON SKIN VESSEL ADRENERGIC RESPONSIVENESS IN WOMEN WITH LOW AND HIGH ORTHOSTATIC TOLERANCE. The FASEB Journal 2009, 23: 968.2-968.2. DOI: 10.1096/fasebj.23.1_supplement.968.2.Peer-Reviewed Original ResearchHigh orthostatic toleranceCumulative stress indexL-NMMAAdrenergic responsivenessOrthostatic toleranceLower body negative pressureReproductive hormone effectsNitric oxide mechanismBody negative pressureLaser Doppler flowmetrySkin blood flowStimulus-response curvesNorepinephrine infusionHormone antagonistDoppler flowmetryBlood flowDay 4Hormone effectsDay 13GnRHProgesteroneOxide mechanismWomenEstradiolResponsiveness
2007
Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women
Stachenfeld NS, Taylor HS. Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women. Clinical Endocrinology 2007, 66: 410-418. PMID: 17302877, DOI: 10.1111/j.1365-2265.2007.02748.x.Peer-Reviewed Original ResearchConceptsExtracellular fluid volumeTranscapillary albumin escape rateGonadotropin-releasing hormone antagonistPmol/Plasma renin activitySerum aldosterone concentrationHealthy young womenAlbumin escape rateRenin activityAldosterone concentrationGnRH antagonistHealthy womenProgesterone administrationExogenous oestradiolIntravascular volumeHormone antagonistProgesterone increaseDay 2Day 5Hormone treatmentOestradiolDay 13Extravascular componentOncotic pressureYoung women
2005
Progesterone increases plasma volume independent of estradiol
Stachenfeld NS, Taylor HS. Progesterone increases plasma volume independent of estradiol. Journal Of Applied Physiology 2005, 98: 1991-1997. PMID: 15718411, DOI: 10.1152/japplphysiol.00031.2005.Peer-Reviewed Original ResearchConceptsTranscapillary escape ratePlasma concentrationsPlasma volumeGnRH antagonistECF volumeAdequate plasma volumeAldosterone system stimulationPlasma renin activityGonadotropin-releasing hormoneExtracellular fluid volumeRenin activitySerum aldosteroneAng IIBlood pressureEstrogen administrationSystem stimulationDay 2Day 5Pg/Day 13Fluid regulationPV expansionFluid volumeIndependent effectsProgesterone