2024
The effect of acute estrogen suppression on cutaneous endothelium-dependent vasodilation in women with endometriosis
Colburn A, Leone C, Alexander L, Stachenfeld N. The effect of acute estrogen suppression on cutaneous endothelium-dependent vasodilation in women with endometriosis. Physiology 2024, 39: 421. DOI: 10.1152/physiol.2024.39.s1.421.Peer-Reviewed Original ResearchEndothelium-dependent vasodilationEstrogen suppressionHealthy controlsLDF/mean arterial pressureSodium nitroprusside perfusionDose-response curveLaser Doppler flowmetryCardiovascular disease riskCutaneous vascular conductanceACh doseEndometriosis patientsPerfusion of acetylcholineMenstrual cycleIntradermal microdialysisSuppress estrogenEndothelial functionArterial pressureEndometriosisVasodilatory functionDoppler flowmetryVascular conductanceVasodilationMaximal vasodilationGraded perfusionEstrogen
2022
Sympathetic Responses to Isometric Handgrip Exercise in Women following Preeclamptic Pregnancies
Orr H, Adler T, Leone C, Paidas M, Stachenfeld N, Usselman C. Sympathetic Responses to Isometric Handgrip Exercise in Women following Preeclamptic Pregnancies. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r4218.Peer-Reviewed Original ResearchMuscle sympathetic nerve activityPost-exercise circulatory occlusionHand-grip exerciseElevated muscle sympathetic nerve activityHP womenMSNA responsesPreeclamptic pregnanciesBaseline muscle sympathetic nerve activityIsometric hand-grip exerciseSympathetic nerve activityIsometric handgrip exerciseTotal peripheral resistanceHG exerciseSympathetic dysregulationCardiovascular outcomesCirculatory occlusionHandgrip exerciseArterial pressureHealthy pregnancyNerve activityPE pregnanciesPeripheral resistanceGrip exercisePE womenCardiovascular disease
2018
Sympathetic Nervous System Reactivity in Women following Preeclamptic Pregnancies
Usselman C, Adler T, Leone C, Paidas M, Stachenfeld N. Sympathetic Nervous System Reactivity in Women following Preeclamptic Pregnancies. The FASEB Journal 2018, 32: 714.7-714.7. DOI: 10.1096/fasebj.2018.32.1_supplement.714.7.Peer-Reviewed Original ResearchMuscle sympathetic nerve activityPreeclamptic pregnanciesWomen 6Cardiovascular diseaseBaseline muscle sympathetic nerve activitySympathetic nervous system dysregulationBaseline mean arterial pressureSympathetic nervous system responsesSympathetic nerve activityHistory of preeclampsiaMean arterial pressureTotal peripheral resistanceSympathetic nervous system reactivityChronic sympathetic activationDepartment of ObstetricsSympathetic nervous systemLife-long riskNervous system dysregulationNervous system responsesGreater sympathetic reactivityFull-text articlesChemoreflex stressMSNA responsesPreeclamptic womenArterial pressure
1997
Mechanism of attenuated thirst in aging: role of central volume receptors
Stachenfeld N, DiPietro L, Nadel E, Mack G. Mechanism of attenuated thirst in aging: role of central volume receptors. American Journal Of Physiology 1997, 272: r148-r157. PMID: 9039003, DOI: 10.1152/ajpregu.1997.272.1.r148.Peer-Reviewed Original ResearchConceptsCentral blood volume expansionBlood volume expansionYoung subjectsOlder subjectsPlasma volumePlasma atrial natriuretic peptide concentrationAtrial natriuretic peptide concentrationsThirst ratingsOlder peopleFractional sodium excretionPlasma renin activityArterial blood pressureNatriuretic peptide concentrationsCentral volume expansionMin of headWater perfusion suitAd libitum water intakeAldosterone concentrationRenin activitySodium excretionArterial baroreceptorsArterial pressureBlood pressureRenal responseVolume receptors