2010
Greater Orthostatic Tolerance in Young Black Compared With White Women
Hinds K, Stachenfeld NS. Greater Orthostatic Tolerance in Young Black Compared With White Women. Hypertension 2010, 56: 75-81. PMID: 20458005, PMCID: PMC2909588, DOI: 10.1161/hypertensionaha.110.150011.Peer-Reviewed Original ResearchConceptsLower body negative pressureBody negative pressureOrthostatic toleranceWhite womenHeart rateGreater sympathetic nervous system responseR intervalSympathetic nervous system responsesPlasma renin activityPlasma catecholamine concentrationsSerum aldosterone concentrationNervous system responsesNegative pressureBlack womenCumulative stress indexWoman underwentRenin activityAldosterone concentrationBaroreflex functionBlood pressureCatecholamine concentrationsOrthostatic challengePlasma concentrationsHealthy blacksBlood samplesGreater orthostatic tolerance in young black compared to white women
Hinds K, Stachenfeld N. Greater orthostatic tolerance in young black compared to white women. The FASEB Journal 2010, 24: 977.9-977.9. DOI: 10.1096/fasebj.24.1_supplement.977.9.Peer-Reviewed Original ResearchLower body negative pressureOrthostatic toleranceWhite womenCumulative stress indexHeart rateLevels of LBNPR intervalPlasma renin activitySympathetic nervous systemSerum aldosterone concentrationBody negative pressureRenin activityAldosterone concentrationBaroreflex functionBlood pressurePlasma catecholaminesOrthostatic stressHealthy blacksBlood samplesNervous systemWomenPresyncopeBaselineYoung blacksBW
2007
Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women
Stachenfeld NS, Taylor HS. Exogenous oestradiol and progesterone administration does not cause oedema in healthy young women. Clinical Endocrinology 2007, 66: 410-418. PMID: 17302877, DOI: 10.1111/j.1365-2265.2007.02748.x.Peer-Reviewed Original ResearchConceptsExtracellular fluid volumeTranscapillary albumin escape rateGonadotropin-releasing hormone antagonistPmol/Plasma renin activitySerum aldosterone concentrationHealthy young womenAlbumin escape rateRenin activityAldosterone concentrationGnRH antagonistHealthy womenProgesterone administrationExogenous oestradiolIntravascular volumeHormone antagonistProgesterone increaseDay 2Day 5Hormone treatmentOestradiolDay 13Extravascular componentOncotic pressureYoung women
1998
Estrogen influences osmotic secretion of AVP and body water balance in postmenopausal women
Stachenfeld N, Dipietro L, Palter S, Nadel E. Estrogen influences osmotic secretion of AVP and body water balance in postmenopausal women. American Journal Of Physiology 1998, 274: r187-r195. PMID: 9458917, DOI: 10.1152/ajpregu.1998.274.1.r187.Peer-Reviewed Original ResearchConceptsMin of drinkingPg/Body water balanceHypertonic salineFractional sodium excretionPlasma aldosterone concentrationRenal sodium reabsorptionFree water clearancePlasma estradiol concentrationsHypertonic saline infusionHigh E2 statesWater ad libitumMosmol/kgH2OAldosterone concentrationPostmenopausal womenSodium excretionPlacebo administrationUrine outputAVP secretionSodium reabsorptionFluid retentionE2 treatmentEstradiol concentrationsWater clearanceSaline infusion
1997
Mechanism of attenuated thirst in aging: role of central volume receptors
Stachenfeld N, DiPietro L, Nadel E, Mack G. Mechanism of attenuated thirst in aging: role of central volume receptors. American Journal Of Physiology 1997, 272: r148-r157. PMID: 9039003, DOI: 10.1152/ajpregu.1997.272.1.r148.Peer-Reviewed Original ResearchConceptsCentral blood volume expansionBlood volume expansionYoung subjectsOlder subjectsPlasma volumePlasma atrial natriuretic peptide concentrationAtrial natriuretic peptide concentrationsThirst ratingsOlder peopleFractional sodium excretionPlasma renin activityArterial blood pressureNatriuretic peptide concentrationsCentral volume expansionMin of headWater perfusion suitAd libitum water intakeAldosterone concentrationRenin activitySodium excretionArterial baroreceptorsArterial pressureBlood pressureRenal responseVolume receptors