2021
Perianeurysmal retroperitoneal fibrosis presenting as acute kidney injury: A case report.
Hodson DZ, Cantley LG, Perincheri S, Singh N. Perianeurysmal retroperitoneal fibrosis presenting as acute kidney injury: A case report. Clinical Nephrology 2021, 96: 112-119. PMID: 34142944, DOI: 10.5414/cn110331.Peer-Reviewed Case Reports and Technical NotesConceptsAcute kidney injuryKidney injuryChronic periaortitisRenal functionRetroperitoneal fibrosisLong-term renal functionRetroperitoneal soft tissue massPerianeurysmal retroperitoneal fibrosisAcute tubular injuryLong-term sequelaeBilateral nephrostomy tubesInfrarenal abdominal aortaSoft tissue massBilateral uretersRenal ultrasoundCommon complicationOlder patientsRenal failureTubular injuryUltrasonographic evidenceUncommon causeRenal biopsyRenal sonographyFirst admissionObstructive nephropathyTubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function
Avigan ZM, Singh N, Kliegel JA, Weiss M, Moeckel GW, Cantley LG. Tubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function. Transplantation Direct 2021, 7: e716. PMID: 34476295, PMCID: PMC8384397, DOI: 10.1097/txd.0000000000001168.Peer-Reviewed Original ResearchDeceased donor kidney transplantDonor biopsiesGraft functionTubular injuryTubular cellsDelayed graft functionAcute tubular injuryDonor kidney transplantsConventional histopathologic evaluationPotential therapeutic interventionsMass cytometry analysisTubular cell lossDGF riskGraft outcomeTransplant recipientsKidney transplantPharmacologic therapyDeceased donorsMacrophage infiltrationHistopathologic evaluationLiving donorsDonor factorsCold ischemiaHistopathologic analysisCell dropout
2019
Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis
Moledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Kashgarian M, Cantley LG, Parikh CR. Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis. JCI Insight 2019, 4: e127456. PMID: 31092735, PMCID: PMC6542610, DOI: 10.1172/jci.insight.127456.Peer-Reviewed Original ResearchConceptsAcute interstitial nephritisAcute kidney diseasePrebiopsy diagnosisKidney biopsyKidney diseaseIL-9AIN diagnosisUrine TNFInterstitial nephritisSpecific T cell subsetsAcute tubular injuryDiabetic kidney diseaseIL-9 levelsTNF-α levelsT cell subsetsAddition of biomarkersPlasma cytokinesCytokine levelsTubular injuryHighest quartileMultivariable analysisCell subsetsUrinary TNFBlood eosinophilsGlomerular disease