Racial and Age-Related Differences in Impacts of High-Risk Cytogenetic Abnormalities on Survival in Multiple Myeloma in a Nationwide Electronic Health Record-Derived Database
Calip G, Ascha M, Wang X, Pierre A, Maignan K, Wadé N, Leng S, Seymour E, Chiu B, Sweiss K, Patel P, Neparidze N. Racial and Age-Related Differences in Impacts of High-Risk Cytogenetic Abnormalities on Survival in Multiple Myeloma in a Nationwide Electronic Health Record-Derived Database. Blood 2021, 138: 4121. DOI: 10.1182/blood-2021-152774.Peer-Reviewed Original ResearchReal-world progression-free survivalHigh-risk cytogenetic abnormalitiesCurrent equity holderFlatiron HealthBlack patientsWhite patientsMultiple myelomaMM patientsCytogenetic abnormalitiesClinical characteristicsHazard ratioAge groupsAutologous stem cell transplantationAdvisory CommitteeAdult MM patientsCytogenetic risk stratificationOlder black patientsTechnology-enabled abstractionYoung black patientsAdjusted hazard ratioRetrospective cohort studyFirst-line therapyFirst-line treatmentHigh-risk subsetProgression-free survival