2012
Comparative Effects of Angiotensin Receptor Blockade and ACE Inhibition on the Fibrinolytic and Inflammatory Responses to Cardiopulmonary Bypass
Billings F, Balaguer J, Yu C, Wright P, Petracek M, Byrne J, Brown N, Pretorius M. Comparative Effects of Angiotensin Receptor Blockade and ACE Inhibition on the Fibrinolytic and Inflammatory Responses to Cardiopulmonary Bypass. Clinical Pharmacology & Therapeutics 2012, 91: 1065-1073. PMID: 22549281, PMCID: PMC3822756, DOI: 10.1038/clpt.2011.356.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiotensin II Type 1 Receptor BlockersAngiotensin-Converting Enzyme InhibitorsBenzimidazolesBiphenyl CompoundsBlood TransfusionBradykininCardiopulmonary BypassEndpoint DeterminationFemaleFibrinolysisHematocritHospital MortalityHumansInflammationInterleukinsLength of StayMaleMiddle AgedMonitoring, IntraoperativePerioperative CarePostoperative ComplicationsRamiprilTetrazolesTreatment OutcomeConceptsAngiotensin II type 1 receptor blockadeACE inhibitionCardiopulmonary bypassReceptor blockadeInflammatory responseType 1 receptor blockadeTissue-type plasminogen activator concentrationAngiotensin receptor blockadeEffect of angiotensinRed cell transfusionDay of surgeryPlasminogen activator inhibitor-1Activator inhibitor-1Plasminogen activator concentrationsHospital stayPlasma transfusionIL-10ACE inhibitorsIL-8Intraoperative fibrinolysisFibrinolysisInhibitor-1Comparative effectsPlaceboTransfusion
2008
Milrinone Use Is Associated With Postoperative Atrial Fibrillation After Cardiac Surgery
Fleming GA, Murray KT, Yu C, Byrne JG, Greelish JP, Petracek MR, Hoff SJ, Ball SK, Brown NJ, Pretorius M. Milrinone Use Is Associated With Postoperative Atrial Fibrillation After Cardiac Surgery. Circulation 2008, 118: 1619-1625. PMID: 18824641, PMCID: PMC2770257, DOI: 10.1161/circulationaha.108.790162.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCardiac Surgical ProceduresCardiotonic AgentsCoronary DiseaseElective Surgical ProceduresFemaleHumansHypertensionLength of StayLogistic ModelsMaleMiddle AgedMilrinoneMitral Valve InsufficiencyMultivariate AnalysisPostoperative ComplicationsPulmonary Wedge PressureRisk FactorsConceptsPostoperative atrial fibrillationPulmonary artery pressureElective cardiac surgeryMilrinone useMitral valve surgeryAtrial fibrillationCardiac surgeryArtery pressureValve surgeryInotropic drugsEjection fractionRisk factorsLow preoperative ejection fractionHigh pulmonary artery pressurePerioperative risk factorsPreoperative ejection fractionRight ventricular dysfunctionIndependent risk factorPulmonary artery catheterMultivariable logistic regressionProlong hospitalizationVentricular dysfunctionArtery catheterFrequent complicationVentricular function
2006
Risk factor interactions and genetic effects associated with post-operative atrial fibrillation.
Motsinger AA, Donahue BS, Brown NJ, Roden DM, Ritchie MD. Risk factor interactions and genetic effects associated with post-operative atrial fibrillation. Biocomputing 2006, 584-95. PMID: 17094271.Peer-Reviewed Original ResearchConceptsDevelopment of PoAFPostoperative atrial fibrillationAtrial fibrillationDisease statusPost-operative atrial fibrillationHistory of AFRisk factor interactionsGenetic risk factorsPOAF riskHospital stayClinical factorsGeneral anesthesiaCommon arrhythmiaHeart surgeryIL-6Elective proceduresRisk factorsAF casesGreat vesselsGene-environment interactionsPoAFPotential associationAdult subjectsTotal sample sizeFibrillation