Featured Publications
ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting
Zwolinski N, Patel K, Vadivelu N, Kodumudi G, Kaye A. ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting. Current Pain And Headache Reports 2023, 27: 65-79. PMID: 37079258, PMCID: PMC10116112, DOI: 10.1007/s11916-023-01108-3.Peer-Reviewed Original ResearchConceptsSubstance use disordersSubstance use disorder patientsAmbulatory patientsUse disordersDisorder patientsERAS protocolPerioperative pain managementAmbulatory surgery settingHospital quality metricsAmbulatory surgical settingAmbulatory surgery casesPerioperative protocolPain managementAdverse outcomesAmbulatory surgeryPharmacodynamic profileSurgery settingAmbulatory proceduresSurgery casesClinical dataEarly recoveryAbused substancesSurgical settingPatientsSubspecialty groupsKetamine
Shergill S, Vadivelu N. Ketamine. 2023, 195-205. DOI: 10.1007/978-3-031-21291-8_13.Peer-Reviewed Original ResearchPost-operative pain controlPost-operative analgesiaSympathetic nervous systemMaintenance of anesthesiaMultiple surgical proceduresMu-opioid receptorsNMDA receptor antagonismComplete anestheticERAS protocolOperative analgesiaAnalgesic benefitPain controlPulmonary diseaseSeptic shockChronic painReceptor antagonismSubanesthetic dosesOpioid receptorsPotent analgesicSurgical proceduresHepatic enzymesNervous systemPartial agonistKetaminePatientsAnticonvulsants
Popovitz E, Li J, Vadivelu N. Anticonvulsants. 2023, 139-146. DOI: 10.1007/978-3-031-21291-8_9.ChaptersDiabetic peripheral neuropathySpinal cord injuryPerioperative settingRole of anticonvulsantsHerpetic neuralgiaMultimodal analgesiaNeuropathic painSurgery protocolPeripheral neuropathyCord injuryPrimary medicationThoracic proceduresAssociated pathologyEnhanced recoveryAnalgesiaNeuropathyPainAnticonvulsantsOptimal dosageGabapentinoidsNeuralgiaMedicationsHIVGabapentinPregabalinFifty years of ambulatory anaesthesia: Stepping out and stepping forward!
Mitra S, Arora S, Vadivelu N. Fifty years of ambulatory anaesthesia: Stepping out and stepping forward! Indian Journal Of Anaesthesia 2024, 68: 320-322. PMID: 38586261, PMCID: PMC10993947, DOI: 10.4103/ija.ija_857_23.Peer-Reviewed Original ResearchEvolving Therapeutic Roles of Nasogastric Tubes: Current Concepts in Clinical Practice
Vadivelu N, Kodumudi G, Leffert L, Pierson D, Rein L, Silverman M, Cornett E, Kaye A. Evolving Therapeutic Roles of Nasogastric Tubes: Current Concepts in Clinical Practice. Advances In Therapy 2023, 40: 828-843. PMID: 36637690, PMCID: PMC9838367, DOI: 10.1007/s12325-022-02406-9.Peer-Reviewed Original ResearchConceptsNasogastric tubeShort-term parenteral nutritionTerm parenteral nutritionManagement of complicationsAdministration of medicationsMultiple medical specialtiesTechnique of insertionResuscitative toolBowel obstructionParenteral nutritionChronic careTherapeutic roleClinical practiceComplicationsSurgical specialtiesCurrent conceptsMedical specialtiesRecent updatesCorrect positioningSpecialtiesContraindicationsMedicationsObstructionStomachAdministrationEnhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review
Rajput K, Shergill S, Chow RM, Vadivelu N, Kaye AD. Enhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review. Current Pain And Headache Reports 2022, 26: 93-102. PMID: 35072920, DOI: 10.1007/s11916-022-01009-x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid usePersistent post-surgical painNon-opioid strategiesNon-opioid therapiesOpioid-sparing strategiesOverprescribing of opioidsPostoperative pain scoresMultimodal analgesic approachPost-surgical painSide effect profileNon-opioid analgesicsRecent FindingsSeveral studiesERAS protocolOpioid protocolAnalgesic approachBreakthrough painHospital stayMultimodal analgesiaPain scoresAcute painOral ketaminePostoperative periodEffect profilePatient recoveryGood quality researchAmbulatory Pain Management in the Pediatric Patient Population
Oliver JA, Oliver LA, Aggarwal N, Baldev K, Wood M, Makusha L, Vadivelu N, Lichtor L. Ambulatory Pain Management in the Pediatric Patient Population. Current Pain And Headache Reports 2022, 26: 15-23. PMID: 35129824, DOI: 10.1007/s11916-022-00999-y.Peer-Reviewed Original ResearchConceptsPain managementPostoperative painPediatric ambulatory surgical patientsPostoperative pain controlAmbulatory surgical patientsSevere postoperative painExtent of painPeripheral nerve blocksPediatric ambulatory surgeryPediatric patient populationNon-pharmacological techniquesRandomized control studyEvidence-based approachMultimodal analgesiaPain controlSurgical patientsNerve blockPediatric populationAmbulatory surgeryPatient populationMost centersControl studyPainScientific evidenceMultimodal approachAnalgesia for Gynecologic Oncologic Surgeries: A Narrative Review
Patel K, Shergill S, Vadivelu N, Rajput K. Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review. Current Pain And Headache Reports 2022, 26: 1-13. PMID: 35118596, DOI: 10.1007/s11916-022-00998-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHyperthermic intraperitoneal chemotherapyCytoreductive surgeryPain managementNarrative reviewOptimal perioperative pain managementGynecologic oncologic surgeryPerioperative analgesic planPostoperative pain managementPerioperative pain managementLocal anesthetic infiltrationInvasive cancer surgeryMultimodal analgesicsPreemptive analgesiaMultimodal analgesiaPostoperative painAnalgesic planAnesthetic infiltrationGynecologic malignanciesIntraperitoneal chemotherapyPerioperative periodSurgery protocolThoracic epiduralCancer surgeryChronic painNeuraxial techniquesWeaning Protocols After Ambulatory Surgery
Aggarwal N, Zafar J, Kodumudi G, Vadivelu N, Laurans M, Rajput K. Weaning Protocols After Ambulatory Surgery. 2021, 369-377. DOI: 10.1007/978-3-030-55262-6_28.ChaptersHospital-based outpatient departmentsAmbulatory surgery centersPostoperative painUnplanned admissionsAmbulatory surgeryLong-term opioid usersNumber of surgeriesUnanticipated admissionMultimodal analgesiaOpioid prescriptionsPain medicationPerioperative analgesiaIntractable nauseaOutpatient departmentOpioid usersAmbulatory proceduresSurgery centersWeaning protocolHospital careOrthopedic proceduresSurgeryPainPatientsAdmissionMajor causeSpecial Considerations – Indwelling Spinal Cord Stimulators and Intrathecal Pumps
Beals C, Chow R, Vadivelu N, Rajput K. Special Considerations – Indwelling Spinal Cord Stimulators and Intrathecal Pumps. 2021, 335-343. DOI: 10.1007/978-3-030-55262-6_25.ChaptersSpinal cord stimulatorContinuous opioid useChronic pain patientsPaucity of literatureIT clonidineCentral sensitizationMultimodal analgesiaSystemic medicationsOpioid toleranceOpioid usePerioperative managementPain patientsPain physiciansPump dysfunctionIntrathecal pumpNeuraxial anesthesiaAmbulatory surgeryLong actingRegional anesthesiaPatientsSurgeryUnique subsetNormal functionAnesthesiaStimulatorNovel Regional Anesthesia for Outpatient Surgery
Li J, Lam D, King H, Credaroli E, Harmon E, Vadivelu N. Novel Regional Anesthesia for Outpatient Surgery. Current Pain And Headache Reports 2019, 23: 69. PMID: 31372836, DOI: 10.1007/s11916-019-0809-6.Peer-Reviewed Original ResearchConceptsNerve blockAdverse eventsOutpatient surgeryLower extremity nerve blocksPeripheral nerve blocksPotential adverse eventsProper patient managementPerioperative analgesiaAmbulatory surgerySafe modalityShoulder surgeryAmbulatory proceduresRegional anesthesiaPatient managementUltrasound guidanceProper patientLower riskSurgeryPatient choiceMultidisciplinary effortAnalgesiaAnesthesiaPatientsUltrasound for peripheral and arterial access
Oliver LA, Oliver JA, Ohanyan S, Park W, Benelyahoo A, Vadivelu N. Ultrasound for peripheral and arterial access. Best Practice & Research Clinical Anaesthesiology 2019, 33: 523-537. PMID: 31791568, DOI: 10.1016/j.bpa.2019.10.002.Peer-Reviewed Original ResearchConceptsHealth care professionalsArterial accessCare professionalsNumerous patient factorsChronic kidney diseasePeripheral intravenous accessPeripheral venous accessSkilled health care professionalsArterial line placementStandard landmark techniqueIntravenous accessPatient factorsAccess placementVenous accessKidney diseasePatient populationVascular accessSurgical centersUltrasound guidanceUrgent careLandmark techniqueLine placementDrug useBlood vesselsSuccess rateEndometriosis Pain Management: a Review
Carlyle D, Khader T, Lam D, Vadivelu N, Shiwlochan D, Yonghee C. Endometriosis Pain Management: a Review. Current Pain And Headache Reports 2020, 24: 49. PMID: 32671581, DOI: 10.1007/s11916-020-00884-6.Peer-Reviewed Original ResearchConceptsSurgical managementGnRH agonists/antagonistsNonsteroidal anti-inflammatory drugsPain management optionsAnti-inflammatory drugsAgonists/antagonistsNerve ablationPresacral neurectomyMedical managementTreatment modalitiesAromatase inhibitorsChallenging diseaseSurgical techniqueReviewThe purposeNeurectomyExperimental pharmaceuticalsManagement optionsAblationHysterectomyOophorectomyEndometriosisRegimensResectionDanazolPatientsUltrasound-Guided Neuraxial Anesthesia
Li J, Krishna R, Zhang Y, Lam D, Vadivelu N. Ultrasound-Guided Neuraxial Anesthesia. Current Pain And Headache Reports 2020, 24: 59. PMID: 32812182, DOI: 10.1007/s11916-020-00895-3.Peer-Reviewed Original ResearchConceptsNeuraxial anesthesiaHigher first-attempt success rateFirst-attempt success rateNon-obstetric patientsAcute pain managementAttempt success ratePurpose of ReviewTherePain managementRegional anesthesiaNeuraxial spacePatient safety implicationsVertebral levelAnesthesiaOverall efficacyRecent FindingsUltrasoundNeedle passPatient safetyCatheter visualizationUltrasound utilizationClinical accuracySuccess rateCommon typeClinical applicationUltrasoundPatientsCommon Congenital Syndromes and Disease States Impacting Regional Anesthesiology Techniques
Thomas D, Missih O, Zhu R, Suchy T, Vadivelu N. Common Congenital Syndromes and Disease States Impacting Regional Anesthesiology Techniques. 2020, 111-122. DOI: 10.1007/978-3-030-55660-0_6.ChaptersHigh riskCommon congenital syndromeLimited neck mobilityTurner syndromeBicuspid aortic valveRisk of aspirationType 2 diabetesIntraoperative hypertensionLiver dysfunctionAortic dissectionHearing changesKidney functionHorseshoe kidneyInsulin resistanceNeck mobilityAortic valveAnesthesiology techniquesArched palateCongenital syndromeMaxillary hypoplasiaAnatomic differencesCognitive impairmentNormal tracheaKidney abnormalitiesShort statureAcute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers
Rajput K, Vadivelu N. Acute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers. Current Pain And Headache Reports 2021, 25: 1. PMID: 33443656, DOI: 10.1007/s11916-020-00922-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPerioperative pain managementAmbulatory surgery centersNon-opioid analgesicsPain managementSurgery centersIntrathecal pain pumpOpioid-tolerant patientsPostoperative opioid requirementsAcute pain managementChronic opioid useProportion of patientsSubset of patientsChronic pain patientsSame-day admission patientsSpinal cord stimulatorPurpose of ReviewWithOpioid requirementsPostoperative opioidsMalignant painMultimodal analgesiaPerioperative painOpioid toleranceOpioid usePain specialistsPain patientsUltrasound Guided Brachial Plexus Block
Li J, Sharma A, Credaroli E, Vadivelu N, Liu H. Ultrasound Guided Brachial Plexus Block. 2021, 121-128. DOI: 10.1007/978-3-030-46839-2_13.ChaptersLocal anesthetic systemic toxicityReal-time ultrasound guidanceFaster block onsetBrachial plexus blockBrachial plexus blockadeUpper extremity blocksEntire upper extremityUpper extremity proceduresOpioid reductionOpioid sparingBlock successExcellent analgesiaPlexus blockPlexus blockadeCervical plexusNerve stimulationGeneral anesthesiaBrachial plexusExtremity proceduresUpper extremityRegional anesthesiaSurgical anesthesiaIntravascular injectionUltrasound guidanceLandmark techniqueCurrent US Policy for Opioid Prescribing
Shah A, Haddad D, Vadivelu N, Rajput K. Current US Policy for Opioid Prescribing. 2021, 29-41. DOI: 10.1007/978-3-030-55262-6_3.ChaptersRecent policy initiativesLate nineteenth-century United StatesCurrent US policyNineteenth-century United StatesUnited StatesUS policyPolicy initiativesPresent-day roleNumerous federal regulationsLocal levelFederal initiativesOpioid policyIndividual statesMedical practice standardsHistorical groundworkPolicyDisciplinary actionBest practicesRegulatory bodiesInitiativesPrescription drug monitoring programsState medical boardsOpioid-related harmsFederal regulationsPrescription opioid epidemicRecovery Room Protocols for Nursing in Ambulatory Surgery Centers (ASCs) and Hospital Outpatient Departments (HOPDs)
Zafar J, Vadivelu N, Rajput K, Fontanez P. Recovery Room Protocols for Nursing in Ambulatory Surgery Centers (ASCs) and Hospital Outpatient Departments (HOPDs). 2021, 355-367. DOI: 10.1007/978-3-030-55262-6_27.ChaptersHospital outpatient departmentsAmbulatory surgery centersQuality of carePostoperative nauseaAdverse cardiac eventsFast-track protocolPain management protocolPain assessment scalesEvidence-based guidelinesLength of stayHypothermia protocolUnplanned admissionsCardiac eventsNursing protocolNurse assessmentPain managementRecovery roomOutpatient departmentStandardization of practiceOutpatient surgerySurgery centersCommon causeAmbulatory settingMultidisciplinary teamAssessment ScaleAnalysis of Multiple Routes of Analgesic Administration in the Immediate Postoperative Period: a 10-Year Experience
Vadivelu N, Kai AM, Dai F, Dabu-Bondoc S. Analysis of Multiple Routes of Analgesic Administration in the Immediate Postoperative Period: a 10-Year Experience. Current Pain And Headache Reports 2019, 23: 22. PMID: 30854578, DOI: 10.1007/s11916-019-0754-4.Peer-Reviewed Original ResearchConceptsPain scoresAnalgesic administrationPostoperative painPost-anesthesia care unitYale-New Haven HospitalImmediate postoperative painPostoperative pain scoresPurpose of ReviewAnSignificant pain reliefImmediate postoperative periodConsecutive surgical casesTime of dischargeRoute of administrationCommon routeAdverse side effectsNew Haven HospitalIndividual analgesicsNeuraxial routeAnalgesia administrationNeuraxial analgesiaPain reliefPostoperative periodSynergistic analgesiaCare unitParenteral route