Featured Publications
Anticonvulsants
Popovitz E, Li J, Vadivelu N. Anticonvulsants. 2023, 139-146. DOI: 10.1007/978-3-031-21291-8_9.ChaptersDiabetic peripheral neuropathySpinal cord injuryPerioperative settingRole of anticonvulsantsHerpetic neuralgiaMultimodal analgesiaNeuropathic painSurgery protocolPeripheral neuropathyCord injuryPrimary medicationThoracic proceduresAssociated pathologyEnhanced recoveryAnalgesiaNeuropathyPainAnticonvulsantsOptimal dosageGabapentinoidsNeuralgiaMedicationsHIVGabapentinPregabalin
2016
Facial Pain Update: Advances in Neurostimulation for the Treatment of Facial Pain
Maniam R, Kaye AD, Vadivelu N, Urman RD. Facial Pain Update: Advances in Neurostimulation for the Treatment of Facial Pain. Current Pain And Headache Reports 2016, 20: 24. PMID: 26896948, DOI: 10.1007/s11916-016-0553-0.Peer-Reviewed Original ResearchConceptsInterventional pain proceduresCraniofacial painFacial painPharmacological therapyPain proceduresHigh-frequency spinal cord stimulationPersistent idiopathic facial painPeripheral nerve field stimulationIdiopathic facial painInterventional pain techniquesSphenopalatine ganglion stimulationTrigeminal neuropathic painTraditional pharmacological therapyInterventional pain therapySmall patient cohortSpinal cord stimulationDeep brain stimulationInvasive implantation techniquesGanglion stimulationNeuropathic painPain statesPain therapyTrigeminal neuralgiaCord stimulationPatient cohort
2015
Tapentadol extended release in the management of peripheral diabetic neuropathic pain
Vadivelu N, Kai A, Maslin B, Kodumudi G, Legler A, Berger JM. Tapentadol extended release in the management of peripheral diabetic neuropathic pain. Therapeutics And Clinical Risk Management 2015, Volume 11: 95-105. PMID: 25609974, PMCID: PMC4298300, DOI: 10.2147/tcrm.s32193.Peer-Reviewed Original ResearchPainful diabetic neuropathyDiabetic neuropathyOpioid-based therapyCancer-related painDiabetic neuropathic painChronic pain conditionsGastrointestinal side effectsNorepinephrine reuptake inhibitorsΜ-opioid agonistMechanism of actionNeuropathic painPain conditionsReuptake inhibitorsBack painArthritic painClinical efficacyEffective medicationsClinical studiesSide effectsPainTapentadolNeuropathyOne-thirdMedicationsDiabetes
2013
The Neurobiology of Orofacial Pain
Vadivelu N, Huang Y, Mancini P, Gruenbaum S, Vadivelu A, Dabu-Bondoc S. The Neurobiology of Orofacial Pain. 2013, 1-8. DOI: 10.1007/978-3-319-01875-1_1.Peer-Reviewed Original ResearchNeuropathic orofacial painOrofacial painFacial painTemporomandibular dysfunctionCostly health issueTrigeminal neuropathic painAtypical facial painPrimary afferent nociceptorsChronic facial painComplex multifactorial etiologyOrofacial syndromesNeuropathic painAfferent nociceptorsNeurologic pathwaysUnique pathophysiologyCerebral cortexOrofacial areaMultifactorial etiologyPainClinical diagnosisHealth issuesCentral relayNumerous recent advancesFinancial burdenSexual behavior
2011
Tapentadol extended-release for treatment of chronic pain: a review
Vadivelu N, Timchenko A, Huang Y, Sinatra R. Tapentadol extended-release for treatment of chronic pain: a review. Journal Of Pain Research 2011, Volume 4: 211-218. PMID: 21887118, PMCID: PMC3160834, DOI: 10.2147/jpr.s14842.Peer-Reviewed Original ResearchLow back painNeuropathic painBack painCancer-related neuropathic painSevere chronic osteoarthritis painCentral nervous system effectsBetter gastrointestinal tolerabilityCancer-related painChronic neuropathic painDiabetic peripheral neuropathySevere acute painChronic osteoarthritis painMajor adverse eventsChronic pain conditionsNervous system effectsNorepinephrine reuptake inhibitionAnalgesic effectivenessEffective analgesiaGastrointestinal intoleranceGastrointestinal tolerabilityOsteoarthritis painAcute painAdverse eventsChronic osteoarthritisPain conditions
2008
Article Commentary: Pain after Mastectomy and Breast Reconstruction
Vadivelu N, Schreck M, Lopez J, Kodumudi G, Narayan D. Article Commentary: Pain after Mastectomy and Breast Reconstruction. The American Surgeon 2008, 74: 285-296. PMID: 18453290, DOI: 10.1177/000313480807400402.Peer-Reviewed Original ResearchConceptsSentinel node biopsyBreast cancerBreast reconstructionNode biopsyEarly treatmentInvasive therapyAcute post-operative painAcute nociceptive painPost-mastectomy painChronic neuropathic painChronic pain statesPost-operative painBreast-Conserving TherapyBreast cancer surgeryNeuropathic painPostoperative painNociceptive painOperative painPain statesCancer surgeryChronic painPhantom painPainMastectomyTherapy