DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1
Kannan K, Kaminski N, Rechavi G, Jakob-Hirsch J, Amariglio N, Givol D. DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1. Oncogene 2001, 20: 3449-3455. PMID: 11423996, DOI: 10.1038/sj.onc.1204446.Peer-Reviewed Original ResearchMeSH KeywordsApoptosisApoptotic Protease-Activating Factor 1Gene Expression ProfilingGene Expression Regulation, LeukemicGenesGenes, p53HumansLeukemia, MyeloidNeoplasm ProteinsOligonucleotide Array Sequence AnalysisProteinsRNA, MessengerRNA, NeoplasmTemperatureTranscription, GeneticTumor Cells, CulturedTumor Suppressor Protein p53ConceptsGene expression profilesGrowth arrestApaf-1Expression profilesMouse myeloid leukemic cell lineRegulated gene expression profilesP53-regulated genesDistinct transcriptional programsDNA microarray analysisCell linesTranscriptional programsCellular functionsSUMO-1Myeloid leukemic cell linesTemperature-sensitive p53MRNA speciesOligonucleotide microarraysProapoptotic genesMicroarray analysisLeukemic cell linesApoptotic processCellular responsesGenesP53 signalingStress conditions