2010
The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome
Yousem SA, Gibson K, Kaminski N, Oddis CV, Ascherman DP. The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome. Modern Pathology 2010, 23: 874-880. PMID: 20228783, DOI: 10.1038/modpathol.2010.65.Peer-Reviewed Original ResearchConceptsInterstitial lung diseaseDiffuse alveolar damageNonspecific interstitial pneumoniaUsual interstitial pneumoniaInterstitial pneumoniaSynthetase syndromeAlveolar damageNative lungPulmonary interstitial lung diseaseUsual interstitial pneumonia patternChronic interstitial lung diseaseTRNA synthetase autoantibodiesTRNA synthetase syndromeIdiopathic inflammatory myopathiesPercent of patientsSurgical lung biopsyInterstitial pneumonia patternChronic interstitial pneumoniaConnective tissue disordersAutoimmune groupInterstitial injuryAcute decompensationOrganizing pneumoniaInflammatory myopathiesLung biopsy
2009
MMP activation peptide detection in biological samples as a diagnostic marker of idiopathic pulmonary fibrosis
Voeghtly L, Kaminski N, Oury T. MMP activation peptide detection in biological samples as a diagnostic marker of idiopathic pulmonary fibrosis. The FASEB Journal 2009, 23: 572.11-572.11. DOI: 10.1096/fasebj.23.1_supplement.572.11.Peer-Reviewed Original ResearchIdiopathic pulmonary fibrosisPulmonary fibrosisAcute exacerbationMatrix metalloproteasesMMP activationChronic interstitial lung diseaseInterstitial lung diseaseUrine of miceMechanism of clearanceActivation peptideExtracellular matrix turnoverProgressive diseaseLung functionWT miceLung diseaseUnknown etiologyDisease progressionHealthy controlsHuman patientsDiagnostic markerUrine detectionFibrosisDiseaseEarly detectionMatrix turnover