Alterations in White Matter Network and Microstructural Integrity Differentiate Parkinson’s Disease Patients and Healthy Subjects
Koirala N, Anwar A, Ciolac D, Glaser M, Pintea B, Deuschl G, Muthuraman M, Groppa S. Alterations in White Matter Network and Microstructural Integrity Differentiate Parkinson’s Disease Patients and Healthy Subjects. Frontiers In Aging Neuroscience 2019, 11: 191. PMID: 31404311, PMCID: PMC6676803, DOI: 10.3389/fnagi.2019.00191.Peer-Reviewed Original ResearchPD patientsHealthy subject groupParkinson's diseaseNetwork-based statisticsDisease patientsHealthy controlsHealthy subjectsWhite matterMiddle-aged healthy controlsNetwork alterationsProbabilistic tractography analysisParkinson's disease patientsWhite matter changesSubject groupsWhite matter microstructural integrityElderly healthy controlsDistinct brain areasPD pathophysiologyWhite matter networksCorticospinal tractCorpus callosumCorona radiataMatter changesPatientsBrain areas