Mridu Gulati, MD
Associate Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine)DownloadHi-Res Photo
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Pulmonary, Critical Care & Sleep Medicine
PO Box 208057, 300 Cedar Street
New Haven, CT 06520-8057
United States
About
Titles
Associate Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine)
Biography
Dr. Mridu Gulati is board certified in Pulmonary and Critical care Medicine as well as Occupational and Environmental Medicine. Her primary areas of interest include interstitial lung disease and pulmonary occupational and environmental diseases. She is currently Associate Director of the Yale Interstitial Lung Disease Program and Director of Sarcoidosis and is a key member of its clinical and translational research program.
Appointments
Pulmonary, Critical Care & Sleep Medicine
Associate Professor on TermPrimaryOccupational & Environmental Medicine Program
Associate Professor on TermSecondary
Other Departments & Organizations
- Internal Medicine
- Interstitial Lung Disease (ILD) Program
- Occupational & Environmental Lung Diseases Program
- Occupational & Environmental Medicine Program
- Pulmonary, Critical Care & Sleep Medicine
- Scleroderma Program
- Winchester Center for Lung Disease
- Yale Medicine
- Yale Ventures
Education & Training
- Fellow
- New York University School of Medicine (2002)
- Resident
- University of Michigan Medical Center (2000)
- MD
- New York University (1997)
- BA
- Harvard University (1993)
- Fellow
- University of San Francisco School of Medicine
- Fellow
- Yale University School of Medicine
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Mridu Gulati's published research.
Publications Timeline
A big-picture view of Mridu Gulati's research output by year.
Wonnie Ryu, MD, MPH
Erica Herzog, MD, PhD
Naftali Kaminski, MD
Robert Homer, MD, PhD
Carrie A Redlich, MD, MPH, BA
Buqu Hu
81Publications
3,405Citations
Publications
2024
Long-Term Air Pollution Exposure and Severity of Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry.
Sack C, Wojdyla D, MacMurdo M, Gassett A, Kaufman J, Raghu G, Redlich C, Li P, Olson A, Leonard T, Todd J, Neely M, Snyder L, Gulati M. Long-Term Air Pollution Exposure and Severity of Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry. Annals Of The American Thoracic Society 2024 PMID: 39531618, DOI: 10.1513/annalsats.202404-382oc.Peer-Reviewed Original ResearchAltmetricConceptsAssociated with worse qualityExposure to air pollutionGene-environment interactionsQuality of lifePollution exposureEffects of long-term exposure to air pollutionLong-term exposure to PM<sub>2.5</sub> anLong-term exposure to air pollutionWorse qualityParticipant's residential addressQuality of life measuresNon-Hispanic whitesExposure to PM<sub>2.5</sub>Multi-pollutant modelsYears of follow-upCox proportional hazards modelsLower FVC %Residential addressesProportional hazards modelIPF-PRO RegistryMultivariate regression modelEffect modificationEuroQol scoresLife measuresEnrollment dateChanges in lung function and mortality risk in patients with idiopathic pulmonary fibrosis (IPF)
Oldham J, Neely M, Wojdyla D, Gulati M, Li P, Patel D, Palmer S, Todd J, Patel D. Changes in lung function and mortality risk in patients with idiopathic pulmonary fibrosis (IPF). 2024, pa674. DOI: 10.1183/13993003.congress-2024.pa674.Peer-Reviewed Original ResearchPlasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts
Sand J, Jessen H, Leeming D, Yu S, Lee C, Hu B, Sun Y, Adams T, Pivarnik T, Liu A, Woo S, McGovern J, Fiorini V, Saber T, Higuero-Sevilla J, Gulati M, Kaminski N, Damsky W, Shaw A, Mohanty S, Goobie G, Zhang Y, Herzog E, Ryu C. Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts. Thorax 2024, 79: thorax-2023-221095. PMID: 39117421, DOI: 10.1136/thorax-2023-221095.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSarcoidosis cohortMultiorgan diseasePRO-C3Interleukin-4Case Control Etiologic Study of SarcoidosisPlasma levels of interleukin-4Alpha-1 antitrypsin deficiencyLevels of interleukin-4Pathogenesis of sarcoidosisC6MC3MHealthy control patientsStudy of sarcoidosisGenomic researchAbnormal extracellular matrixAssociated with dermatological diseaseCollagen degradationScadding stageCorticosteroid useComplex diseasesPRO-C6Control patientsIL-13IL-5IL-9Innate Immune Effects of Α1-adrenoreceptor Antagonism in Sarcoidosis
Saber T, Yu S, Lee C, Fiorini V, Mcgovern J, Woo S, Gulati M, Ryu C, Herzog E. Innate Immune Effects of Α1-adrenoreceptor Antagonism in Sarcoidosis. 2024, a2531-a2531. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2531.Peer-Reviewed Original ResearchTelomere Attrition Is Associated With Sarcoidosis
Gandhi S, Lee C, Yu S, Saber T, Woo S, Mcgovern J, Fiorini V, Gulati M, Herzog E, Ryu C. Telomere Attrition Is Associated With Sarcoidosis. 2024, a2530-a2530. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2530.Peer-Reviewed Original ResearchLong-term Air Pollution Exposure Is Associated With Increased Severity of Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry
Sack C, Wojdyla D, Macmurdo M, Gassett A, Kaufman J, Raghu G, Redlich C, Li P, Olson A, Leonard T, Todd J, Neely M, Snyder L, Gulati M, on behalf of the IPF-PRO Registry investigators. Long-term Air Pollution Exposure Is Associated With Increased Severity of Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry. 2024, a1798-a1798. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a1798.Peer-Reviewed Original ResearchDevelopment and evaluation of a questionnaire to capture environmental and occupational inhalational exposures in adults with fibrotic interstitial lung disease
Swaminathan A, McFatrich M, Mkumba L, Wright L, Redlich C, Snyder L, Reeve B, Patel D, Gulati M. Development and evaluation of a questionnaire to capture environmental and occupational inhalational exposures in adults with fibrotic interstitial lung disease. Respiratory Research 2024, 25: 372. PMID: 39407223, PMCID: PMC11481565, DOI: 10.1186/s12931-024-03000-z.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsCognitive interviewsContent validityExposure questionnaireMultidisciplinary teamSemi-structured interview guideEvidence of content validityFibrosing ILDsInterstitial lung diseaseRelevant exposuresFibrotic interstitial lung diseaseClinically relevant exposuresTrained interviewersInterview guideAssessment QuestionnaireQuestionnaireInterviewsLung diseaseAdultsTeamClinicPatientsSource of misunderstandingOccupational inhalation exposureValidityDisease
2023
Circulating Mitochondrial DNA Is Associated With High Levels of Fatigue in Two Independent Sarcoidosis Cohorts
Fiorini V, Hu B, Sun Y, Yu S, McGovern J, Gandhi S, Woo S, Turcotte-Foster S, Pivarnik T, Khan Z, Adams T, Herzog E, Kaminski N, Gulati M, Ryu C. Circulating Mitochondrial DNA Is Associated With High Levels of Fatigue in Two Independent Sarcoidosis Cohorts. CHEST Journal 2023, 165: 1174-1185. PMID: 37977267, PMCID: PMC11110677, DOI: 10.1016/j.chest.2023.11.020.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPatient-related outcome measuresToll-like receptor 9Fatigue Assessment ScalePlasma mtDNA concentrationsTLR9 activationSarcoidosis patientsMtDNA concentrationsMulti-organ sarcoidosisCommon chief complaintInnate immune activationNovel therapeutic strategiesDomains of fatigueSevere clinical phenotypePsychobiologic mechanismsSarcoidosis cohortScadding stageCorticosteroid useCytokine levelsExtrapulmonary diseaseProspective cohortFAS scoresPulmonary fibrosisChief complaintImmune activationPatient populationEVALUATION OF CONTENT VALIDITY OF A NEW EXPOSURE ASSESSMENT QUESTIONNAIRE IN PATIENTS WITH FIBROSING INTERSTITIAL LUNG DISEASES
SWAMINATHAN A, MCFATRICH M, MKUMBA L, WRIGHT L, REDLICH C, SNYDER L, REEVE B, OLSON A, GULATI M. EVALUATION OF CONTENT VALIDITY OF A NEW EXPOSURE ASSESSMENT QUESTIONNAIRE IN PATIENTS WITH FIBROSING INTERSTITIAL LUNG DISEASES. CHEST Journal 2023, 164: a5103-a5104. DOI: 10.1016/j.chest.2023.07.3304.Peer-Reviewed Original ResearchProteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS‐CoV‐2 infection (PASC) syndrome
Singh I, Leitner B, Wang Y, Zhang H, Joseph P, Lutchmansingh D, Gulati M, Possick J, Damsky W, Hwa J, Heerdt P, Chun H. Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS‐CoV‐2 infection (PASC) syndrome. Pulmonary Circulation 2023, 13: e12220. PMID: 37091121, PMCID: PMC10113513, DOI: 10.1002/pul2.12220.Peer-Reviewed Original ResearchCitationsAltmetricConceptsInvasive cardiopulmonary exercise testPASC patientsPost-acute sequelaeAcute sequelaeInfection syndromeUnexplained exertional intoleranceCardiopulmonary exercise testSystemic oxygen deliveryPersistent inflammatory stateVenous blood plasmaExertional intolerancePeak exerciseEndothelial dysfunctionHemodynamic profileInflammatory stateExercise testFibrotic processPathophysiological hallmarkAberrant protein expressionExpression of proteinsOxygen deliveryOxygen extractionProteomic profilingPatientsPhysiologic responses
Clinical Trials
Current Trials
BEACON-IPF for the treatment of idiopathic pulmonary fibrosis
HIC ID2000035682RoleSub InvestigatorPrimary Completion Date12/31/2024Recruiting ParticipantsGenetic Determinants of Aneurysms in Autosomal Dominant Polycystic Kidney Disease
HIC ID2000029350RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting ParticipantsGenderBothAge18+ yearsPathogenic Wnt-beta catenin target genes in macrophages and fibrosis
HIC ID2000024862RoleSub InvestigatorPrimary Completion Date12/31/2023Recruiting Participants
Clinical Care
Overview
Clinical Specialties
Occupational Health & Environmental Medicine; Pulmonology & Sleep Medicine; Pulmonary Critical Care
Fact Sheets
Interstitial Lung Disease (ILD)
Learn More on Yale MedicineSarcoidosis
Learn More on Yale MedicineDyspnea with Advanced Cancers
Learn More on Yale MedicineAnesthesia for Organ Transplant
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Yale Medicine News
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News
- April 27, 2023
Study Uncovers Reduced Exercise Tolerance and Other Changes in Long COVID
- September 16, 2021
Discoveries & Impact (September 2021)
- May 12, 2021
Discoveries & Impact (May 2021)
- February 10, 2021
Discoveries & Impact (February 2021)
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Office Fax Number
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Mailing Address
Pulmonary, Critical Care & Sleep Medicine
PO Box 208057, 300 Cedar Street
New Haven, CT 06520-8057
United States
Locations
Lippard Laboratory of Clinical Investigation (LLCI)
Academic Office
15 York Street, Ste 101D
New Haven, CT 06510
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.