2022
Human biodistribution and radiation dosimetry of the demyelination tracer [18F]3F4AP
Brugarolas P, Wilks M, Noel J, Kaiser J, Vesper D, Ramos-Torres K, Guehl N, Macdonald-Soccorso M, Sun Y, Rice P, Yokell D, Lim R, Normandin M, El Fakhri G. Human biodistribution and radiation dosimetry of the demyelination tracer [18F]3F4AP. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 50: 344-351. PMID: 36197499, PMCID: PMC9816249, DOI: 10.1007/s00259-022-05980-w.Peer-Reviewed Original ResearchConceptsRadiation dosimetryTime-activity curvesAdverse eventsEffective doseMultiple bed positionsComprehensive metabolic panelNonhuman primatesHealthy human volunteersNo adverse eventsDynamic PET scansVoltage-gated potassiumAnimal models of neurological diseasesNonhuman primate studiesModels of neurological diseasesHuman biodistributionAverage effective doseMetabolic panelDosimetryOLINDA softwareHealthy volunteersUrinary bladderPET scansDemyelinating lesionsBed positionAnimal models
2013
Factors affecting tumor 18 F-FDG uptake in longitudinal mouse PET studies
Sha W, Ye H, Iwamoto K, Wong K, Wilks M, Stout D, McBride W, Huang S. Factors affecting tumor 18 F-FDG uptake in longitudinal mouse PET studies. EJNMMI Research 2013, 3: 51. PMID: 23841937, PMCID: PMC3718724, DOI: 10.1186/2191-219x-3-51.Peer-Reviewed Original ResearchF-FDG uptakeF-FDG positron emission tomographyF-FDGMDA-MB-231Positron emission tomographyEffect of blood glucose levelsTumor diameterBlood glucose levelsF-FDG PET scansSevere combined immunodeficient miceGlucose levelsTumor-bearing micePositron emission tomography imagingMultivariate regression analysisHeart time-activity curveTime-activity curvesTumor sizeImmunodeficient miceTumor-dependentTumor typesPET scansTumor growthPlasma curveTumorPatlak analysis