2024
Long-term surveillance of invasive pneumococcal disease: The impact of 10-valent pneumococcal conjugate vaccine in the metropolitan region of Salvador, Brazil
Reis J, Azevedo J, de Oliveira A, de Oliveira Menezes A, Pedrosa M, dos Santos M, Ribeiro L, de Freitas H, Gouveia E, Teles M, da Glória Carvalho M, Reis M, Nascimento-Carvalho C, Verani J. Long-term surveillance of invasive pneumococcal disease: The impact of 10-valent pneumococcal conjugate vaccine in the metropolitan region of Salvador, Brazil. Vaccine 2024, 42: 591-597. PMID: 38184393, PMCID: PMC10872423, DOI: 10.1016/j.vaccine.2023.12.055.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInvasive pneumococcal diseaseLower-middle-income settingsPCV10 introductionInvasive pneumococcal disease incidenceProspective laboratory-based surveillanceNational infant immunization programsPre-PCV10 periodNon-vaccine serotypesRate ratiosInfant immunization programIncidence ratePneumococcal conjugate vaccineLaboratory-based surveillanceIPD incidenceImpact of PCV10Multiplex polymerase chain reactionMetropolitan region of SalvadorCompare ratesPCV10 serotypesLong-term impactSterile sitesQuellung reactionSerotype 15BVaccine-type
2022
Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distribution
2021
Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil
Silva M, Kikuti M, Anjos R, Portilho M, Santos V, Gonçalves T, Tauro L, Moreira P, Jacob-Nascimento L, Santana P, Campos G, Siqueira A, Kitron U, Reis M, Ribeiro G. Risk of chronic arthralgia and impact of pain on daily activities in a cohort of patients with chikungunya virus infection from Brazil. International Journal Of Infectious Diseases 2021, 105: 608-616. PMID: 33684559, DOI: 10.1016/j.ijid.2021.03.003.Peer-Reviewed Original ResearchConceptsChronic arthralgiaChikungunya virus infectionRisk factorsVirus infectionDaily activitiesAcute febrile illnessIndependent risk factorPersistence of painCohort of patientsImpact of painProgression of diseaseTranscriptase-polymerase chain reactionPersistent arthralgiaFebrile illnessSubstantial disabilityViral loadFemale sexPolymerase chain reactionIgM enzymeArthralgiaSurveillance studyChikungunya virusDengue virusPatientsImmunosorbent assay
2020
Influence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil - Volume 26, Number 2—February 2020 - Emerging Infectious Diseases journal - CDC
Hacker KP, Sacramento GA, Cruz JS, de Oliveira D, Nery N, Lindow JC, Carvalho M, Hagan J, Diggle PJ, Begon M, Reis MG, Wunder EA, Ko AI, Costa F. Influence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil - Volume 26, Number 2—February 2020 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2020, 26: 311-314. PMID: 31961288, PMCID: PMC6986844, DOI: 10.3201/eid2602.190102.Peer-Reviewed Original Research
2019
Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features
Leal H, Azevedo J, Silva G, Amorim A, de Roma L, Arraes A, Gouveia E, Reis M, Mendes A, de Oliveira Silva M, Barberino M, Martins I, Reis J. Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features. BMC Infectious Diseases 2019, 19: 609. PMID: 31296179, PMCID: PMC6624930, DOI: 10.1186/s12879-019-4265-z.Peer-Reviewed Original ResearchConceptsK. pneumoniaePrevious antimicrobial useLaboratory-based surveillanceAntimicrobial susceptibility testingMDR bacteremiaMDR-GNBDrug-resistant pathogensNegative bacteremiaLiver diseaseBloodstream infectionsHigh morbidityMale sexRisk factorsEpidemiological aspectsNegative bacilliHealthcare professionalsMicrobiological featuresSusceptibility testingBacteremiaInfectionAntimicrobial useCausative agentAntibiotic resistanceIntervention measuresResistance determinantsAccuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue
Kikuti M, Cruz J, Rodrigues M, Tavares A, Paploski I, Silva M, Santana P, Tauro L, Silva G, Campos G, Araújo J, Kitron U, Reis M, Ribeiro G. Accuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue. PLOS ONE 2019, 14: e0213301. PMID: 30840708, PMCID: PMC6402663, DOI: 10.1371/journal.pone.0213301.Peer-Reviewed Original ResearchConceptsRapid diagnosis testsNon-dengue febrile patientsFebrile patientsHealthy controlsBlood donorsLaboratory-confirmed dengue casesSD BIOLINE Dengue DuoSecondary DENV infectionDengue virus antigenAcute-phase seraDengue diagnostic testsRepresentative serum samplesDengue-endemic regionsDengue-endemic areasSample of casesDENV antibodiesDENV infectionNS1 ELISAPrimary infectionDengue diagnosisMedical treatment decisionsTreatment decisionsVirus antigenRDT accuracyRDT sensitivity
2016
Genetic profiles and antimicrobial resistance of Streptococcus pneumoniae non-PCV10 serotype isolates recovered from meningitis cases in Salvador, Brazil
Azevedo J, Dos Anjos ES, Cordeiro S, Dos Santos M, Escobar E, Lobo P, Carvalho MD, Reis M, Reis J, Campos L. Genetic profiles and antimicrobial resistance of Streptococcus pneumoniae non-PCV10 serotype isolates recovered from meningitis cases in Salvador, Brazil. Journal Of Medical Microbiology 2016, 65: 1164-1170. PMID: 27599851, DOI: 10.1099/jmm.0.000346.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBrazilChildChild, PreschoolDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleGenetic VariationGenotypeHospitalsHumansInfantMaleMeningitis, PneumococcalMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingMultiplex Polymerase Chain ReactionPneumococcal VaccinesSerogroupSerotypingStreptococcus pneumoniaeYoung AdultConceptsPost-vaccine periodMulti-locus sequence typing resultsIntroduction of PCV10Non-vaccine serotypesCases of meningitisPneumococcal conjugate vaccineBenefits of vaccinationChildhood vaccination programsAntimicrobial susceptibility testingMulti-locus sequence typingPCV10 introductionPneumococcal meningitisConjugate vaccineReference hospitalSerotype 19AMeningitis casesSerotype 12FVaccination programMore antibioticsSerotype isolatesQuellung reactionE-testStreptococcus pneumoniaeMeningitisSusceptibility testing
2013
Longitudinal surveillance for meningitis by Acinetobacter in a large urban setting in Brazil
Coelho-Souza T, Reis J, Martins N, Martins I, Menezes A, Reis M, Silva N, Dias R, Riley L, Moreira B. Longitudinal surveillance for meningitis by Acinetobacter in a large urban setting in Brazil. Clinical Microbiology And Infection 2013, 19: e241-e244. PMID: 23398654, PMCID: PMC3625502, DOI: 10.1111/1469-0691.12145.Peer-Reviewed Original ResearchMeSH KeywordsAcinetobacter baumanniiAcinetobacter InfectionsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBrazilCarbapenemsChildChild, PreschoolColistinDrug Resistance, Multiple, BacterialEpidemiological MonitoringFemaleHumansMaleMeningitis, BacterialMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingUrban PopulationYoung AdultConceptsMultilocus sequence typingA. baumanniiCarbapenem resistanceClonal complexesDissemination of infectionLongitudinal surveillanceAcinetobacter baumanniiLarge urban settingMeningitisStudy aimBaumanniiSequence typingUrban settingsAntimicrobial agentsSurveillance systemSurveillanceColistinInfectionSetting
2011
TNF-alpha and IL-8: Serum levels and gene polymorphisms (−308G>A and −251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia
Cajado C, Cerqueira B, Couto F, Moura-Neto J, Vilas-Boas W, Dorea M, Lyra I, Barbosa C, Reis M, Goncalves M. TNF-alpha and IL-8: Serum levels and gene polymorphisms (−308G>A and −251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia. Cytokine 2011, 56: 312-317. PMID: 21802960, DOI: 10.1016/j.cyto.2011.07.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAllelesAnemia, Sickle CellBiomarkersCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayHaplotypesHumansInterleukin-8Medical History TakingPolymerase Chain ReactionPolymorphism, GeneticPolymorphism, Restriction Fragment LengthTumor Necrosis Factor-alphaConceptsSickle cell anemiaTNF-alpha -308GT gene polymorphismGene polymorphismsIL-8Serum levelsMedical historyTNF-alphaCell anemiaHigher TNF-alpha levelsIL-8 gene polymorphismsA alleleClassical biomarkersSteady-state sickle cell anemiaTNF-alpha levelsHeterogeneous clinical outcomesLogistic regression analysisYears of ageCytokine levelsClinical outcomesImmunological biomarkersHealthy controlsPatient outcomesInterleukin-8SCA patients
2010
Promoter region sequence differences in the A and G gamma globin genes of Brazilian sickle cell anemia patients
Barbosa C, Goncalves-Santos N, Souza-Ribeiro S, Moura-Neto J, Takahashi D, Silva D, Hurtado-Guerrero A, Reis M, Goncalves M. Promoter region sequence differences in the A and G gamma globin genes of Brazilian sickle cell anemia patients. Brazilian Journal Of Medical And Biological Research 2010, 43: 705-711. PMID: 20602015, DOI: 10.1590/s0100-879x2010007500062.Peer-Reviewed Original Research
2009
Risk factors for failure to complete a course of latent tuberculosis infection treatment in Salvador, Brazil.
Machado A, Finkmoore B, Emodi K, Takenami I, Barbosa T, Tavares M, Reis M, Arruda S, Riley L. Risk factors for failure to complete a course of latent tuberculosis infection treatment in Salvador, Brazil. The International Journal Of Tuberculosis And Lung Disease 2009, 13: 719-25. PMID: 19460247.Peer-Reviewed Original ResearchConceptsHousehold contactsLatent tuberculosis infectionLTBI treatmentLatent tuberculosis infection treatmentTB-endemic countriesRisks of treatmentHigh-risk populationPulmonary TBMedication intoleranceTuberculosis infectionTuberculosis controlRisk factorsHigh riskSide effectsInfection treatmentHospitalVisitsMonthsTreatmentFollowINHRiskTBRegimenPatientsAnalysis of discordance between the tuberculin skin test and the interferon-gamma release assay.
Machado A, Emodi K, Takenami I, Finkmoore B, Barbosa T, Carvalho J, Cavalcanti L, Santos G, Tavares M, Mota M, Barreto F, Reis M, Arruda S, Riley L. Analysis of discordance between the tuberculin skin test and the interferon-gamma release assay. The International Journal Of Tuberculosis And Lung Disease 2009, 13: 446-53. PMID: 19335949.Peer-Reviewed Original ResearchConceptsTuberculin skin testInterferon-gamma releaseHousehold contactsSkin testTST resultsLatent TB infectionPositive TST resultsPulmonary tuberculosis patientsChest X-rayAnalysis of discordancePTB patientsTB infectionTuberculosis patientsLung scarsIndex caseTest groupTest agreementPatientsIGRAPositive resultsGroupDiscordanceInfectionRelease
2008
Sequence change in the HS2-LCR and Gg-globin gene promoter region of sickle cell anemia patients
Adorno E, Moura-Neto J, Lyra I, Zanette A, Santos L, Seixas M, Reis M, Goncalves M. Sequence change in the HS2-LCR and Gg-globin gene promoter region of sickle cell anemia patients. Brazilian Journal Of Medical And Biological Research 2008, 41: 95-98. PMID: 18235968, DOI: 10.1590/s0100-879x2008005000002.Peer-Reviewed Original Research
2004
Childhood stunting in Northeast Brazil: the role of Schistosoma mansoni infection and inadequate dietary intake
Assis A, Prado M, Barreto M, Reis M, Conceição Pinheiro S, Parraga I, Blanton R. Childhood stunting in Northeast Brazil: the role of Schistosoma mansoni infection and inadequate dietary intake. European Journal Of Clinical Nutrition 2004, 58: 1022-1029. PMID: 15220944, DOI: 10.1038/sj.ejcn.1601926.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnimalsBody HeightBrazilChildChild DevelopmentChild Nutritional Physiological PhenomenaCross-Sectional StudiesDietDietary CarbohydratesDietary FatsDietary ProteinsEnergy IntakeFecesFemaleGrowth DisordersHumansIntestinal Diseases, ParasiticLogistic ModelsMaleSchistosomiasis mansoniConceptsSchistosoma mansoni infectionS. mansoni infectionInadequate dietary intakeMansoni infectionDietary intakeS. mansoniHeavy S. mansoni infectionS. mansoni endemic areasDevelopment of stuntingRisk of stuntingCross-sectional studyUninfected childrenNutritional interventionDietary measuresInadequate intakeCarbohydrate intakeStool samplesHigh riskMedian proteinEndemic areasParasitic infectionsCaloric consumptionChildhood stuntingAge groupsAdequate diet
2002
Epidemiology of schoolchildren's cognitive development in Jequié, Bahia State, Brazil: assessment procedures and general results.
Santos D, Borges A, Pereira P, Chalhub A, Happe F, Silva R, Assis A, Blanton R, Parraga I, Reis M, Almeida Filho N, Barreto M. Epidemiology of schoolchildren's cognitive development in Jequié, Bahia State, Brazil: assessment procedures and general results. Cadernos De Saúde Pública 2002, 18: 723-33. PMID: 12048598.Peer-Reviewed Original ResearchConceptsSchool gradesCognitive developmentMean scoreTeacher profilesSchool resourcesSchool achievementGrade girlsTest scoresRaven testRaven's Progressive MatricesRaven scoresAssessment proceduresGradeProgressive MatricesTeachersGirlsStudentsUrban communitiesAchievementSchoolchildrenScienceQuestionnaireScoresDevelopmentChildren
2001
Referral pattern of leptospirosis cases during a large urban epidemic of dengue.
Flannery B, Pereira MM, Velloso L de F, Carvalho C de C, De Codes LG, Orrico G de S, Dourado CM, Riley LW, Reis MG, Ko AI. Referral pattern of leptospirosis cases during a large urban epidemic of dengue. American Journal Of Tropical Medicine And Hygiene 2001, 65: 657-63. PMID: 11716133, DOI: 10.4269/ajtmh.2001.65.657.Peer-Reviewed Original ResearchConceptsInfectious diseases reference hospitalFirst medical evaluationLarge urban epidemicDays of illnessInfectious Diseases HospitalIntensive care unitOnset of illnessCases of leptospirosisDiagnosis of dengueDiseases HospitalCare unitInitial diagnosisReference hospitalReferral patternsAmbulatory clinicsLeptospirosis epidemicMedical evaluationConcurrent epidemicsDengue diagnosisDiagnostic confusionUrban epidemicEarly symptomsHigh mortalityLeptospirosis casesLeptospirosis
2000
Lower Hookworm Incidence, Prevalence, and Intensity of Infection in Children with a Bacillus Calmette-Guérin Vaccination Scar
Barreto M, Rodrigues L, Silva R, Assis A, Reis M, Santos C, Blanton R. Lower Hookworm Incidence, Prevalence, and Intensity of Infection in Children with a Bacillus Calmette-Guérin Vaccination Scar. The Journal Of Infectious Diseases 2000, 182: 1800-1803. PMID: 11069259, DOI: 10.1086/317627.Peer-Reviewed Original ResearchConceptsBCG vaccination scarBacillus Calmette-GuérinVaccination scarIntensity of infectionBacillus Calmette-Guérin (BCG) vaccination scarHuman immunodeficiency virus-infected adultsHuman immunological responsesOngoing prospective studyVaccination protectionIncidence ratiosProspective studyAdjusted prevalenceHookworm infectionCalmette-GuérinTrichuris trichiuraImmunological responseCommon vaccinesImmune systemHookworm prevalenceDifferent helminthsLogistic regressionPrevalenceSchistosoma mansoniIncidenceInfectionClonally Related Penicillin-Nonsusceptible Streptococcus pneumoniae Serotype 14 from Cases of Meningitis in Salvador, Brazil
Ko A, Reis J, Coppola S, Gouveia E, Cordeiro S, Lôbo T, Pinheiro R, Salgado K, Dourado C, Tavares-Neto J, Rocha H, Reis M, Johnson W, Riley L. Clonally Related Penicillin-Nonsusceptible Streptococcus pneumoniae Serotype 14 from Cases of Meningitis in Salvador, Brazil. Clinical Infectious Diseases 2000, 30: 78-86. PMID: 10619737, DOI: 10.1086/313619.Peer-Reviewed Original ResearchConceptsPenicillin-nonsusceptible isolatesSerotype 14 isolatesSerotype 14Pneumococcal meningitisActive hospital-based surveillanceCases of meningitisHospital-based surveillancePrevious antibiotic useIntermediate-level resistanceSerotype 14 strainsPolymerase chain reaction analysisAntibiotic useChain reaction analysisPrevalent serotypesMeningitisUnrelated patternsPCR patternsCity of SalvadorPatientsStreptococcus pneumoniae serotype 14Reaction analysisIsolatesLarge proportionGeographic areasInfection
1998
Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil 1 2 3
Assis A, Barreto M, Prado M, Reis M, Parraga I, Blanton R. Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil 1 2 3. American Journal Of Clinical Nutrition 1998, 68: 1247-1253. PMID: 9846854, DOI: 10.1093/ajcn/68.6.1247.Peer-Reviewed Original ResearchConceptsBody mass indexNutritional statusMidarm circumferenceMansoni infectionMass indexSchistosome infectionChronic S. mansoni infectionDouble-blind trialDouble-blind fashionSchistosoma mansoni infectionS. mansoni infectionTriceps skinfold thicknessArm muscle areaPlacebo groupBrazilian schoolchildrenAnthropometric measurementsAnthropometric measuresSkinfold thicknessRate of improvementUntreated boysInfectionMuscle areaSignificant differencesSignificant increaseShort-term growth
1996
Gender differences in growth of school-aged children with schistosomiasis and geohelminth infection.
Parraga I, Assis A, Prado M, Barreto M, Reis M, King C, Blanton R. Gender differences in growth of school-aged children with schistosomiasis and geohelminth infection. American Journal Of Tropical Medicine And Hygiene 1996, 55: 150-6. PMID: 8780452, DOI: 10.4269/ajtmh.1996.55.150.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnalysis of VarianceAnthropometryAscariasisBody CompositionBrazilCase-Control StudiesChildDouble-Blind MethodFecesFemaleGrowth DisordersHumansMaleNutrition DisordersNutritional StatusParasite Egg CountProspective StudiesSchistosomiasis mansoniSex CharacteristicsSocioeconomic FactorsTrichuriasisConceptsUpper arm circumferenceTriceps skinfoldS. mansoniS. mansoni-infected childrenMid-upper arm circumferenceModerate-intensity infectionDevelopment of malnutritionEffect of treatmentSubscapular skinfold measurementsInfected boysInfected childrenArm circumferenceGeohelminth infectionsSchool-aged childrenIntensity of infectionBrazilian schoolchildrenAnthropometric measurementsChronic malnutritionIntensity infectionsControl childrenGrowth retardationGrowth deficitsSchistosoma mansoniSkinfold measurementsInfection