2023
Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study
Barbosa L, Santiago M, Moretto V, Athanazio D, Takahashi D, Reis E, Lopes M, Lemaire D, Reis M. Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study. Brazilian Journal Of Biology 2023, 83: e244123. PMID: 34161457, DOI: 10.1590/1519-6984.244123.Peer-Reviewed Original ResearchMeSH KeywordsBrazilGene FrequencyGenetic Predisposition to DiseaseHumansLupus Erythematosus, SystemicPilot ProjectsToll-Like Receptor 9ConceptsSystemic lupus erythematosusToll-like receptor 9TLR9 polymorphismsSLE patientsLupus erythematosusSingle nucleotide polymorphismsToll-like receptor 9 polymorphismsControl groupTLR9 single nucleotide polymorphismsSLE patient groupInnate immune systemDiscoid rashSLE populationClinical manifestationsPatient groupAutoimmune diseasesReceptor 9Brazilian patientsTLR9 geneImmune systemPatientsPilot studyAllele GAllele CGenotype frequencies
2010
Evaluating glutathione S‐Transferase (GST) null genotypes (GSTT1 and GSTM1) as a potential biomarker of predisposition for developing leukopenia
GONCALVES M, NETO J, SOUZA C, MELO P, REIS M. Evaluating glutathione S‐Transferase (GST) null genotypes (GSTT1 and GSTM1) as a potential biomarker of predisposition for developing leukopenia. International Journal Of Laboratory Hematology 2010, 32: e49-e56. PMID: 19555437, DOI: 10.1111/j.1751-553x.2009.01169.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBrazilFemaleGene DeletionGenetic Predisposition to DiseaseGenotypeGlutathione TransferaseHumansLeukopeniaMaleConceptsGSTM1 null genotypeNull genotypeBiomarkers of susceptibilityWhite blood cell countGlutathione S-transferase null genotypeOccurrence of leukopeniaRisk of neutropeniaBlood cell countCase-control studyWhite blood cell deficiencyGlutathione S-transferaseGSTT1 null genotypeOxidative stress productsBlood cell deficiencyGSTM1 genotypeLeukopeniaNormal subjectsCell countPotential biomarkersNeutropeniaGSTT1BiomarkersStress productsRiskSubjects