2024
Long-term surveillance of invasive pneumococcal disease: The impact of 10-valent pneumococcal conjugate vaccine in the metropolitan region of Salvador, Brazil
Reis J, Azevedo J, de Oliveira A, de Oliveira Menezes A, Pedrosa M, dos Santos M, Ribeiro L, de Freitas H, Gouveia E, Teles M, da Glória Carvalho M, Reis M, Nascimento-Carvalho C, Verani J. Long-term surveillance of invasive pneumococcal disease: The impact of 10-valent pneumococcal conjugate vaccine in the metropolitan region of Salvador, Brazil. Vaccine 2024, 42: 591-597. PMID: 38184393, PMCID: PMC10872423, DOI: 10.1016/j.vaccine.2023.12.055.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInvasive pneumococcal diseaseLower-middle-income settingsPCV10 introductionInvasive pneumococcal disease incidenceProspective laboratory-based surveillanceNational infant immunization programsPre-PCV10 periodNon-vaccine serotypesRate ratiosInfant immunization programIncidence ratePneumococcal conjugate vaccineLaboratory-based surveillanceIPD incidenceImpact of PCV10Multiplex polymerase chain reactionMetropolitan region of SalvadorCompare ratesPCV10 serotypesLong-term impactSterile sitesQuellung reactionSerotype 15BVaccine-type
2023
Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community
Anjos R, Portilho M, Jacob-Nascimento L, Carvalho C, Moreira P, Sacramento G, Nery N, de Oliveira D, Cruz J, Cardoso C, Argibay H, Plante K, Plante J, Weaver S, Kitron U, Reis M, Ko A, Costa F, Ribeiro G. Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community. PLOS Neglected Tropical Diseases 2023, 17: e0011863. PMID: 38150470, PMCID: PMC10775974, DOI: 10.1371/journal.pntd.0011863.Peer-Reviewed Original ResearchThe impact of COVID-19 on microbiological profile and antibiotic consumption in ICU: a retrospective study in an infectious disease hospital in Brazil
de França Diniz Rocha V, da Silva E, Azevedo J, Ribeiro M, Reis M, Barros T, Reis J. The impact of COVID-19 on microbiological profile and antibiotic consumption in ICU: a retrospective study in an infectious disease hospital in Brazil. The Brazilian Journal Of Infectious Diseases 2023, 28: 103705. PMID: 38065221, PMCID: PMC10764251, DOI: 10.1016/j.bjid.2023.103705.Peer-Reviewed Original ResearchConceptsIntensive care unitInfectious Diseases HospitalAntimicrobial resistanceMicrobiological profileCandida sppRetrospective studyTracheal secretionsCarbapenem-resistant A. baumanniiConsequences of antimicrobial resistanceIntensive care unit patient-daysImpact of antimicrobial resistanceMultidrug-resistant Enterococcus faeciumCharacteristics of patientsConsumption of ceftriaxoneConsumption of antibioticsPiperacillin-tazobactamUnique characteristics of patientsA. baumanniiAcinetobacter baumanniiAntibiotic consumptionEnterobacter speciesIncidence densityESKAPE groupClinical culturesKlebsiella pneumoniaeAnalyses of Early ZIKV Genomes Are Consistent with Viral Spread from Northeast Brazil to the Americas
de Moraes L, Portilho M, Vrancken B, Van den Broeck F, Santos L, Cucco M, Tauro L, Kikuti M, Silva M, Campos G, Reis M, Barral A, Barral-Netto M, Boaventura V, Vandamme A, Theys K, Lemey P, Ribeiro G, Khouri R. Analyses of Early ZIKV Genomes Are Consistent with Viral Spread from Northeast Brazil to the Americas. Viruses 2023, 15: 1236. PMID: 37376536, PMCID: PMC10301521, DOI: 10.3390/v15061236.Peer-Reviewed Original ResearchConceptsAcute ZIKV infectionSpread of ZIKVPublic health responseZika virus outbreakClinical symptomsZIKV infectionHealth responseZIKVZIKV genomeViral spreadGenomic surveillanceVirus outbreakInfectionSubsequent disseminationSurveillance effortsZIKV dynamicsFuture surveillance effortsOutbreakEarly stagesZika virus RNA persistence and recovery in water and wastewater: An approach for Zika virus surveillance in resource-constrained settings
Zhu K, Hill C, Muirhead A, Basu M, Brown J, Brinton M, Hayat M, Venegas-Vargas C, Reis M, Casanovas-Massana A, Meschke J, Ko A, Costa F, Stauber C. Zika virus RNA persistence and recovery in water and wastewater: An approach for Zika virus surveillance in resource-constrained settings. Water Research 2023, 241: 120116. PMID: 37270953, PMCID: PMC10330535, DOI: 10.1016/j.watres.2023.120116.Peer-Reviewed Original ResearchConceptsZIKV RNAZIKV outbreakZika virus surveillanceNucleic acid testingZika virus epidemicResource-constrained settingsWidespread diagnostic testingPublic health surveillanceReverse transcription droplet digital PCRTranscription droplet digital PCRAcid testingRNA persistenceDiagnostic testingHealth surveillanceDroplet digital PCRVirus epidemicVirus surveillanceIndividual testingSuch casesDigital PCRSurveillanceOutbreakRNAZIKVRecoveryMalaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil
Rocha V, Brasil L, Gomes E, Khouri R, Ferreira G, Vasconcelos B, Gouveia M, Santos T, Reis M, Lacerda M. Malaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0598-2022. PMID: 37222351, PMCID: PMC10204151, DOI: 10.1590/0037-8682-0598-2022.Peer-Reviewed Original ResearchConceptsCOVID-19 coinfectionSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Severe vivax malariaIntensive care unitSyndrome coronavirus 2Coronavirus disease 2019Transcription-quantitative PCR resultsSevere malariaCare unitCoronavirus 2Vivax malariaDifferential diagnosisDisease 2019Febrile diseaseEndemic areasPlasmodium vivaxEndemic regionsCoinfectionRapid testMalariaPCR resultsQuantitative PCRHypotensionBartonella in Norway rats (Rattus norvegicus) from the urban slum environment in Brazil
Zeppelini C, Oliveira D, Kosoy M, Reis M, Ko A, Childs J, Costa F. Bartonella in Norway rats (Rattus norvegicus) from the urban slum environment in Brazil. Anais Da Academia Brasileira De Ciências 2023, 95: e20220809. PMID: 37909607, DOI: 10.1590/0001-3765202320220809.Peer-Reviewed Original ResearchEpidemiological indicators of Chagas disease in the metropolitan region of Salvador, Bahia, Brazil
Lanza F, Ribeiro-Jr G, Miranda D, Santos F, Carvalho C, Cunha G, Carneiro I, Reis R, Cunha J, Cardoso C, Soares J, Araújo F, Reis M. Epidemiological indicators of Chagas disease in the metropolitan region of Salvador, Bahia, Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0185-2022. PMID: 36820652, PMCID: PMC9957123, DOI: 10.1590/0037-8682-0185-2022.Peer-Reviewed Original ResearchAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study
Pieri O, Bezerra F, Coelho P, Enk M, Favre T, Graeff-Teixeira C, Oliveira R, Reis M, Andrade L, Beck L, Favero V, Fialho T, Guimarães R, Oliveira B, Pascoal V, Pinheiro M, Santos R, Silva L, Siqueira I, Souza R, Katz N. Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0238-2022. PMID: 36700600, PMCID: PMC9870275, DOI: 10.1590/0037-8682-0238-2022.Peer-Reviewed Original ResearchConceptsCathodic antigenKato-KatzUrine-based pointSchistosomiasis mansoni infectionDifferent prevalence estimatesCare diagnostic testsSchistosomiasis elimination programmesWorld Health OrganizationMansoni infectionMulticenter studyStool samplesUrine pointPrevalence estimatesS. mansoniElimination programInfection statusDiagnostic testsHealth OrganizationUrine samplesHelmintexAntigenInfectionPrevalenceMansoniCareToll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study
Barbosa L, Santiago M, Moretto V, Athanazio D, Takahashi D, Reis E, Lopes M, Lemaire D, Reis M. Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study. Brazilian Journal Of Biology 2023, 83: e244123. PMID: 34161457, DOI: 10.1590/1519-6984.244123.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusToll-like receptor 9TLR9 polymorphismsSLE patientsLupus erythematosusSingle nucleotide polymorphismsToll-like receptor 9 polymorphismsControl groupTLR9 single nucleotide polymorphismsSLE patient groupInnate immune systemDiscoid rashSLE populationClinical manifestationsPatient groupAutoimmune diseasesReceptor 9Brazilian patientsTLR9 geneImmune systemPatientsPilot studyAllele GAllele CGenotype frequencies
2022
Rickettsial Infections Causing Acute Febrile Illness in Urban Slums, Brazil - Volume 28, Number 10—October 2022 - Emerging Infectious Diseases journal - CDC
Fournier JB, Blanton LS, Nery N, Wunder EA, Costa F, Reis MG, Ribeiro GS, Walker DH, Ko AI. Rickettsial Infections Causing Acute Febrile Illness in Urban Slums, Brazil - Volume 28, Number 10—October 2022 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2022, 28: 2132-2134. PMID: 36148970, PMCID: PMC9514363, DOI: 10.3201/eid2810.220497.Peer-Reviewed Original ResearchLinking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil
Eyre MT, Souza FN, Carvalho-Pereira T, Nery N, de Oliveira D, Cruz JS, Sacramento GA, Khalil H, Wunder EA, Hacker KP, Hagan JE, Childs JE, Reis MG, Begon M, Diggle PJ, Ko AI, Giorgi E, Costa F. Linking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil. ELife 2022, 11: e73120. PMID: 36111781, PMCID: PMC9560157, DOI: 10.7554/elife.73120.Peer-Reviewed Original ResearchConceptsInfection riskSignificant global public health burdenCommunity-based cohort studyGlobal public health burdenPublic health burdenAgents of leptospirosisExposure of interestYears of agePublic health interventionsHigh-risk communitiesJoint spatial modellingZoonotic spilloverCohort studyHuman infection riskMale genderSerological evidenceHealth burdenLeptospira infectionLeptospiral infectionInfection rateHealth interventionsEco-epidemiological studiesHealth surveillanceFundação de Amparo à PesquisaOswaldo Cruz FoundationEvidence for local transmission and maintenance of schistosomiasis in an urban neighbourhood in Northeast Brazil
Chaves C, Sabino‐Santos G, Cedraz F, Santos‐Muccillo P, Filho J, Zanardi V, Moretto V, Santos A, Simões F, Barbosa L, Silva L, Reis M, Blanton R. Evidence for local transmission and maintenance of schistosomiasis in an urban neighbourhood in Northeast Brazil. Transboundary And Emerging Diseases 2022, 69: 3153-3159. PMID: 36057790, PMCID: PMC11013574, DOI: 10.1111/tbed.14692.Peer-Reviewed Original ResearchConceptsLocal transmissionSchistosoma mansoni infectionRural-urban migrationImportant demographic shiftPatterns of urbanizationUrban schistosomiasisMansoni infectionEpidemiological dataUrban neighborhoodsDemographic shiftsSchistosomiasisLocal transmission cyclesRural areasTransmission cycleUrban populationMetropolitan areaSame cityNeighborhoodUrbanizationStructural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distributionEvaluation of the impact of chemical control on the ecology of Rattus norvegicus of an urban community in Salvador, Brazil
Pertile A, Lustosa R, Carvalho-Pereira T, Pedra G, Panti-May J, Oliveira U, Zeppelini C, Souza F, Oliveira D, Khalil H, Reis M, Childs J, Ko A, Begon M, Costa F. Evaluation of the impact of chemical control on the ecology of Rattus norvegicus of an urban community in Salvador, Brazil. PLOS ONE 2022, 17: e0270568. PMID: 35857771, PMCID: PMC9299319, DOI: 10.1371/journal.pone.0270568.Peer-Reviewed Original ResearchConceptsRodent control programsDemographic variablesSpirochete Leptospira interrogansControl interventionsCommunity settingsR. norvegicusChi-squareControl of zoonosesLeptospira interrogansChemical interventionDemographic characteristicsInterventionIntervention campaignsRodentsSynanthropic rodentsMonthsBody massControl programsControl practicesRattus norvegicusControl campaignsUrban poor communitiesPopulationEnvironmental transmissionAnalysis of varianceUnequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil
Aromolaran A, Araujo K, Ladines-Lim JB, Nery N, do Rosário MS, Rastely VN, Archanjo G, Daltro D, da Silveira Carvalho G, Pimentel K, de Almeida JRM, de Siqueira IC, Ribeiro HC, Oliveira-Filho J, de Oliveira D, Henriques DF, Rodrigues SG, da Costa Vasconcelos P, de Almeida ARP, Sacramento GA, Cruz JS, Sarno M, de Paula Freitas B, Mattos A, Khouri R, Reis MG, Ko AI, Costa F. Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil. International Journal Of Infectious Diseases 2022, 120: 201-204. PMID: 35470025, PMCID: PMC9119857, DOI: 10.1016/j.ijid.2022.04.030.Peer-Reviewed Original ResearchConceptsZIKV exposurePregnant womenSocioeconomic statusRelative disease burdenCongenital Zika syndromeZika virus epidemicLow socioeconomic statusZika syndromeClinical presentationDisease burdenSimilar prevalenceSerologic dataDifferent socioeconomic statusS HospitalHospitalLarge hospitalsMicrocephalyStudy centersVirus epidemicWomenPositive associationInfantsUnequal burdenHigh rateExposure rateDiversity of Mosquitoes (Diptera: Culicidae) in an Atlantic Forest Urban Park, Salvador, Brazil
de Souza R, dos Santos Ferreira G, Borja L, de Jesus Nazaré R, Mugabe V, Argibay H, Portilho M, Jacob-Nascimento L, Reis M, Kitron U, Ribeiro G. Diversity of Mosquitoes (Diptera: Culicidae) in an Atlantic Forest Urban Park, Salvador, Brazil. Journal Of Medical Entomology 2022, 59: 1065-1070. PMID: 35244168, DOI: 10.1093/jme/tjac007.Peer-Reviewed Original ResearchCOVID-19 vaccine hesitancy and associated factors according to sex: A population-based survey in Salvador, Brazil
Nery N, Ticona J, Cardoso C, Prates A, Vieira H, de Almeida A, da Silva Souza M, dos Reis O, Pellizzaro M, Portilho M, da Anunciação R, Victoriano R, dos Anjos R, Argibay H, Lima D, Mesquita I, Conceição W, Santana P, Oliveira E, Santana P, Brodskyn C, Fraga D, da Silva Solcà M, Reis M, Costa F, Ribeiro G. COVID-19 vaccine hesitancy and associated factors according to sex: A population-based survey in Salvador, Brazil. PLOS ONE 2022, 17: e0262649. PMID: 35061811, PMCID: PMC8782400, DOI: 10.1371/journal.pone.0262649.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccine hesitancyVaccine hesitancyCOVID-19 vaccineCOVID-19 riskCOVID-19 vaccine acceptanceInfluenza vaccination historyPopulation-based surveyCoronavirus disease 2019Less vaccine hesitancyHigher educational levelInfluenza vaccinationVaccination historyMultivariable analysisPrevious diagnosisVaccine acceptanceAssociated FactorsVaccine campaignDisease 2019VaccineComorbiditiesHesitancyCOVID-19VaccinationEducational levelWomenCryptic population structure and transmission dynamics uncovered for Schistosoma mansoni populations by genetic analyses
Long J, Taylor S, Barbosa L, Silva L, Reis M, Blanton R. Cryptic population structure and transmission dynamics uncovered for Schistosoma mansoni populations by genetic analyses. Scientific Reports 2022, 12: 1059. PMID: 35058485, PMCID: PMC8776789, DOI: 10.1038/s41598-022-04776-0.Peer-Reviewed Original ResearchMicrobial source tracking and antimicrobial resistance in one river system of a rural community in Bahia, Brazil
Moretto V, Bartley P, Ferreira V, Santos C, Silva L, Ponce-Terashima R, Blanton R, Reis M, Barbosa L. Microbial source tracking and antimicrobial resistance in one river system of a rural community in Bahia, Brazil. Brazilian Journal Of Biology 2022, 82: e231838. PMID: 33681894, DOI: 10.1590/1519-6984.231838.Peer-Reviewed Original ResearchConceptsHuman fecal contaminationMicrobial source trackingRiver systemsFecal contaminationSource trackingGram-negative bacteriaGut of humansSpecies levelVillage centerWater supplyRiverRural communitiesNegative bacteriaBacteriaAntimicrobial resistanceNatural resistanceResidual antibioticsAntibiotic bacteriaHuman sourcesContaminationFood animalsBahiaClasses of antibioticsCommunityUse of antibiotics