2014
Anti-PR3 and anti-MPO antibodies are not present in sera of patients with pulmonary tuberculosis
Lima I, Oliveira R, Cabral M, Atta A, Marchi S, Reis E, Reis M, Barbosa L, Santiago M. Anti-PR3 and anti-MPO antibodies are not present in sera of patients with pulmonary tuberculosis. Rheumatology International 2014, 34: 1231-1234. PMID: 24719228, DOI: 10.1007/s00296-014-3009-z.Peer-Reviewed Original ResearchConceptsAnti-neutrophil cytoplasmic antibodiesAnti-PR3 antibodiesIndirect immunofluorescencePresence of ANCAPrevalence of ANCAInfectious diseasesComponents of neutrophilsGroup of patientsAnti-MPO antibodiesSera of patientsChest X-rayAnti-PR3Cytoplasmic antibodiesVasculitic syndromesTB patientsPulmonary tuberculosisAutoimmune disordersPresent studyClinical similaritiesSuch antibodiesPatientsELISA kitTuberculosisAntibodiesAutoantibodies
2011
TNF-alpha and IL-8: Serum levels and gene polymorphisms (−308G>A and −251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia
Cajado C, Cerqueira B, Couto F, Moura-Neto J, Vilas-Boas W, Dorea M, Lyra I, Barbosa C, Reis M, Goncalves M. TNF-alpha and IL-8: Serum levels and gene polymorphisms (−308G>A and −251A>T) are associated with classical biomarkers and medical history in children with sickle cell anemia. Cytokine 2011, 56: 312-317. PMID: 21802960, DOI: 10.1016/j.cyto.2011.07.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAllelesAnemia, Sickle CellBiomarkersCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayHaplotypesHumansInterleukin-8Medical History TakingPolymerase Chain ReactionPolymorphism, GeneticPolymorphism, Restriction Fragment LengthTumor Necrosis Factor-alphaConceptsSickle cell anemiaTNF-alpha -308GT gene polymorphismGene polymorphismsIL-8Serum levelsMedical historyTNF-alphaCell anemiaHigher TNF-alpha levelsIL-8 gene polymorphismsA alleleClassical biomarkersSteady-state sickle cell anemiaTNF-alpha levelsHeterogeneous clinical outcomesLogistic regression analysisYears of ageCytokine levelsClinical outcomesImmunological biomarkersHealthy controlsPatient outcomesInterleukin-8SCA patients
2010
Evaluating glutathione S‐Transferase (GST) null genotypes (GSTT1 and GSTM1) as a potential biomarker of predisposition for developing leukopenia
GONCALVES M, NETO J, SOUZA C, MELO P, REIS M. Evaluating glutathione S‐Transferase (GST) null genotypes (GSTT1 and GSTM1) as a potential biomarker of predisposition for developing leukopenia. International Journal Of Laboratory Hematology 2010, 32: e49-e56. PMID: 19555437, DOI: 10.1111/j.1751-553x.2009.01169.x.Peer-Reviewed Original ResearchConceptsGSTM1 null genotypeNull genotypeBiomarkers of susceptibilityWhite blood cell countGlutathione S-transferase null genotypeOccurrence of leukopeniaRisk of neutropeniaBlood cell countCase-control studyWhite blood cell deficiencyGlutathione S-transferaseGSTT1 null genotypeOxidative stress productsBlood cell deficiencyGSTM1 genotypeLeukopeniaNormal subjectsCell countPotential biomarkersNeutropeniaGSTT1BiomarkersStress productsRiskSubjects
2005
HEV, TTV and GBV-C/HGV markers in patients with acute viral hepatitis
Lyra A, Pinho J, Silva L, Sousa L, Saraceni C, Braga E, Pereira J, Zarife M, Reis M, Lyra L, da Silva L, Carrilho F. HEV, TTV and GBV-C/HGV markers in patients with acute viral hepatitis. Brazilian Journal Of Medical And Biological Research 2005, 38: 767-775. PMID: 15917959, DOI: 10.1590/s0100-879x2005000500015.Peer-Reviewed Original ResearchConceptsAnti-HEV IgMHepatitis AGenotype 1C hepatitisAcute hepatitisAcute viral hepatitis AAnti-HEV IgG antibodiesAcute hepatitis A casesPrevalence of HEVAcute hepatitis AAcute viral hepatitisHepatitis A casesViral hepatitis ATTV genotype 1HEV IgGHGV infectionHGV markersAminotransferase levelsHepatitis EViral hepatitisIgG antibodiesBlood donorsHepatitisHGV isolatesPatients