2023
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study
Pieri O, Bezerra F, Coelho P, Enk M, Favre T, Graeff-Teixeira C, Oliveira R, Reis M, Andrade L, Beck L, Favero V, Fialho T, Guimarães R, Oliveira B, Pascoal V, Pinheiro M, Santos R, Silva L, Siqueira I, Souza R, Katz N. Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0238-2022. PMID: 36700600, PMCID: PMC9870275, DOI: 10.1590/0037-8682-0238-2022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, HelminthBrazilFecesHumansPoint-of-Care SystemsPrevalenceSchistosoma mansoniSchistosomiasis mansoniSensitivity and SpecificityConceptsCathodic antigenKato-KatzUrine-based pointSchistosomiasis mansoni infectionDifferent prevalence estimatesCare diagnostic testsSchistosomiasis elimination programmesWorld Health OrganizationMansoni infectionMulticenter studyStool samplesUrine pointPrevalence estimatesS. mansoniElimination programInfection statusDiagnostic testsHealth OrganizationUrine samplesHelmintexAntigenInfectionPrevalenceMansoniCare
2019
Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses
Kikuti M, Tauro L, Moreira P, Nascimento L, Portilho M, Soares G, Weaver S, Reis M, Kitron U, Ribeiro G. Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses. International Journal Of Infectious Diseases 2019, 91: 38-43. PMID: 31704226, DOI: 10.1016/j.ijid.2019.11.001.Peer-Reviewed Original ResearchConceptsConvalescent samplesIgM enzymeRT-PCRZika virus transmissionNegative patientsCHIKV infectionAcute samplesZIKV casesConvalescent seraSurveillance studyCHIKV transmissionZika virusCHIKV casesDiagnostic performanceLow specificityVirus transmissionEquivocal resultsTest sensitivitySerumELISA specificityPatientsHigh rateDengueConcomitant transmissionMore equivocal resultsPerformance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
Leony L, Freitas N, Del-Rei R, Carneiro C, Reis A, Jansen A, Xavier S, Gomes Y, Silva E, Reis M, Fraga D, Celedon P, Zanchin N, Dantas-Torres F, Santos F. Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs. PLOS Neglected Tropical Diseases 2019, 13: e0007545. PMID: 31242195, PMCID: PMC6615644, DOI: 10.1371/journal.pntd.0007545.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, ProtozoanChagas DiseaseDog DiseasesDogsImmunoglobulin GRecombinant Fusion ProteinsROC CurveSensitivity and SpecificitySerologic TestsTrypanosoma cruziConceptsCruzi infectionIBMP-8.4Cruzi IgG antibodiesDiagnostic performanceTrypanosoma cruzi infectionAntigenic matrixIgG antibody detectionIBMP-8.3IBMP-8.1IBMP-8.2High diagnostic performanceSuperior diagnostic performanceIgG antibodiesChimeric antigenInfected dogsVisceral leishmaniasisEpidemiological studiesRecombinant chimeric proteinAntibody detectionInfectious diseasesTransmission riskSerological diagnosisDogsROC curveDiagnostic potential
2013
Antibodies to citrullinated peptides in tuberculosis
Lima I, Oliveira R, Atta A, Marchi S, Barbosa L, Reis E, Reis M, Santiago M. Antibodies to citrullinated peptides in tuberculosis. Clinical Rheumatology 2013, 32: 685-687. PMID: 23344687, DOI: 10.1007/s10067-013-2173-y.Peer-Reviewed Original ResearchConceptsAnti-citrullinated peptide antibodiesAnti-MCV antibodiesRheumatoid arthritisHealthy controlsRheumatoid factor positivityRA patientsSymmetric polyarthritisTB patientsPulmonary tuberculosisBone erosionCCP antibodyAutoimmune diseasesHigh incidencePeptide antibodiesPatientsControl groupHigh specificityTuberculosisInfectious diseasesAntibodiesPositivityDiseaseSpecificityMethodological factorsPolyarthritis
2001
Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis
Flannery B, Costa D, Carvalho F, Guerreiro H, Matsunaga J, Da Silva E, Ferreira A, Riley L, Reis M, Haake D, Ko A. Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis. Journal Of Clinical Microbiology 2001, 39: 3303-3310. PMID: 11526167, PMCID: PMC88335, DOI: 10.1128/jcm.39.9.3303-3310.2001.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, BacterialAntigens, BacterialEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin GLeptospiraLeptospirosisLipoproteinsRecombinant ProteinsSensitivity and SpecificityConceptsEnzyme-linked immunosorbent assayIgG enzyme-linked immunosorbent assaySerodiagnosis of leptospirosisHealthy individualsImmunosorbent assayTest-positive individualsCases of leptospirosisHigh-incidence regionsLyme disease patientsMicroscopic agglutination testConvalescent phaseHepatitis patientsAcute phaseDengue patientsDisease patientsPatient seraHealthy residentsLeptospira antigensCutoff valueDiagnostic utilityPatientsAgglutination testUseful antigenLeptospirosisAntigen