Evaluating glutathione S‐Transferase (GST) null genotypes (GSTT1 and GSTM1) as a potential biomarker of predisposition for developing leukopenia
GONCALVES M, NETO J, SOUZA C, MELO P, REIS M. Evaluating glutathione S‐Transferase (GST) null genotypes (GSTT1 and GSTM1) as a potential biomarker of predisposition for developing leukopenia. International Journal Of Laboratory Hematology 2010, 32: e49-e56. PMID: 19555437, DOI: 10.1111/j.1751-553x.2009.01169.x.Peer-Reviewed Original ResearchConceptsGSTM1 null genotypeNull genotypeBiomarkers of susceptibilityWhite blood cell countGlutathione S-transferase null genotypeOccurrence of leukopeniaRisk of neutropeniaBlood cell countCase-control studyWhite blood cell deficiencyGlutathione S-transferaseGSTT1 null genotypeOxidative stress productsBlood cell deficiencyGSTM1 genotypeLeukopeniaNormal subjectsCell countPotential biomarkersNeutropeniaGSTT1BiomarkersStress productsRiskSubjects