2020
Accuracy of the Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay from the Centers for Disease Control and Prevention (CDC Zika MAC-ELISA) for Diagnosis of Zika Virus Infection
Portilho M, de Moraes L, Kikuti M, Nascimento L, Reis M, Boaventura V, Khouri R, Ribeiro G. Accuracy of the Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay from the Centers for Disease Control and Prevention (CDC Zika MAC-ELISA) for Diagnosis of Zika Virus Infection. Diagnostics 2020, 10: 835. PMID: 33080935, PMCID: PMC7603149, DOI: 10.3390/diagnostics10100835.Peer-Reviewed Original ResearchDays post-symptom onsetZika virus infectionConvalescent-phase seraVirus infectionRT-PCRDengue virusSerological diagnosisDengue casesPost-symptom onsetConvalescent-phase samplesBlood donor samplesIgM antibody capture enzymeEnzyme-linked immunosorbent assayZika IgM antibodySymptom onsetDENV infectionIgM antibodiesZIKV infectionBlood donorsDonor samplesCapture enzymeOutbreak investigationDisease controlInfectionImmunosorbent assay
2019
Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
Leony L, Freitas N, Del-Rei R, Carneiro C, Reis A, Jansen A, Xavier S, Gomes Y, Silva E, Reis M, Fraga D, Celedon P, Zanchin N, Dantas-Torres F, Santos F. Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs. PLOS Neglected Tropical Diseases 2019, 13: e0007545. PMID: 31242195, PMCID: PMC6615644, DOI: 10.1371/journal.pntd.0007545.Peer-Reviewed Original ResearchConceptsCruzi infectionIBMP-8.4Cruzi IgG antibodiesDiagnostic performanceTrypanosoma cruzi infectionAntigenic matrixIgG antibody detectionIBMP-8.3IBMP-8.1IBMP-8.2High diagnostic performanceSuperior diagnostic performanceIgG antibodiesChimeric antigenInfected dogsVisceral leishmaniasisEpidemiological studiesRecombinant chimeric proteinAntibody detectionInfectious diseasesTransmission riskSerological diagnosisDogsROC curveDiagnostic potential