2023
Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study
Barbosa L, Santiago M, Moretto V, Athanazio D, Takahashi D, Reis E, Lopes M, Lemaire D, Reis M. Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study. Brazilian Journal Of Biology 2023, 83: e244123. PMID: 34161457, DOI: 10.1590/1519-6984.244123.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusToll-like receptor 9TLR9 polymorphismsSLE patientsLupus erythematosusSingle nucleotide polymorphismsToll-like receptor 9 polymorphismsControl groupTLR9 single nucleotide polymorphismsSLE patient groupInnate immune systemDiscoid rashSLE populationClinical manifestationsPatient groupAutoimmune diseasesReceptor 9Brazilian patientsTLR9 geneImmune systemPatientsPilot studyAllele GAllele CGenotype frequencies
2007
Detection of antinucleosome antibodies in systemic lupus erythematosus
Lima I, Barbosa L, Lopes M, Reis E, Reis M, Colossi K, Abreu M, Ferreira C, Santiago M. Detection of antinucleosome antibodies in systemic lupus erythematosus. Advances In Rheumatology 2007, 47: 160-164. DOI: 10.1590/s0482-50042007000300004.Peer-Reviewed Original ResearchDiagnosis of SLESystemic lupus erythematosusSystemic sclerosisDisease activitySLEDAI scoreLupus erythematosusAntinucleosome antibodiesSLE samplesDisease activity indexCross-sectional studyAnti-DNA antibodiesMean age 35Lack of associationMyositis patientsRheumatology criteriaRheumatologic practiceSLE patientsAge 35American CollegeActivity indexPatientsDiagnosisAntibodiesDiagnostic performanceELISA system
2006
Uso do rituximabe para o tratamento da plaquetopenia do lúpus eritematoso sistêmico: eficácia clínica e efeito nas moléculas de co-estimulação
Santiago M, Reis E, Lima I, Reis M. Uso do rituximabe para o tratamento da plaquetopenia do lúpus eritematoso sistêmico: eficácia clínica e efeito nas moléculas de co-estimulação. Advances In Rheumatology 2006, 46: 153-156. DOI: 10.1590/s0482-50042006000200013.Peer-Reviewed Original ResearchSystemic lupus erythematosusCases of SLEInfusions of rituximabUse of prednisoneUse of corticosteroidsLúpus eritematoso sistêmicoIntravenous immunoglobulinSLE patientsRare complicationLupus erythematosusImmunosuppressive drugsPersistent thrombocytopeniaCostimulatory moleculesPeripheral bloodSide effectsB cellsRituximabThrombocytopeniaCytometry analysisPatientsInfusionAzathioprineCorticosteroidsErythematosusPrednisone