2022
Evaluation of the impact of chemical control on the ecology of Rattus norvegicus of an urban community in Salvador, Brazil
Pertile A, Lustosa R, Carvalho-Pereira T, Pedra G, Panti-May J, Oliveira U, Zeppelini C, Souza F, Oliveira D, Khalil H, Reis M, Childs J, Ko A, Begon M, Costa F. Evaluation of the impact of chemical control on the ecology of Rattus norvegicus of an urban community in Salvador, Brazil. PLOS ONE 2022, 17: e0270568. PMID: 35857771, PMCID: PMC9299319, DOI: 10.1371/journal.pone.0270568.Peer-Reviewed Original ResearchConceptsRodent control programsDemographic variablesSpirochete Leptospira interrogansControl interventionsCommunity settingsR. norvegicusChi-squareControl of zoonosesLeptospira interrogansChemical interventionDemographic characteristicsInterventionIntervention campaignsRodentsSynanthropic rodentsMonthsBody massControl programsControl practicesRattus norvegicusControl campaignsUrban poor communitiesPopulationEnvironmental transmissionAnalysis of varianceBiannual and Quarterly Comparison Analysis of Agglutinating Antibody Kinetics on a Subcohort of Individuals Exposed to Leptospira interrogans in Salvador, Brazil
Cruz J, Nery N, Sacramento G, Victoriano R, Montenegro A, Santana J, Costa F, Ko A, Reis M, Wunder E. Biannual and Quarterly Comparison Analysis of Agglutinating Antibody Kinetics on a Subcohort of Individuals Exposed to Leptospira interrogans in Salvador, Brazil. Frontiers In Medicine 2022, 9: 862378. PMID: 35492362, PMCID: PMC9048256, DOI: 10.3389/fmed.2022.862378.Peer-Reviewed Original ResearchMicroscopic agglutination testAntibody kineticsEndemic areasReinfection eventsSubcohort of individualsBurden of leptospirosisLife-threatening diseaseProspective cohortClinical manifestationsAsymptomatic infectionHumoral responseRisk factorsImmune responseLeptospirosis infectionAgglutination testPaucity of informationSerological surveyLeptospirosisSample collection timeInfectionLeptospira interrogansSubcohortFurther studiesHigh rateDisease
2021
Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs
Santos A, dos Santos Ribeiro P, da França G, Souza F, Ramos E, Figueira C, Reis M, Costa F, Ristow P. Leptospira interrogans biofilm formation in Rattus norvegicus (Norway rats) natural reservoirs. PLOS Neglected Tropical Diseases 2021, 15: e0009736. PMID: 34495971, PMCID: PMC8451993, DOI: 10.1371/journal.pntd.0009736.Peer-Reviewed Original ResearchConceptsRenal tubulesPathogenic LeptospiraPathogenesis of leptospirosisMain reservoir hostsNatural animal reservoirsBacterial carriageChronic colonizationLeptospiral colonizationRenal carriageAnimal reservoirsLeptospira interrogansLeptospirosisUrban slumsCausative agentLeptospiraTubulesPossible roleReservoir hostsCarriageNatural reservoirBiofilm formationOcclusion patternsBacterial survivalHost reservoirsR. norvegicus
2017
A survey of zoonotic pathogens carried by house mouse and black rat populations in Yucatan, Mexico
PANTI-MAY J, DE ANDRADE R, GURUBEL-GONZÁLEZ Y, PALOMO-ARJONA E, SODÁ-TAMAYO L, MEZA-SULÚ J, RAMÍREZ-SIERRA M, DUMONTEIL E, VIDAL-MARTÍNEZ V, MACHAÍN-WILLIAMS C, DE OLIVEIRA D, REIS M, TORRES-CASTRO M, ROBLES M, HERNÁNDEZ-BETANCOURT S, COSTA F. A survey of zoonotic pathogens carried by house mouse and black rat populations in Yucatan, Mexico. Epidemiology And Infection 2017, 145: 2287-2295. PMID: 28689507, PMCID: PMC6231242, DOI: 10.1017/s0950268817001352.Peer-Reviewed Original ResearchConceptsH. diminutaZoonotic pathogensPolymerase chain reactionRatsMiceTropical diseasesCruzi DNALeptospira interrogansChain reactionL. interrogansT. cruziFurther studiesHymenolepis diminutaPublic healthReservoir hostsTrypanosoma cruziSedimentation techniqueInterrogansPathogensHouse miceCruziDiminutaImportant reservoirEpidemiologyPrevalence
2007
Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection
de Faria M, Athanazio DA, Ramos E, Silva EF, Reis MG, Ko AI. Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection. Journal Of Comparative Pathology 2007, 137: 231-238. PMID: 17996544, DOI: 10.1016/j.jcpa.2007.08.001.Peer-Reviewed Original ResearchConceptsInterstitial nephritisPathology of leptospirosisKidneys of ratsMorphological alterationsPathogenesis of leptospirosisFiocruz L1-130Leptospiral diseaseWistar ratsLeptospira infectionPathological changesUrban outbreaksRecreational exposureHuman infectionsL1-130RatsWidespread anthropozoonosisKidneyLeptospira interrogansLeptospirosisNephritisInfectionDiseaseEmergent diseaseMammalian reservoirsHost resistance
2001
Identification of New Repetitive Element inLeptospira interrogans Serovar Copenhageni and Its Application to PCR-Based Differentiation ofLeptospira Serogroups
Barocchi M, Ko A, Ferrer S, Faria M, Reis M, Riley L. Identification of New Repetitive Element inLeptospira interrogans Serovar Copenhageni and Its Application to PCR-Based Differentiation ofLeptospira Serogroups. Journal Of Clinical Microbiology 2001, 39: 191-195. PMID: 11136769, PMCID: PMC87700, DOI: 10.1128/jcm.39.1.191-195.2001.Peer-Reviewed Original Research