2023
Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study
Barbosa L, Santiago M, Moretto V, Athanazio D, Takahashi D, Reis E, Lopes M, Lemaire D, Reis M. Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study. Brazilian Journal Of Biology 2023, 83: e244123. PMID: 34161457, DOI: 10.1590/1519-6984.244123.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusToll-like receptor 9TLR9 polymorphismsSLE patientsLupus erythematosusSingle nucleotide polymorphismsToll-like receptor 9 polymorphismsControl groupTLR9 single nucleotide polymorphismsSLE patient groupInnate immune systemDiscoid rashSLE populationClinical manifestationsPatient groupAutoimmune diseasesReceptor 9Brazilian patientsTLR9 geneImmune systemPatientsPilot studyAllele GAllele CGenotype frequencies
2013
Antibodies to citrullinated peptides in tuberculosis
Lima I, Oliveira R, Atta A, Marchi S, Barbosa L, Reis E, Reis M, Santiago M. Antibodies to citrullinated peptides in tuberculosis. Clinical Rheumatology 2013, 32: 685-687. PMID: 23344687, DOI: 10.1007/s10067-013-2173-y.Peer-Reviewed Original ResearchConceptsAnti-citrullinated peptide antibodiesAnti-MCV antibodiesRheumatoid arthritisHealthy controlsRheumatoid factor positivityRA patientsSymmetric polyarthritisTB patientsPulmonary tuberculosisBone erosionCCP antibodyAutoimmune diseasesHigh incidencePeptide antibodiesPatientsControl groupHigh specificityTuberculosisInfectious diseasesAntibodiesPositivityDiseaseSpecificityMethodological factorsPolyarthritis
2011
Lymphocyte Surface Molecule Expression on Basal State and After Challenge: Association of Clinical Profile, Inflammation, Hematological and Biochemical Markers in Sickle Cell Anemia Patients
Cerqueira B, Vilas-Boas W, Zanette A, Clarencio J, Salvino M, Cezar R, Andrade D, Reis M, Goncalves M. Lymphocyte Surface Molecule Expression on Basal State and After Challenge: Association of Clinical Profile, Inflammation, Hematological and Biochemical Markers in Sickle Cell Anemia Patients. Blood 2011, 118: 2146. DOI: 10.1182/blood.v118.21.2146.2146.Peer-Reviewed Original ResearchSickle cell anemia patientsSoluble adhesion moleculesSickle cell anemiaSurface molecule expressionSCA patientsControl groupAnemia patientsAdhesion moleculesLymphocyte expressionLPS challengeMedical historyCD18 expressionMolecule expressionSoluble vascular adhesion moleculeBasal statePro-inflammatory interactionsEffector immune responsesVaso-occlusive episodesExpression of CD62LMarkers of inflammationChronic inflammatory stateTNF-alpha valuesVascular adhesion moleculesComplete medical historyExpression of CD11b
2010
CD32, CD18, CD11b and CD62L Expression on Monocyte without and After Lipopolysaccharide (LPS) Challenge: Association with Inflammatory and Hemolysis Markers In Sickle Cell Anemia.
Cerqueira B, Vilas-Boas W, Neto J, Clarencio J, Andrade D, Cezar R, Zanette A, Reis M, Goncalves M. CD32, CD18, CD11b and CD62L Expression on Monocyte without and After Lipopolysaccharide (LPS) Challenge: Association with Inflammatory and Hemolysis Markers In Sickle Cell Anemia. Blood 2010, 116: 1655. DOI: 10.1182/blood.v116.21.1655.1655.Peer-Reviewed Original ResearchSickle cell anemiaVaso-occlusive episodesExpression of CD11bMonocyte expressionSCA patientsControl groupCell anemiaRed blood cellsMedical historyLipid metabolismHemoglobin SMarkers of hemolysisSurface molecule expressionComplete medical historySurface moleculesMonocyte surface moleculesSickle red blood cellsProinflammatory interactionsCD62L expressionOutpatient clinicCD32 expressionVascular occlusionHemolysis markersSplenic sequestrationTNF-alpha
2009
Adhesion Molecules Interaction with Markers of Lipid Metabolism, Hemolysis, Endothelial Dysfunction and Medical Histories Among Steady-State Sickle Cell Anemia Patients.
Cerqueira B, Boas W, Clarêncio J, Andrade D, Zanette A, Reis M, Neto J, Cesar R, Goncalves M. Adhesion Molecules Interaction with Markers of Lipid Metabolism, Hemolysis, Endothelial Dysfunction and Medical Histories Among Steady-State Sickle Cell Anemia Patients. Blood 2009, 114: 2553. DOI: 10.1182/blood.v114.22.2553.2553.Peer-Reviewed Original ResearchSickle cell anemia patientsSickle cell anemiaSoluble adhesion moleculesHigher serum levelsMedical historyAnemia patientsAdhesion moleculesEndothelial dysfunctionSerum levelsICAM-1Aspartate transferaseSteady-state sickle cell anemia patientsDensity lipoproteinControl groupVCAM-1 adhesion moleculesLipid metabolismChronic clinical complicationsVaso-occlusive painSurface adhesion molecule expressionNeutrophil adhesion moleculesSoluble ICAM-1Complete medical historyAdhesion molecule expressionHigh-density lipoproteinLow-density lipoprotein
2008
Polymorphisms in the glutathione S-transferase theta and mu genes and susceptibility to myeloid leukemia in Brazilian patients
Souza C, Barbosa C, de Moura Neto J, Barreto J, Reis M, Gonçalves M. Polymorphisms in the glutathione S-transferase theta and mu genes and susceptibility to myeloid leukemia in Brazilian patients. Genetics And Molecular Biology 2008, 31: 39-41. DOI: 10.1590/s1415-47572008000100008.Peer-Reviewed Original ResearchChronic myeloid leukemiaAcute promyelocytic leukemiaRisk factorsMyeloid leukemiaTypes of leukemiaGlutathione S-transferase thetaGSTT1null genotypeAPL patientsGSTM1 polymorphismHealthy controlsBrazilian patientsPromyelocytic leukemiaNull genotypeControl groupGene polymorphismsGSTT1 genesLeukemiaPatientsMultiplex PCRPolymorphismDifferent populationsAssociation studiesGroup