2019
Oropharyngeal Oxygen Concentration Is Dependent on the Oxygen Mask System and Sampling Location.
Yanez ND, Fu AY, Treggiari MM, Kirsch JR. Oropharyngeal Oxygen Concentration Is Dependent on the Oxygen Mask System and Sampling Location. Respiratory Care 2019, 65: 29-35. PMID: 31506337, DOI: 10.4187/respcare.07027.Peer-Reviewed Original Research
2012
Targeting Brain Tissue Oxygenation in Traumatic Brain Injury
Martini RP, Deem S, Treggiari MM. Targeting Brain Tissue Oxygenation in Traumatic Brain Injury. Respiratory Care 2012, 58: 162-172. PMID: 23271826, DOI: 10.4187/respcare.01942.Peer-Reviewed Original ResearchConceptsBrain tissue oxygenationTraumatic brain injuryBrain injuryTissue oxygenationBrain tissue oxygenation monitoringManagement of patientsTissue oxygenation monitoringInvasive monitoring devicesPoor prognosisProspective studyRetrospective studyTherapy resultsPrognostic informationOxygenation monitoringOutcome differencesTherapeutic interventionsPhysiologic manipulationsOxygen challengeInjuryOxygenationAccepted practicePatientsPrognosisTherapyTrials
2009
Management guided by brain tissue oxygen monitoring and outcome following severe traumatic brain injury.
Martini RP, Deem S, Yanez ND, Chesnut RM, Weiss NS, Daniel S, Souter M, Treggiari MM. Management guided by brain tissue oxygen monitoring and outcome following severe traumatic brain injury. Journal Of Neurosurgery 2009, 111: 644-9. PMID: 19392603, DOI: 10.3171/2009.2.jns08998.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainBrain InjuriesCohort StudiesFemaleHealth ResourcesHospital CostsHospital MortalityHumansIntracranial PressureLength of StayMaleMiddle AgedMonitoring, PhysiologicOxygenPrognosisRegression AnalysisRespiration, ArtificialRetrospective StudiesTrauma Severity IndicesTreatment OutcomeConceptsBrain tissue oxygen monitoringHospital mortality rateTissue oxygen monitoringTraumatic brain injurySevere traumatic brain injuryMortality rateBrain injuryHospital lengthNeurological outcomeHospital dischargeClinical managementICP monitoringMedian hospital lengthWorse neurological outcomeHospital resource utilizationOxygen monitoringMain outcome measuresFunctional Independence ScoreIntracranial pressure monitoringSeverity of injuryBaseline characteristicsCohort studyPatient ageMore patientsOsmotic therapy
2008
Tezosentan normalizes hepatomesenteric perfusion in a porcine model of cardiac tamponade
ÅNEMAN A, TREGGIARI MM, BURGENER D, LAESSER M, STRASSER S, HADENGUE A. Tezosentan normalizes hepatomesenteric perfusion in a porcine model of cardiac tamponade. Acta Anaesthesiologica Scandinavica 2008, 53: 203-209. PMID: 19094177, DOI: 10.1111/j.1399-6576.2008.01834.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarbon DioxideCardiac Output, LowCardiac TamponadeDrug Evaluation, PreclinicalEndothelin Receptor AntagonistsEndothelin-1FemaleLactatesLiver CirculationMaleModels, AnimalOxygenOxygen ConsumptionPyridinesSplanchnic CirculationSus scrofaTetrazolesVascular ResistanceVasoconstrictionConceptsLaser Doppler flowMesenteric oxygen deliveryLow CO stateBaseline valuesCardiac tamponadeOxygen deliveryBlood flowPorcine modelPortal venous blood flowHepatic artery blood flowLow cardiac output stateET-1 blockadeMesenteric oxygen extractionMesenteric vascular resistanceArtery blood flowCardiac output stateNormal saline vehicleVenous blood flowMesenteric vasoconstrictionPortal pressureSplanchnic hypoperfusionVascular resistanceHepatic arterialEndothelin-1Liver protection