2019
Inhaled Iloprost Versus Epoprostenol in Heart Transplant Recipients
Enomoto TM, Treggiari MM, Yanez ND, Merkel MJ. Inhaled Iloprost Versus Epoprostenol in Heart Transplant Recipients. Respiratory Care 2019, 64: 743-751. PMID: 30967439, DOI: 10.4187/respcare.06426.Peer-Reviewed Original ResearchConceptsAcute right ventricular dysfunctionHeart transplant recipientsRight ventricular dysfunctionMechanical ventilationEnd pointHeart transplantationHospital stayTransplant recipientsVentricular dysfunctionHemodynamic valuesMedian numberAcute pulmonary hypertensionLength of ICUOrthotopic heart transplantationPrimary end pointSafety end pointSecondary end pointsImmediate postoperative periodPrimary vasodilatorVasoactive medicationsVasodilatory therapyPostoperative bleedingPulmonary hypertensionPostoperative periodConsecutive patients
2017
Process Improvement Initiative for the Perioperative Management of Patients With a Cardiovascular Implantable Electronic Device
Ellis MKM, Treggiari MM, Robertson JM, Rozner MA, Graven PF, Aziz MF, Merkel MJ, Kahl EA, Cohen NA, Stecker EC, Schulman PM. Process Improvement Initiative for the Perioperative Management of Patients With a Cardiovascular Implantable Electronic Device. Anesthesia & Analgesia 2017, 125: 58-65. PMID: 28319519, DOI: 10.1213/ane.0000000000001953.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overCardiac Surgical ProceduresCardiovascular SystemCohort StudiesDefibrillators, ImplantableFemaleHealth Care CostsHumansMaleMiddle AgedOperating RoomsOutcome and Process Assessment, Health CarePacemaker, ArtificialPatient SafetyPerioperative CarePerioperative PeriodRisk AssessmentTime FactorsConceptsCardiovascular implantable electronic devicesSafe perioperative carePreintervention periodPostintervention periodImplantable electronic devicesPerioperative carePerioperative surgical home modelPrimary end pointCohort of patientsSame eligibility criteriaLarge academic medical centerPatient Safety DatabaseImprovement initiativesAcademic medical centerAdequate patient safetyNew care modelsImproved operating room efficiencyBaseline characteristicsAdverse eventsPerioperative managementPotential confoundersConcurrent cohortDay surgerySurgical proceduresCare modelAn Initiative to Optimize Waste Streams in the Operating Room: RECycling in the Operating Room (RECOR) Project.
Martin DM, Yanez ND, Treggiari MM. An Initiative to Optimize Waste Streams in the Operating Room: RECycling in the Operating Room (RECOR) Project. AANA Journal 2017, 85: 108-12. PMID: 30501159.Peer-Reviewed Original ResearchMeSH KeywordsHumansNurse AnesthetistsOperating RoomsOutcome and Process Assessment, Health CareRecyclingRefuse DisposalWashington
2014
Long-Term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia*
Khandelwal N, Hough CL, Bansal A, Veenstra DL, Treggiari MM. Long-Term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia*. Critical Care Medicine 2014, 42: 1610-1618. PMID: 24732240, PMCID: PMC4061153, DOI: 10.1097/ccm.0000000000000322.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedCritical CareFemaleHospital CostsHospitals, UniversityHumansHypoxiaLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePatient DischargeSevere Acute Respiratory SyndromeSex FactorsSocioeconomic FactorsTime FactorsTrauma CentersConceptsSevere acute respiratory distress syndromeAcute respiratory distress syndromeRespiratory distress syndromeLong-term survivalRescue therapyProportional hazards modelHospital mortalityDistress syndromeICU admissionHazard ratioHospital dischargeSevere acute respiratory distress syndrome (ARDS) patientsAcute respiratory distress syndrome survivorsConventional treatmentAcute respiratory distress syndrome patientsPaO2/FiO2 ratioBetter long-term survivalRespiratory distress syndrome patientsLevel 1 trauma centerMeeting study inclusion criteriaCox proportional hazards modelHigher hospital mortalityKaplan-Meier methodState death registryStudy inclusion criteriaImproved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation
Dale CR, Kannas DA, Fan VS, Daniel SL, Deem S, Yanez ND, Hough CL, Dellit TH, Treggiari MM. Improved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation. Annals Of The American Thoracic Society 2014, 11: 367-374. PMID: 24597599, PMCID: PMC4028734, DOI: 10.1513/annalsats.201306-210oc.Peer-Reviewed Original ResearchConceptsCAM-ICU assessmentsIntensive care unitMechanical ventilationMedian durationICU stayBenzodiazepine doseSedation protocolPatient assessmentBaseline cohortTrauma-surgical intensive care unitConfusion Assessment Method-ICURichmond Agitation-Sedation Scale scorePrespecified secondary endpointSedation Scale scoreDays of deliriumImproved patient outcomesMultivariable linear regressionBenzodiazepine dosingBenzodiazepine exposureDelirium protocolHospital mortalityPneumonia ratesProtocol cohortRASS assessmentsImproved analgesia
2007
Effect of Intensive Care Unit Organizational Model and Structure on Outcomes in Patients with Acute Lung Injury
Treggiari MM, Martin DP, Yanez ND, Caldwell E, Hudson LD, Rubenfeld GD. Effect of Intensive Care Unit Organizational Model and Structure on Outcomes in Patients with Acute Lung Injury. American Journal Of Respiratory And Critical Care Medicine 2007, 176: 685-690. PMID: 17556721, PMCID: PMC1994237, DOI: 10.1164/rccm.200701-165oc.Peer-Reviewed Original ResearchMeSH KeywordsAPACHEHospital MortalityHumansIntensive Care UnitsModels, OrganizationalOutcome and Process Assessment, Health CarePersonnel Staffing and SchedulingPhysician ExecutivesRespiratory Distress SyndromeSurveys and QuestionnairesTreatment OutcomeConceptsAcute lung injuryClosed ICUOpen ICUHospital mortalityLung injuryData support recommendationsPopulation-based cohortPatient care practicesComplete survey dataAdult ICUsCohort studyImproved mortalityIll patientsIntensive careMain endpointPatient mortalityPotential confoundersHigher physicianICUICU structurePatient transferPatientsCare practicesSelf-administered mail questionnaireNurse availability
2005
Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department
Merlani PG, Pasquina P, Granier JM, Treggiari M, Rutschmann O, Ricou B. Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department. Academic Emergency Medicine 2005, 12: 1206-1215. PMID: 16293895, DOI: 10.1197/j.aem.2005.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedEmergency Service, HospitalFemaleHospitalizationHumansIntubation, IntratrachealMaleMultivariate AnalysisOutcome and Process Assessment, Health CarePositive-Pressure RespirationPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsSensitivity and SpecificitySurvival AnalysisSwitzerlandTreatment FailureConceptsNoninvasive positive pressure ventilationFailure of NPPVAcute respiratory failurePositive pressure ventilationEmergency departmentRespiratory rateRespiratory failurePressure ventilationEndotracheal intubationNPPV failureGlasgow Coma Scale scoreSubsequent endotracheal intubationNegative predictive valueED admissionInstitutional protocolFactors AssociatedPatientsPredictive valueScale scoreMultivariate analysisIntubationVentilationFailureHoursDepartment