Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response
Gozzoli V, Treggiari MM, Kleger GR, Roux-Lombard P, Fathi M, Pichard C, Romand JA. Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response. Intensive Care Medicine 2004, 30: 401-407. PMID: 14722642, DOI: 10.1007/s00134-003-2087-2.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAnalgesics, Non-NarcoticAnalysis of VarianceBody TemperatureCryotherapyCytokinesDipyroneFemaleFeverHemodynamicsHumansMaleMetabolismMiddle AgedSystemic Inflammatory Response SyndromeTime FactorsConceptsCytokine concentrationsInflammatory responseEffects of antipyresisMean arterial pressureTertiary university hospitalC-reactive proteinEnergy expenditure indexUndesirable hemodynamic effectsBody temperatureIntravenous propacetamolMetamizol groupPropacetamol groupHemodynamic effectsSurgical ICUArterial pressureIll patientsUrine outputUnstable patientsHemodynamic variablesUniversity HospitalInterleukin-6Physical therapyTreatment groupsPropacetamolMetamizol