2016
Comparison of enteral ethanol and benzodiazepines for alcohol withdrawal in neurocritical care patients
Gipson G, Tran K, Hoang C, Treggiari M. Comparison of enteral ethanol and benzodiazepines for alcohol withdrawal in neurocritical care patients. Journal Of Clinical Neuroscience 2016, 31: 88-91. PMID: 27262870, DOI: 10.1016/j.jocn.2016.02.028.Peer-Reviewed Original ResearchConceptsEnteral ethanolCIWA scoreAlcohol withdrawalEthanol groupIntensive care unit lengthClinical Institute Withdrawal AssessmentAlcohol withdrawal managementRetrospective chart reviewNeurocritical care patientsGlasgow Coma ScaleLength of stayUse of benzodiazepinesLevel of comaAlcohol scale scoresPrimary endpointSecondary endpointsChart reviewClinical characteristicsFirst medicationCare patientsComa ScaleOral intakeEthanol withdrawalWithdrawal AssessmentNeurocritical care
2014
Improved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation
Dale CR, Kannas DA, Fan VS, Daniel SL, Deem S, Yanez ND, Hough CL, Dellit TH, Treggiari MM. Improved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation. Annals Of The American Thoracic Society 2014, 11: 367-374. PMID: 24597599, PMCID: PMC4028734, DOI: 10.1513/annalsats.201306-210oc.Peer-Reviewed Original ResearchConceptsCAM-ICU assessmentsIntensive care unitMechanical ventilationMedian durationICU stayBenzodiazepine doseSedation protocolPatient assessmentBaseline cohortTrauma-surgical intensive care unitConfusion Assessment Method-ICURichmond Agitation-Sedation Scale scorePrespecified secondary endpointSedation Scale scoreDays of deliriumImproved patient outcomesMultivariable linear regressionBenzodiazepine dosingBenzodiazepine exposureDelirium protocolHospital mortalityPneumonia ratesProtocol cohortRASS assessmentsImproved analgesia