2022
Pharmacokinetics and Tolerability of Intraperitoneal Chloroprocaine After Fetal Extraction in Women Undergoing Cesarean Delivery
Togioka BM, Zarnegarnia Y, Bleyle LA, Koop D, Brookfield K, Yanez ND, Treggiari MM. Pharmacokinetics and Tolerability of Intraperitoneal Chloroprocaine After Fetal Extraction in Women Undergoing Cesarean Delivery. Anesthesia & Analgesia 2022, 135: 777-786. PMID: 35544759, DOI: 10.1213/ane.0000000000006064.Peer-Reviewed Original ResearchConceptsLocal anesthetic systemic toxicityPeak plasma concentrationCesarean deliveryPlasma concentrationsSystemic toxicityIntraperitoneal administrationFetal extractionMultiple-dose escalation studyPatient drug exposureMaternal blood samplesMaximum plasma concentrationRoute of administrationYears of ageClinical tolerabilityEscalation studySpinal anesthesiaUterine closureNeuraxial anesthesiaClinical symptomsDrug exposureClinical signsWomen 18Prospective assessmentBlood samplesPharmacokinetic profile
2020
Labor Epidural Education and Hispanic Ethnicity: Reply.
Togioka BM, Yanez ND, Treggiari MM. Labor Epidural Education and Hispanic Ethnicity: Reply. Anesthesiology 2020, 132: 1284-1285. PMID: 32101970, DOI: 10.1097/aln.0000000000003201.Peer-Reviewed Original Research
2019
Education Program Regarding Labor Epidurals Increases Utilization by Hispanic Medicaid Beneficiaries: A Randomized Controlled Trial.
Togioka BM, Seligman KM, Werntz MK, Yanez ND, Noles LM, Treggiari MM. Education Program Regarding Labor Epidurals Increases Utilization by Hispanic Medicaid Beneficiaries: A Randomized Controlled Trial. Anesthesiology 2019, 131: 840-849. PMID: 31299658, DOI: 10.1097/aln.0000000000002868.Peer-Reviewed Original ResearchConceptsRoutine care groupEpidural labor analgesiaNon-Hispanic womenNon-Hispanic cohortsRoutine careHispanic womenEpidural analgesiaLabor analgesiaEpidural useCare groupLabor epiduralsMedicaid beneficiariesNon-Hispanic ethnicityPrimary endpointSecondary endpointsAdverse eventsControlled TrialsObstetric providersEducational programsIntervention groupAcademic hospitalIndependent cohortAnalgesiaPerson counselingHealthcare disparities