2015
Patient-Level Interventions to Prevent the Acquisition of Resistant Gram-Negative Bacteria in Critically Ill Patients: A Systematic Review
Zaky A, Zeliadt SB, Treggiari MM. Patient-Level Interventions to Prevent the Acquisition of Resistant Gram-Negative Bacteria in Critically Ill Patients: A Systematic Review. Anaesthesia And Intensive Care 2015, 43: 23-33. PMID: 25579286, DOI: 10.1177/0310057x1504300105.Peer-Reviewed Original ResearchConceptsPatient-level interventionsIntensive care unitMDR-GNBCare unitSystematic reviewMultidrug-resistant Gram-negative bacterial infectionsSelective digestive decontaminationComparative interventional studyGram-negative bacterial infectionsInfection control effortsResistant Gram-negative bacteriaRate of infectionPrevention of colonisationDigestive decontaminationInterventional trialsIll patientsInterventional studyAnalysed trialsControl groupBacterial infectionsInfectionInterventionTrialsSignificant reductionScience databases
2008
Effects of Anemia and Hypotension on Porcine Optic Nerve Blood Flow and Oxygen Delivery
Lee LA, Deem S, Glenny RW, Townsend I, Moulding J, An D, Treggiari MM, Lam A. Effects of Anemia and Hypotension on Porcine Optic Nerve Blood Flow and Oxygen Delivery. Anesthesiology 2008, 108: 864-872. PMID: 18431122, DOI: 10.1097/aln.0b013e31816c8a30.Peer-Reviewed Original ResearchConceptsCerebral blood flowOptic nerve blood flowNerve blood flowBlood flowCerebral DO2Venous congestionHypovolemic hypotensionOxygen deliveryPerioperative ischemic optic neuropathyCompensatory mechanismsStable cerebral blood flowIschemic optic neuropathyMajor surgical proceduresEffect of anemiaConditions of hypotensionSignificant reductionOptic neuropathyHypotensionSurgical proceduresControl animalsAnemiaFarm-raised pigsPhysiologic perturbationsDO2Significant increase