2020
Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia
Martini RP, Yanez ND, Treggiari MM, Tekkali P, Soelberg C, Aziz MF. Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia. BMC Anesthesiology 2020, 20: 211. PMID: 32838740, PMCID: PMC7446207, DOI: 10.1186/s12871-020-01117-4.Peer-Reviewed Original ResearchConceptsPostoperative pneumoniaSubgroup of patientsBaseline cohortSurgical patientsIntervention cohortEndotracheal intubationOdds ratioNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectUnselected surgical populationUnadjusted odds ratioHigh-risk populationPatient-level dataRisk of ventilatorQuality improvement projectInterrupted time series designElectronic health recordsHospital mortalityVAP bundleSurgical populationPatient characteristicsPneumonia riskHistoric cohortHospital admissionFurther risk reduction
2016
Randomized Pilot Trial of Two Modified Endotracheal Tubes To Prevent Ventilator-associated Pneumonia
Deem S, Yanez D, Sissons-Ross L, Broeckel JA, Daniel S, Treggiari M. Randomized Pilot Trial of Two Modified Endotracheal Tubes To Prevent Ventilator-associated Pneumonia. Annals Of The American Thoracic Society 2016, 13: 72-80. PMID: 26523433, PMCID: PMC4722846, DOI: 10.1513/annalsats.201506-346oc.Peer-Reviewed Original ResearchConceptsEndotracheal tubeTracheal colonizationChest radiograph criteriaOccurrence of VAPPrevention of VAPCoprimary end pointsSerious adverse eventsInstitutional review board approvalEmergency endotracheal intubationStandard endotracheal tubeMajority of intubationsReview board approvalModified Endotracheal TubeSafety concernsAdverse eventsVAP preventionEndotracheal intubationSubglottic secretionsEmergency intubationClinical trialsClinical signsNosocomial infectionsPilot trialStudy groupHospital setting
2005
Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department
Merlani PG, Pasquina P, Granier JM, Treggiari M, Rutschmann O, Ricou B. Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department. Academic Emergency Medicine 2005, 12: 1206-1215. PMID: 16293895, DOI: 10.1197/j.aem.2005.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedEmergency Service, HospitalFemaleHospitalizationHumansIntubation, IntratrachealMaleMultivariate AnalysisOutcome and Process Assessment, Health CarePositive-Pressure RespirationPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsSensitivity and SpecificitySurvival AnalysisSwitzerlandTreatment FailureConceptsNoninvasive positive pressure ventilationFailure of NPPVAcute respiratory failurePositive pressure ventilationEmergency departmentRespiratory rateRespiratory failurePressure ventilationEndotracheal intubationNPPV failureGlasgow Coma Scale scoreSubsequent endotracheal intubationNegative predictive valueED admissionInstitutional protocolFactors AssociatedPatientsPredictive valueScale scoreMultivariate analysisIntubationVentilationFailureHoursDepartment