2014
Long-Term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia*
Khandelwal N, Hough CL, Bansal A, Veenstra DL, Treggiari MM. Long-Term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia*. Critical Care Medicine 2014, 42: 1610-1618. PMID: 24732240, PMCID: PMC4061153, DOI: 10.1097/ccm.0000000000000322.Peer-Reviewed Original ResearchConceptsSevere acute respiratory distress syndromeAcute respiratory distress syndromeRespiratory distress syndromeLong-term survivalRescue therapyProportional hazards modelHospital mortalityDistress syndromeICU admissionHazard ratioHospital dischargeSevere acute respiratory distress syndrome (ARDS) patientsAcute respiratory distress syndrome survivorsConventional treatmentAcute respiratory distress syndrome patientsPaO2/FiO2 ratioBetter long-term survivalRespiratory distress syndrome patientsLevel 1 trauma centerMeeting study inclusion criteriaCox proportional hazards modelHigher hospital mortalityKaplan-Meier methodState death registryStudy inclusion criteria
2011
Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury
Chaiwat O, Vavilala MS, Philip S, Malakouti A, Neff MJ, Deem S, Treggiari MM, Wang J, Lang JD. Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. Journal Of Critical Care 2011, 26: 144-151. PMID: 20869200, DOI: 10.1016/j.jcrc.2010.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAcute Lung InjuryAdolescentAdultAgedAged, 80 and overAPACHECritical IllnessFemaleGuideline AdherenceHospital MortalityHumansInjury Severity ScoreIntraoperative PeriodLength of StayMaleMiddle AgedPositive-Pressure RespirationPractice Guidelines as TopicRetrospective StudiesRisk FactorsTidal VolumeYoung AdultConceptsAcute respiratory distress syndromeAcute lung injuryALI/acute respiratory distress syndromeLTV ventilationLung injuryClinical outcomesLow tidal volume ventilation strategyALI/ARDS diagnosisLow tidal volume ventilationVolume ventilation strategyRespiratory distress syndromeTidal volume ventilationARDS diagnosisHospital mortalityIntraoperative adherenceHospital lengthSecondary outcomesSurgical patientsDistress syndromeIll patientsVolume ventilationImproved oxygenationPatient outcomesRetrospective analysisMAIN OUTCOME
2009
Atrial and brain natriuretic peptide concentrations and the response to inhaled nitric oxide in patients with acute respiratory distress syndrome
Treggiari MM, Bendjelid K, Yanez ND, Heidegger CP, Suter PM, Romand JA. Atrial and brain natriuretic peptide concentrations and the response to inhaled nitric oxide in patients with acute respiratory distress syndrome. Journal Of Critical Care 2009, 25: 23-29. PMID: 19327320, DOI: 10.1016/j.jcrc.2008.10.014.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeAtrial natriuretic peptideBaseline atrial natriuretic peptideRespiratory distress syndromeNT-proNatriuretic peptideBNP concentrationsDistress syndromeCardiac peptidesHigh atrial natriuretic peptideBrain natriuretic peptide concentrationsB-type natriuretic peptideNitric oxideCyclic guanosine monophosphate concentrationBaseline NT-proProspective cohort studyNatriuretic peptide concentrationsSubgroup of patientsCardiac natriuretic peptidesGuanosine monophosphate concentrationCyclic guanosine monophosphateIntrapulmonary shuntCohort studyConsecutive patientsClinical benefit
2004
Effect of acute lung injury and acute respiratory distress syndrome on outcome in critically ill trauma patients*
Treggiari MM, Hudson LD, Martin DP, Weiss NS, Caldwell E, Rubenfeld G. Effect of acute lung injury and acute respiratory distress syndrome on outcome in critically ill trauma patients*. Critical Care Medicine 2004, 32: 327-331. PMID: 14758144, DOI: 10.1097/01.ccm.0000108870.09693.42.Peer-Reviewed Original ResearchConceptsALI/acute respiratory distress syndromeAcute respiratory distress syndromeAcute lung injuryAcute Physiology ScoreRespiratory distress syndromeTrauma patientsHospital mortalityPhysiology ScoreLung injuryDistress syndromeSeverity scoreHospital costsTrauma severityAmerican-European Consensus Conference definitionPresence of ALIIntensive care unit admissionIntensive care unit stayIll trauma patientsCare unit admissionInjury Severity ScoreConsensus Conference definitionLevel I centersCrude relative riskIntensive care unitLength of stay
2002
Air cysts and bronchiectasis prevail in nondependent areas in severe acute respiratory distress syndrome: A computed tomographic study of ventilator-associated changes
Treggiari MM, Romand JA, Martin JB, Suter PM. Air cysts and bronchiectasis prevail in nondependent areas in severe acute respiratory distress syndrome: A computed tomographic study of ventilator-associated changes. Critical Care Medicine 2002, 30: 1747-1752. PMID: 12163787, DOI: 10.1097/00003246-200208000-00012.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAPACHEBronchiectasisBronchogenic CystFemaleHumansLungLung ComplianceLung InjuryMaleMiddle AgedPneumothoraxPredictive Value of TestsPrevalenceRespiratory Distress SyndromeRetrospective StudiesSeverity of Illness IndexStatistics as TopicSurvival AnalysisSwitzerlandTime FactorsTomography, X-Ray ComputedTreatment FailureVentilators, MechanicalConceptsSevere acute respiratory distress syndromeAcute respiratory distress syndromeRespiratory distress syndromeMechanical ventilationAir cystsDistress syndromeHigh end-inspiratory pressuresVentilator-induced lung damageRetrospective observational studyPresence of pneumothoraxEnd-inspiratory pressureHigh inspiratory pressuresSeverity of changesNondependent areasLung damageInspiratory pressureMinute ventilationTomographic scanOdds ratioTomographic scanningObservational studyLung fieldsTidal volumeBronchial divisionsAbnormal parenchyma