2023
Intraprocedural C‐arm dual‐phase cone‐beam enhancement patterns correlate with tumor absorbed dose after radioembolization
Bastiaannet R, Lin M, Frey E, de Jong H. Intraprocedural C‐arm dual‐phase cone‐beam enhancement patterns correlate with tumor absorbed dose after radioembolization. Medical Physics 2023, 51: 3045-3052. PMID: 38064591, PMCID: PMC10994751, DOI: 10.1002/mp.16882.Peer-Reviewed Original ResearchContrast-enhanced cone-beam CTHepatocellular carcinomaPET/CT scansNon-tumor liver tissuesPersonalized treatment planningIntra-procedural imagingBlood flow patternsPretreatment tumorRetrospective studyLimits of agreementTumor responseBland-Altman analysisClinical trialsTumor doseCT scanEnhancement patternHepatic vasculatureHCC tumorsCatheter positionTumor tissueLiver tissueTumorsHepatic radioembolizationPatientsDose
2022
NIMG-07. APPLYING A GLIOMA-TRAINED DEEP LEARNING AUTO-SEGMENTATION TOOL ON BM PRE- AND POST-RADIOSURGERY
Kaur M, Varghese S, Jekel L, Tillmanns N, Merkaj S, Bousabarah K, Lin M, Bhawnani J, Chiang V, Aboian M. NIMG-07. APPLYING A GLIOMA-TRAINED DEEP LEARNING AUTO-SEGMENTATION TOOL ON BM PRE- AND POST-RADIOSURGERY. Neuro-Oncology 2022, 24: vii162-vii163. PMCID: PMC9660643, DOI: 10.1093/neuonc/noac209.626.Peer-Reviewed Original ResearchStereotactic radiosurgeryPosttreatment lesionsBoard-certified neuroradiologistsRoutine clinical useWhole tumorTumor coreMulticentric lesionsTreatment responsePeritumoral edemaBM preLesionsClinical useVolumetric segmentationEdemaPatientsT2w FLAIRTherapy planningTumorsDedicated trainingLesion detectionBM dataVolumetric measurementsBMMRIPre
2021
Lipiodol Deposition and Washout in Primary and Metastatic Liver Tumors After Chemoembolization
Nezami N, VAN Breugel JMM, Konstantinidis M, Chapiro J, Savic LJ, Miszczuk MA, Rexha I, Lin M, Hong K, Georgiades C. Lipiodol Deposition and Washout in Primary and Metastatic Liver Tumors After Chemoembolization. In Vivo 2021, 35: 3261-3270. PMID: 34697157, PMCID: PMC8627740, DOI: 10.21873/invivo.12621.Peer-Reviewed Original ResearchConceptsConventional trans-arterial chemoembolizationTrans-arterial chemoembolizationNeuroendocrine tumorsColorectal carcinomaIntrahepatic cholangiocarcinomaLipiodol depositionWashout rateContrast-enhanced magnetic resonanceMetastatic liver tumorsColorectal carcinoma tumorsLiver metastasesHepatic metastasesTumor responseTarget lesionsRetrospective analysisLiver tumorsSmall tumorsChemoembolizationCarcinoma tumorsTumorsExponential washoutCarcinomaTomography imagingWashoutCholangiocarcinoma
2020
Automated feature quantification of Lipiodol as imaging biomarker to predict therapeutic efficacy of conventional transarterial chemoembolization of liver cancer
Stark S, Wang C, Savic LJ, Letzen B, Schobert I, Miszczuk M, Murali N, Oestmann P, Gebauer B, Lin M, Duncan J, Schlachter T, Chapiro J. Automated feature quantification of Lipiodol as imaging biomarker to predict therapeutic efficacy of conventional transarterial chemoembolization of liver cancer. Scientific Reports 2020, 10: 18026. PMID: 33093524, PMCID: PMC7582153, DOI: 10.1038/s41598-020-75120-7.Peer-Reviewed Original ResearchConceptsConventional transarterial chemoembolizationLipiodol depositionTransarterial chemoembolizationLiver cancerPeripheral depositionLipiodol depositsTherapeutic efficacyNecrotic tumor areasBaseline MRITherapy optionsTumor responseTreatment responseTumor volumeLiver lesionsLipiodolH postTumor areaH-CTHounsfield unitsBiomarkersChemoembolizationHigh rateTumorsCancerImproved response
2018
4:21 PM Abstract No. 331 Quantitative analysis of Lipiodol washout rates in intrahepatic cholangiocarcinoma and hepatic metastasis from neuroendocrine tumors and colorectal cancer after chemoembolization
Nezami N, Van Breugel M, Miszczuk M, Rexha I, Windham-Herman A, Savic L, Murali N, Lin M, Chapiro J, Geschwin J. 4:21 PM Abstract No. 331 Quantitative analysis of Lipiodol washout rates in intrahepatic cholangiocarcinoma and hepatic metastasis from neuroendocrine tumors and colorectal cancer after chemoembolization. Journal Of Vascular And Interventional Radiology 2018, 29: s142. DOI: 10.1016/j.jvir.2018.01.367.Peer-Reviewed Original Research
2016
3:36 PMAbstract No. 73 Randomized controlled trial of cone beam CT (CBCT) with navigation software versus standard CBCT and angiography guidance for chemoembolization of liver tumors
Abi-Jaoudeh N, Duran R, Lin M, Tacher V, Funai E, Schernthaner R, Skopec M, Dunklin T, Smolka S, Sahu S, Carelsen B, van der Bom M, Radaelli A, Geschwind J, Wood B. 3:36 PMAbstract No. 73 Randomized controlled trial of cone beam CT (CBCT) with navigation software versus standard CBCT and angiography guidance for chemoembolization of liver tumors. Journal Of Vascular And Interventional Radiology 2016, 27: s37. DOI: 10.1016/j.jvir.2015.12.106.Peer-Reviewed Original Research
2015
Feasibility of a Modified Cone-Beam CT Rotation Trajectory to Improve Liver Periphery Visualization during Transarterial Chemoembolization.
Schernthaner RE, Chapiro J, Sahu S, Withagen P, Duran R, Sohn JH, Radaelli A, van der Bom IM, Geschwind JF, Lin M. Feasibility of a Modified Cone-Beam CT Rotation Trajectory to Improve Liver Periphery Visualization during Transarterial Chemoembolization. Radiology 2015, 277: 833-41. PMID: 26000642, PMCID: PMC4654716, DOI: 10.1148/radiol.2015142821.Peer-Reviewed Original ResearchConceptsCone-beam CTTransarterial chemoembolizationLiver volumeRadiation exposureInstitutional review board-approved studyPeripheral hepatic tumorsSecondary liver cancerCT radiation exposureCone beam CT examinationsBoard-approved studyTumor detectabilityRadiation exposure reductionHepatic tumorsCT examinationsLiver cancerCT protocolPatientsCone beamMagnetic resonance imagesCT indicesC-arm rotatesCTTumorsExposure reductionRank testHow I Do It: Cone-Beam CT during Transarterial Chemoembolization for Liver Cancer
Tacher V, Radaelli A, Lin M, Geschwind JF. How I Do It: Cone-Beam CT during Transarterial Chemoembolization for Liver Cancer. Radiology 2015, 274: 320-334. PMID: 25625741, PMCID: PMC4314294, DOI: 10.1148/radiol.14131925.Peer-Reviewed Original ResearchConceptsTransarterial chemoembolizationLiver cancerContrast material injection protocolsTime of procedureTwo-dimensional angiographyClinical evidenceTreatment successLiver tumorsMicrocatheter placementInterventional radiologyInterventional proceduresCBCT technologyDiagnostic imagingCone beamInjection protocolCBCT techniqueCBCT imagingCone-beam CTTumorsRoutine utilizationChemoembolizationCBCT imagesC-armCancerCBCT5:00 PM, Abstract No. 168 Evaluation of novel inherently radio-opaque beads for embolotherapy of liver tumors
Duran R, Sharma K, Mirpour S, Ashrafi K, Lewis A, Reyes J, Tacher V, Willis S, Dreher M, Lin M, Geschwind J. 5:00 PM, Abstract No. 168 Evaluation of novel inherently radio-opaque beads for embolotherapy of liver tumors. Journal Of Vascular And Interventional Radiology 2015, 26: s79. DOI: 10.1016/j.jvir.2014.12.220.Peer-Reviewed Original Research
2014
Assessing tumor response after loco-regional liver cancer therapies: the role of 3D MRI
Chapiro J, Lin M, Duran R, Schernthaner RE, Geschwind JF. Assessing tumor response after loco-regional liver cancer therapies: the role of 3D MRI. Expert Review Of Anticancer Therapy 2014, 15: 199-205. PMID: 25371052, PMCID: PMC4304995, DOI: 10.1586/14737140.2015.978861.Peer-Reviewed Original ResearchConceptsTumor responseResponse Evaluation CriteriaTumor response criteriaMajor clinical interestLiver cancer therapyLiver cancer lesionsClinical evidenceIntraarterial therapyCancer lesionsSolid tumorsResponse criteriaAnatomic methodsClinical interestImaging modalitiesCancer therapyTumor analysisTherapyMRILesionsTumors
2013
Quantitative Assessment of Lipiodol Deposition after Chemoembolization: Comparison between Cone-Beam CT and Multidetector CT
Chen R, Geschwind J, Wang Z, Tacher V, Lin M. Quantitative Assessment of Lipiodol Deposition after Chemoembolization: Comparison between Cone-Beam CT and Multidetector CT. Journal Of Vascular And Interventional Radiology 2013, 24: 1837-1844. PMID: 24094672, PMCID: PMC3840104, DOI: 10.1016/j.jvir.2013.08.017.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularChemoembolization, TherapeuticCone-Beam Computed TomographyContrast MediaEthiodized OilFemaleHumansImaging, Three-DimensionalLinear ModelsLiver NeoplasmsMaleMiddle AgedMultidetector Computed TomographyPredictive Value of TestsRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesTumor BurdenWorkflowConceptsTransarterial chemoembolizationLipiodol depositionHepatocellular carcinomaMultidetector CTConventional transarterial chemoembolizationVolume of tumorMargin of tumorUnenhanced multidetector CTUnenhanced multidetectorLipiodol retentionChemoembolizationLiver parenchymaTumorsEntire tumorLiver contrastCone beamCone-beam CTCTImaging modalitiesCBCTPatientsLipiodolWhole tumorVolumetric measurementsTomographyCan C-Arm Cone-Beam CT Detect a Micro-Embolic Effect After TheraSphere Radioembolization of Neuroendocrine and Carcinoid Liver Metastasis?
Pellerin O, Lin M, Bhagat N, Shao W, Geschwind J. Can C-Arm Cone-Beam CT Detect a Micro-Embolic Effect After TheraSphere Radioembolization of Neuroendocrine and Carcinoid Liver Metastasis? Cancer Biotherapy & Radiopharmaceuticals 2013, 28: 459-465. PMID: 23484809, PMCID: PMC3715773, DOI: 10.1089/cbr.2012.1390.Peer-Reviewed Original ResearchConceptsTumor enhancementHounsfield unitsArterial phaseCapillary levelCarcinoid liver metastasesYttrium-90 microspheresHigh-dose radiationEarly arterial phaseContrast medium injectionC-arm cone-beam CTTheraSphere radioembolizationLiver metastasesNeuroendocrine tumorsHepatic tumorsDelayed phasesRadioembolizationTumor densityMedium injectionTumor attenuationTumor vesselsTumorsTheraSphereEmbolic effectCone-beam CTSignificant decrease
2011
Comparing the Detectability of Hepatocellular Carcinoma by C-Arm Dual-Phase Cone-Beam Computed Tomography During Hepatic Arteriography With Conventional Contrast-Enhanced Magnetic Resonance Imaging
Loffroy R, Lin M, Rao P, Bhagat N, Noordhoek N, Radaelli A, Blijd J, Geschwind J. Comparing the Detectability of Hepatocellular Carcinoma by C-Arm Dual-Phase Cone-Beam Computed Tomography During Hepatic Arteriography With Conventional Contrast-Enhanced Magnetic Resonance Imaging. CardioVascular And Interventional Radiology 2011, 35: 97-104. PMID: 21328023, DOI: 10.1007/s00270-011-0118-x.Peer-Reviewed Original ResearchConceptsHCC lesionsMagnetic resonance imagingHepatocellular carcinomaHepatic arteriographyVenous phaseArterial phaseDrug-Eluting Beads Transarterial ChemoembolizationCE-MRIResonance imagingContrast-enhanced magnetic resonance imagingGold standardResultsSeventy-sevenTransarterial chemoembolizationHCC nodulesTerms of conspicuitySufficient image qualityTumorsDiagnostic imagingLesionsArteriographyCE-MR imagesCarcinomaLiverTomographyImaging