2024
Enhancing clinical decision-making: An externally validated machine learning model for predicting isocitrate dehydrogenase mutation in gliomas using radiomics from presurgical magnetic resonance imaging
Lost J, Ashraf N, Jekel L, von Reppert M, Tillmanns N, Willms K, Merkaj S, Petersen G, Avesta A, Ramakrishnan D, Omuro A, Nabavizadeh A, Bakas S, Bousabarah K, Lin M, Aneja S, Sabel M, Aboian M. Enhancing clinical decision-making: An externally validated machine learning model for predicting isocitrate dehydrogenase mutation in gliomas using radiomics from presurgical magnetic resonance imaging. Neuro-Oncology Advances 2024, 6: vdae157. PMID: 39659829, PMCID: PMC11630777, DOI: 10.1093/noajnl/vdae157.Peer-Reviewed Original ResearchIsocitrate dehydrogenase mutation statusArea under the curveMagnetic resonance imagingMutation statusML modelsMachine learningSemi-automated tumour segmentationsPre-surgical magnetic resonance imagingCare of glioma patientsMachine learning modelsClinical care of glioma patientsIsocitrate dehydrogenase statusAnnotated datasetsFeature extractionPrediction taskMulti-institutional dataModel trainingIDH mutationsPredicting IDH mutationLearning modelsRetrospective studyHeterogeneous datasetsTumor segmentationGlioma patientsBrain tumors
2022
Machine Learning Models for Classifying High- and Low-Grade Gliomas: A Systematic Review and Quality of Reporting Analysis
Bahar RC, Merkaj S, Petersen G, Tillmanns N, Subramanian H, Brim WR, Zeevi T, Staib L, Kazarian E, Lin M, Bousabarah K, Huttner AJ, Pala A, Payabvash S, Ivanidze J, Cui J, Malhotra A, Aboian MS. Machine Learning Models for Classifying High- and Low-Grade Gliomas: A Systematic Review and Quality of Reporting Analysis. Frontiers In Oncology 2022, 12: 856231. PMID: 35530302, PMCID: PMC9076130, DOI: 10.3389/fonc.2022.856231.Peer-Reviewed Original ResearchMachine learning modelsLearning modelConvolutional neural networkDeep learning studiesLarge training datasetsGrade predictionSupport vector machineApplication of MLNeural networkConventional machineVector machineTraining datasetBest performing modelCommon algorithmsModel performanceEssential metricMean prediction accuracyHigh predictive accuracyPrediction accuracyPerforming modelMachinePrediction modelDiagnosis statementsAccuracy statementsLearning studies