2024
Enhancing clinical decision-making: An externally validated machine learning model for predicting isocitrate dehydrogenase mutation in gliomas using radiomics from presurgical magnetic resonance imaging
Lost J, Ashraf N, Jekel L, von Reppert M, Tillmanns N, Willms K, Merkaj S, Petersen G, Avesta A, Ramakrishnan D, Omuro A, Nabavizadeh A, Bakas S, Bousabarah K, Lin M, Aneja S, Sabel M, Aboian M. Enhancing clinical decision-making: An externally validated machine learning model for predicting isocitrate dehydrogenase mutation in gliomas using radiomics from presurgical magnetic resonance imaging. Neuro-Oncology Advances 2024, 6: vdae157. PMID: 39659829, PMCID: PMC11630777, DOI: 10.1093/noajnl/vdae157.Peer-Reviewed Original ResearchIsocitrate dehydrogenase mutation statusArea under the curveMagnetic resonance imagingMutation statusML modelsMachine learningSemi-automated tumour segmentationsPre-surgical magnetic resonance imagingCare of glioma patientsMachine learning modelsClinical care of glioma patientsIsocitrate dehydrogenase statusAnnotated datasetsFeature extractionPrediction taskMulti-institutional dataModel trainingIDH mutationsPredicting IDH mutationLearning modelsRetrospective studyHeterogeneous datasetsTumor segmentationGlioma patientsBrain tumors
2022
Machine Learning Tools for Image-Based Glioma Grading and the Quality of Their Reporting: Challenges and Opportunities
Merkaj S, Bahar RC, Zeevi T, Lin M, Ikuta I, Bousabarah K, Petersen G, Staib L, Payabvash S, Mongan JT, Cha S, Aboian MS. Machine Learning Tools for Image-Based Glioma Grading and the Quality of Their Reporting: Challenges and Opportunities. Cancers 2022, 14: 2623. PMID: 35681603, PMCID: PMC9179416, DOI: 10.3390/cancers14112623.Peer-Reviewed Original ResearchMachine learning toolsGrade predictionLearning toolsML applicationsClassifier algorithmML modelsClassification methodMedical imagingData sourcesPractices of radiologistsToolGlioma gradingNext stepWorkflowAlgorithmChallengesTechnological innovationImplementationPredictionModelLast decadeSpecific areas