2024
Patlak-Guided Self-Supervised Learning for Dynamic PET Denoising
Liu Q, Guo X, Tsai Y, Gallezot J, Chen M, Guo L, Xie H, Pucar D, Young C, Panin V, Carson R, Liu C. Patlak-Guided Self-Supervised Learning for Dynamic PET Denoising. 2024, 00: 1-2. DOI: 10.1109/nss/mic/rtsd57108.2024.10655866.Peer-Reviewed Original ResearchPre-trained modelsSelf-supervised learning methodSuperior noise reductionNoise reductionDynamic framesImage quality improvementUpsampling blockSignal-to-noise ratioWeight initializationWeak supervisionDynamic PET datasetsEnhanced noise reductionUNet modelLearning methodsTraining schemeTemporal dataStatic imagesDenoisingReconstruction methodPET datasetsLesion signal-to-noise ratioSize constraintsLesion SNRImagesReconPopulation-based deep image prior for dynamic PET denoising: A data-driven approach to improve parametric quantification
Liu Q, Tsai Y, Gallezot J, Guo X, Chen M, Pucar D, Young C, Panin V, Casey M, Miao T, Xie H, Chen X, Zhou B, Carson R, Liu C. Population-based deep image prior for dynamic PET denoising: A data-driven approach to improve parametric quantification. Medical Image Analysis 2024, 95: 103180. PMID: 38657423, DOI: 10.1016/j.media.2024.103180.Peer-Reviewed Original ResearchDeep Image PriorImage priorsSupervised modelsNoise reductionIntrinsic image featuresDeep learning techniquesU-Net architectureNovel denoising techniqueQuality of parametric imagesDenoising modelDenoising techniquesStatic datasetsBaseline techniquesEffective noise reductionData-driven approachLearning techniquesDynamic datasetsOptimization processPrior informationStatic imagesHigh noise levelsImage featuresDatasetPrior imagePET datasets
2022
Virtual high‐count PET image generation using a deep learning method
Liu J, Ren S, Wang R, Mirian N, Tsai Y, Kulon M, Pucar D, Chen M, Liu C. Virtual high‐count PET image generation using a deep learning method. Medical Physics 2022, 49: 5830-5840. PMID: 35880541, PMCID: PMC9474624, DOI: 10.1002/mp.15867.Peer-Reviewed Original ResearchConceptsStructural similarity indexImage quality evaluationDeep learning-based methodsDeep learning methodsImage qualityLearning-based methodsPET datasetsStatic datasetsDL methodsNet networkImage generationPET imagesNetwork inputsImage counterpartsLearning methodsNetwork outputTraining datasetPeak signalPositron emission tomography (PET) imagesQuality evaluationDatasetCross-validation resultsMean square errorHigh-count imagesImages