The Increased Expression of Gelatinolytic Proteases Due to Gigarette Smoking Exposure in the Lung of Guinea Pig
Kang M, Lee J, Yoo C, Lee G, Chung H, Seo J, Kim Y, Han S, Shim Y. The Increased Expression of Gelatinolytic Proteases Due to Gigarette Smoking Exposure in the Lung of Guinea Pig. Tuberculosis And Respiratory Diseases 2001, 50: 426-436. DOI: 10.4046/trd.2001.50.4.426.Peer-Reviewed Original ResearchPathogenesis of COPDInflammatory cellular infiltrationIntraalveolar cellsCS exposureGuinea pigsCellular infiltrationLung parenchymeHistologic changesAlveolar wallsGelatinolytic enzymesAlveolar inflammatory cellsBAL fluid cellsDuration of CSDays/weekHours/daySmoking exposureBAL fluidInflammatory cellsLung parenchymaWeek groupMMP expressionGelatin zymographyControl groupAdult populationDestructive changes